Results 31 to 40 of about 1,872,403 (242)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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Hybrid Adaptive Sliding Mode Controller for Path Tracking of Wheeled Mobile Robot in Uncertainty
Ain Shams Engineering JournalIn this paper robust kinematic based adaptive sliding mode controller (KASMC) and dynamic based adaptive sliding mode controller (DASMC) are proposed for path tracking of wheeled-mobile-robot (WMR).
Madhu Sudan Das +2 more
doaj +1 more source
Safety research on stabilization of autonomous vehicles based on improved-LQR control
AIP Advances, 2022 Mediating the divergent interest of vehicle stability and strengthened path tracking performance when aiming at the design of a path tracking controller for autonomous vehicles is a challenging issue.
Hao Li +4 more
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
An integrated path-tracking and control allocation method for autonomous racing electric vehicles [PDF]
In recent years, path-tracking controllers for autonomous passenger vehicles and Control Allocation (CA) methods for handling and stability control have both received extensive discussion in the literature.
Li, B. +4 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Steering control based on model predictive control for obstacle avoidance of unmanned ground vehicle
Measurement + Control, 2020 In this paper, a strategy based on model predictive control consisting of path planning and path tracking is designed for obstacle avoidance steering control problem of the unmanned ground vehicle.
Chaofang Hu +4 more
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Minimum time control for path tracking problem of intelligent vehicle handling in inverse dynamics
Advances in Mechanical EngineeringThe continuous development of vehicle intelligence and electronic technology has greatly promoted the vigorous development of the automotive industry.
Shanshan Guo, Yingjie Liu
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