Results 61 to 70 of about 391,643 (293)
SECOND INTERNATIONAL SYMPOSIUM ON RANAVIRUSES:: A NORTH AMERICAN HERPETOLOGICAL PERSPECTIVE [PDF]
, 2014 Ranaviruses are large double stranded DNA viruses of poikilothermic vertebrates including amphibians, reptiles and fish. In North America, ranaviral disease and ranavirus-related die-off events have been documented in all three classes.
Brunner, Jesse L. +3 more
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Usefulness of plasminogen activator inhibitor-1 as a predictive marker of mortality in sepsis
Journal of Intensive Care, 2017 Background Sepsis is one of the most significant causes of mortality in intensive care units. It indicates crosstalk between inflammation and coagulation.
Kota Hoshino +6 more
doaj +1 more source
NLRP3: Role in ischemia/reperfusion injuries
Frontiers in Immunology, 2022 NLR family pyrin domain containing 3 (NLRP3) is expressed in immune cells, especially in dendritic cells and macrophages and acts as a constituent of the inflammasome.
Soudeh Ghafouri-Fard +10 more
doaj +1 more source
'Towards a Conceptual Framework for Innate Immunity' [PDF]
, 2005 Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Twycross, Jamie
core +3 more sources
Treponemal Phospholipids Inhibit Innate Immune Responses Induced by Pathogen-associated Molecular Patterns [PDF]
Journal of Biological Chemistry, 2003 Host innate immune responses to microbial components, known as pathogen-associated molecular patterns (PAMPs), are regulated and modified by cellular receptors and serum proteins, including Toll-like receptors (TLRs), CD14, and LPS-binding protein (LBP). We demonstrated that a treponemal membrane lipid inhibited PAMPs-induced immune responses.
Masahito, Hashimoto +2 more
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Molecular Plant-Microbe Interactions, 2006 Nonspecific recognition of pathogen-derived general elicitors triggers the first line of plant basal defense, which in turn, preconditions the host towards resistance or susceptibility. To elucidate how basal defense responses influence the onset of Mla (
Rico A. Caldo +3 more
doaj +1 more source
Animals, 2022 The presence of β-mannans in feed can produce a futile and chronic immune stimulation in fattening pigs. In this trial, a 1-4-endo-D-β-mannanase was added to the feed (HC) during growth and fattening (0.03% of Hemicell HT) and physical performance and ...
Pedro Sánchez-Uribe +9 more
doaj +1 more source
Various forms of tissue damage and danger signals following hematopoietic stem-cell transplantation [PDF]
, 2015 Hematopoietic stem-cell transplantation (HSCT) is the most potent curative therapy for many malignant and non-malignant disorders. Unfortunately, a major complication of HSCT is graft-versus-host disease (GVHD), which is mediated by tissue damage ...
Paczesny, Sophie, Ramadan, Abdularouf
core +2 more sources