Results 11 to 20 of about 633,152 (295)
Pattern recognition receptor signaling and innate immune responses to schistosome infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Schistosomiasis remains to be a significant public health problem in tropical and subtropical regions. Despite remarkable progress that has been made in the control of the disease over the past decades, its elimination remains a daunting challenge in ...
Nouhoum Dibo +6 more
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Pattern recognition receptor agonists in pathogen vaccines mediate antitumor T-cell cross-priming [PDF]
Journal for ImmunoTherapy of Cancer, 2023 Background Cancer immunotherapies are generally effective in patients whose tumors contain a priori primed T-cells reactive to tumor antigens (TA).
Michael Yellin +13 more
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Activation of the pattern recognition receptor NOD1 augments colon cancer metastasis
Protein & Cell, 2020 While emerging data suggest nucleotide oligomerization domain receptor 1 (NOD1), a cytoplasmic pattern recognition receptor, may play an important and complementary role in the immune response to bacterial infection, its role in cancer metastasis is ...
Henry Y. Jiang +18 more
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The Emerging Roles of Pellino Family in Pattern Recognition Receptor Signaling [PDF]
Frontiers in Immunology, 2022 The Pellino family is a novel and well-conserved E3 ubiquitin ligase family and consists of Pellino1, Pellino2, and Pellino3. Each family member exhibits a highly conserved structure providing ubiquitin ligase activity without abrogating cell and ...
E Zhang, Xia Li, Xia Li
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Dynamin-Related Proteins Enhance Tomato Immunity by Mediating Pattern Recognition Receptor Trafficking [PDF]
Membranes, 2022 Pattern recognition receptor (PRR) trafficking to the plasma membrane and endocytosis plays a crucial role in pattern triggered immunity (PTI). Dynamin-related proteins (DRPs) participate in endocytosis and recycling.
Meirav Leibman-Markus +5 more
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Inflammasome-Associated Gastric Tumorigenesis Is Independent of the NLRP3 Pattern Recognition Receptor [PDF]
Frontiers in Oncology, 2022 Inflammasomes are important multiprotein regulatory complexes of innate immunity and have recently emerged as playing divergent roles in numerous inflammation-associated cancers.
Alice J. West +12 more
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Frontiers in Immunology, 2017 DM9 domain was first identified in Drosophila melanogaster, and it was subsequently found to integrate with or without other protein domains across a wide range of invertebrates and vertebrates.
Shuai Jiang +13 more
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Cnidarian Pattern Recognition Receptor Repertoires Reflect Both Phylogeny and Life History Traits [PDF]
Frontiers in Immunology, 2021 Pattern recognition receptors (PRRs) are evolutionarily ancient and crucial components of innate immunity, recognizing danger-associated molecular patterns (DAMPs) and activating host defenses.
Madison A. Emery +2 more
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Inhibitory pattern recognition receptors
Journal of Experimental Medicine, 2021 Pathogen- and damage-associated molecular patterns are sensed by the immune system’s pattern recognition receptors (PRRs) upon contact with a microbe or damaged tissue. In situations such as contact with commensals or during physiological cell death, the immune system should not respond to these patterns.
Matevž Rumpret +3 more
openaire +3 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Toll/Toll-like receptors are key regulators of the innate immune system in both invertebrates and vertebrates. However, while mammalian Toll-like receptors function as pattern recognition receptors that directly bind microbe-associated ...
Ruonan Zhang +13 more
semanticscholar +1 more source