Results 61 to 70 of about 861,453 (229)
Redistribution of critical major histocompatibility complex and T cell receptor-binding functions of residues in an antigenic sequence after biterminal substitution [PDF]
, 1991 Residues critical for establishing a trimolecular interaction with a major histocompatibility complex (MHC)-encoded receptor and a T cell antigen receptor (TcR) were determined for an antigenic nonapeptide. The N-terminal residue proved to be involved in
Allen +18 more
core +1 more source
Pattern recognition receptors in antifungal immunity [PDF]
Seminars in Immunopathology, 2014 Receptors of the innate immune system are the first line of defence against infection, being able to recognise and initiate an inflammatory response to invading microorganisms. The Toll-like (TLR), NOD-like (NLR), RIG-I-like (RLR) and C-type lectin-like receptors (CLR) are four receptor families that contribute to the recognition of a vast range of ...
Plato, Anthony +2 more
openaire +3 more sources
EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans
Nature Microbiology, 2017 Oral epithelial cells discriminate between pathogenic and non-pathogenic stimuli, and only induce an inflammatory response when they are exposed to high levels of a potentially harmful microorganism. The pattern recognition receptors (PRRs) in epithelial
M. Swidergall +3 more
semanticscholar +1 more source
Recognition of Pep-13/25 MAMPs of Phytophthora localizes to an RLK locus in Solanum microdontum
Frontiers in Plant Science, 2023 Pattern-triggered immunity (PTI) in plants is mediated by cell surface-localized pattern recognition receptors (PRRs) upon perception of microbe-associated molecular pattern (MAMPs). MAMPs are conserved molecules across microbe species, or even kingdoms,
Xiao Lin +12 more
doaj +1 more source
Nature Communications, 2018 Detection of conserved microbial patterns by host cell surface pattern recognition receptors (PRRs) activates innate immunity. The FLAGELLIN-SENSITIVE 2 (FLS2) receptor perceives bacterial flagellin and recruits another PRR, BAK1 and the cytoplasmic ...
Beatriz Orosa +11 more
semanticscholar +1 more source
Reciprocal Inhibition of Adiponectin and Innate Lung Immune Responses to Chitin and Aspergillus fumigatus [PDF]
, 2019 Chitin is a structural biopolymer found in numerous organisms, including pathogenic fungi, and recognized as an immune-stimulating pathogen associated molecular pattern by pattern recognition molecules of the host immune system.
Amarsaikhan, Nansalmaa +6 more
core +4 more sources
Molecular Plant-Microbe Interactions, 2023 Plants rely on innate immune systems to defend against a wide variety of biotic attackers. Key components of innate immunity include cell-surface pattern-recognition receptors (PRRs), which recognize pest- and pathogen-associated molecular patterns ...
Anthony G. K. Garcia +1 more
doaj +1 more source
Expression of CD226 is associated to but not required for NK cell education [PDF]
, 2017 DNAX accessory molecule-1 (DNAM-1, also known as CD226) is an activating receptor expressed on subsets of natural killer (NK) and T cells, interacts with its ligands CD155 or CD112, and has co-varied expression with inhibitory receptors. Since inhibitory
Bernhardt, Günter +9 more
core +2 more sources
Frontiers in Immunology, 2017 Age-related decline in immunity is characterized by stem cell exhaustion, telomere shortening, and disruption of cell-to-cell communication, leading to increased patient risk of disease.
S. Jose +4 more
semanticscholar +1 more source
Primary immunodeficiencies of pattern recognition receptors [PDF]
Journal of Internal Medicine, 2012 AbstractPrimary immunodeficiencies (PIDs) are severe defects in the capacity of the host to mount a proper immune response, and are characterized by an increased susceptibility to infections. Although classical immunodeficiencies have been characterized based on broad defects in cell populations (e.g.
Netea, M.G. +2 more
openaire +3 more sources