Results 11 to 20 of about 188,478 (231)
Pattern recognition receptors and autophagy [PDF]
Frontiers in Immunology, 2014 The immune system senses exogenous threats or endogenous stress through specialized machinery known as pattern recognition receptors (PRRs). These receptors recognize conserved molecular structures and initiate downstream signaling pathways to control ...
Ji Eun eOh, Heung Kyu eLee
doaj +4 more sources
Pattern recognition receptors and gastric cancer [PDF]
Frontiers in Immunology, 2014 Chronic inflammation has been associated with an increased risk of several human malignancies, a classic example being gastric cancer (GC). Development of GC is known to result from infection of the gastric mucosa by Helicobacter pylori, which initially ...
Natalia eCastaño-Rodriguez +2 more
doaj +4 more sources
Pattern recognition receptors in HIV transmission [PDF]
Frontiers in Immunology, 2012 Dendritic cells (DCs), Langerhans cells (LCs) and macrophages are innate immune cells that reside in genital and intestinal mucosal tissues susceptible to HIV-1 infection.
Teunis B. Geijtenbeek, Annelies eMesman
doaj +4 more sources
Editorial: Pattern-recognition receptors: Genetics, immunity, pathology [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Petro Starokadomskyy
doaj +2 more sources
Inhibitory pattern recognition receptors. [PDF]
J Exp Med, 2022 Pathogen- and damage-associated molecular patterns are sensed by the immune system’s pattern recognition receptors (PRRs) upon contact with a microbe or damaged tissue. In situations such as contact with commensals or during physiological cell death, the immune system should not respond to these patterns.
Rumpret M +3 more
europepmc +4 more sources
Japanese Journal of Clinical Immunology, 2011 Immunity is based on self/nonself discrimination. In vertebrates, two major systems, innate and adaptive immune systems, constitute host defense against invading microbes. Adaptive immunity is characterized by specific immune responses through B- or T-cell antigen receptors that are generated by somatic recombination, whereas nonspecific responses to ...
Takaya, Hayashi +2 more
openaire +4 more sources
Anti-Viral Pattern Recognition Receptors as Therapeutic Targets
Cells, 2021 Pattern recognition receptors (PRRs) play a central role in the inflammation that ensues following microbial infection by their recognition of molecular patterns present in invading microorganisms but also following tissue damage by recognising molecules
Conor Hennessy, Declan P. McKernan
doaj +1 more source
European Journal of Inflammation, 2021 Human breast milk (HBM) contains many bioactive components that protect infants from various microorganisms. Pattern recognition receptors on phagocytic cells recognize microbial pathogens and promote the innate immune system.
Won-Ho Hahn +3 more
doaj +1 more source
Intracellular PRRs Activation in Targeting the Immune Response Against Fungal Infections
Frontiers in Cellular and Infection Microbiology, 2020 The immune response against fungal infections is complex and exhibits several factors involving innate elements that participate in the interaction with the fungus. The innate immune system developed pattern recognition receptors that recognize different
Grasielle Pereira Jannuzzi +4 more
doaj +1 more source
Current Research in Structural Biology, 2023 Reducing inflammation by diet is a major goal for prevention or lowering symptoms of a variety of diseases, such as auto-immune reactions and cancers.
Lucas de Freitas Pedrosa +2 more
doaj +1 more source