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Patulin is produced by species of Penicillium, Aspergillus and Byssochlamys. It is a mycotoxin that primarily contaminates pome fruit products, but is being reported from other fruit and foods, for example shellfish and cheese. New findings reveal that patulin binds to the bases of DNA, in addition to its well-established ability to conjugate ...
Wright, Sandra A. I.,
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Patulin: Mechanism of genotoxicity
Food and Chemical Toxicology, 2012Patulin is a frequently found food contaminant mainly produced by the fungi Aspergillus and Penicillium. Patulin is suspected to be clastogenic, mutagenic, teratogenic and in higher concentrations cytotoxic. Here, we investigate the mechanism of the patulin-induced genotoxicity.
Helga Stopper
exaly +3 more sources
Patulin is a toxic mycotoxin usually associated with apple products. Due to its unhealthy effects for humans, its content is regulated by the food safety authorities.
Inmaculada Viñas +2 more
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Biosynthesis and Toxicological Effects of Patulin
Patulin is a toxic chemical contaminant produced by several species of mold, especially within Aspergillus, Penicillium and Byssochlamys. It is the most common mycotoxin found in apples and apple-derived products such as juice, cider, compotes and other ...
Isabelle P Oswald +2 more
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S-Adenosylmethionine-Dependent Methyltransferase Helps Pichia caribbica Degrade Patulin
Patulin contamination not only is a menace to human health but also causes serious environmental problems worldwide due to the synthetic fungicides that are used to control it.
Hongyin Zhang +2 more
exaly +3 more sources
Experientia, 1949
Die Erwagungen, welche die Autoren zu der Struktur I fur Patulin fuhrten, werden kurz beschrieben, und es wird gezeigt, das das chemische Verhalten des Naturstoffes in jeder Hinsicht durch diese Strukturformel zu erklaren ist.
R B, WOODWARD, G, SINGH
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Die Erwagungen, welche die Autoren zu der Struktur I fur Patulin fuhrten, werden kurz beschrieben, und es wird gezeigt, das das chemische Verhalten des Naturstoffes in jeder Hinsicht durch diese Strukturformel zu erklaren ist.
R B, WOODWARD, G, SINGH
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Production of patulin by Micromycetes
Mycopathologia, 1989In the context of the screening for antifungal and antibacterial molecules among the Micromycetes, we investigated the ability of 850 strains grown in liquid medium to produce patulin. The compound was produced by 58 fungi, most of which had not been mentioned in the literature, especially Mucorales and Fungi Imperfecti.
R, Steiman +3 more
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The spasmolytic effect of patulin
Experientia, 1958Patulin verhindert die Kontraktion des isolierten Meerschweinchenileums, verursacht durch Nikotin, Histamin, 5-Hydroxytryptamin, Pilokarpin, Acetylcholin und Prostaglandin. Die Kontraktion, verursacht durch Substanz P und Barium Chloride, wird nicht verhindert.
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Bioorganic Chemistry, 1973
Abstract The biosynthesis of the antibiotic patulin (II) from 6-methylsalicyclic acid (6-MSA) (I) in replacement cultures of Penicillium patulum has been examined with 2H and 14 C 3 H -labeled intermediates. Efficient utilization of m-cresol (IX), m-hydroxybenzyl alcohol (V), m-hydroxybenzaldehyde (XII), gentisaldehyde (VIII), and ...
A.I. Scott +3 more
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Abstract The biosynthesis of the antibiotic patulin (II) from 6-methylsalicyclic acid (6-MSA) (I) in replacement cultures of Penicillium patulum has been examined with 2H and 14 C 3 H -labeled intermediates. Efficient utilization of m-cresol (IX), m-hydroxybenzyl alcohol (V), m-hydroxybenzaldehyde (XII), gentisaldehyde (VIII), and ...
A.I. Scott +3 more
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Patulin in apple leather in Iran
Food Additives & Contaminants: Part B, 2013Apple leather is made by dehydration of cooked fruit into leathery sheets. Mould growth and patulin production can occur in damaged apples or when fallen fruit is collected for apple leather processing. A survey was conducted to determine levels and dietary intake of patulin from apple leather marketed in Iran.
H, Montaseri +7 more
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