Results 121 to 130 of about 19,447 (222)

Biallelic PAX7 variants cause a novel Satellite Cell-opathy with progressive muscle involvement resembling facioscapulohumeral muscular dystrophy

open access: yesCell Death and Disease
Inherited myopathies are genetic disorders characterised by declining motor function due to progressive muscle weakening and wasting. Recently, pathogenic variants in PAX7, the master transcriptional regulator of muscle stem cells, have been associated ...
Massimo Ganassi   +18 more
doaj   +1 more source

The Effect of Geranylgeraniol and Ginger on Satellite Cells Myogenic State in Type 2 Diabetic Rats

open access: yesCurrent Issues in Molecular Biology
Type 2 diabetes (T2D) is associated with increased inflammation and reactive oxygen species (ROS) in muscles, leading to basal satellite cell (SC) myogenic impairment (i.e., reduction in SC pool), which is critical for maintaining skeletal muscle mass ...
Nigel C. Jiwan   +4 more
doaj   +1 more source

Isolation of Myogenic Nuclei from Whole Muscle Tissue [PDF]

open access: yes, 2015
Isolation of myogenic cell populations from whole skeletal muscle is necessary to elucidate the molecular repair mechanisms involved in skeletal muscle maintenance and regeneration that can be damaged when affected by diseases or aging, often severely ...
Brewer, Owen
core   +2 more sources

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