Results 111 to 120 of about 19,447 (222)

Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors

open access: yesStem Cell Reports, 2018
Summary: Skeletal muscle harbors quiescent stem cells termed satellite cells and proliferative progenitors termed myoblasts, which play pivotal roles during muscle regeneration.
Ori Bar-Nur   +18 more
doaj   +1 more source

Association studies and direct DNA sequencing implicate some known genetic susceptibility loci in the etiology of nonsyndromic orofacial clefts in sub-Saharan African populations [PDF]

open access: yes, 2016
Orofacial clefts (OFCs) are congenital dysmorphologies of the human face and oral cavity, with a global incidence of 1 per 700 live births. These anomalies exhibit multifactorial pattern of inheritance, with both genetic and environmental factors playing
A. Butali   +37 more
core   +2 more sources

Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures

open access: yesSkeletal Muscle, 2017
Background Facioscapulohumeral muscular dystrophy (FSHD) is most commonly inherited in an autosomal dominant pattern and caused by the abnormal expression of DUX4 in skeletal muscle.
Premi Haynes   +3 more
doaj   +1 more source

The origin of embryonic and fetal myoblasts: a role of Pax3 and Pax7.

open access: yesGenes & development, 2009
Skeletal muscle is a heterogeneous tissue composed of individual muscle fibers, diversified in size, shape, and contractile protein content, to fulfill the different functional needs of the vertebrate body. This heterogeneity derives from and depends at least in part on distinct classes of myogenic progenitors; i.e., embryonic and fetal myoblasts and ...
G. Messina, G. Cossu
openaire   +2 more sources

Bovine satellite cell Pax7 ICC v1 [PDF]

open access: yes, 2019
Staining primary bovine satellite cells for Pax7, a common marker of satellite cells and myogenic potential. Protocol developed for https://www.thermofisher.com/antibody/product/PAX7-Antibody-Polyclonal/PA5-68506 (Thermo Fisher Pax7 antibody PA5-68506; rabbit IgG anti-Pax7)
Andrew Stout, Natalie Rubio
openaire   +2 more sources

Core promoter short tandem repeats as evolutionary switch codes for primate speciation [PDF]

open access: yes, 2015
Alteration in gene expression levels underlies many of the phenotypic differences across species. Because of their highly mutable nature, proximity to the +1 transcription start site (TSS), and the emerging evidence of functional impact on gene ...
Bagheri, A.   +8 more
core  

Bone growth following demineralized bone matrix implantation requires angiogenesis [PDF]

open access: yes, 2016
Angiogenesis is required for endochondral ossification during development and fracture healing; however the exact mechanisms and temporal relationship between the two processes remains unclear.
Lam, Stephanie
core  

Abstract 028 | Modelling satellite cell dysfunction to understand pathogenesis of neuromuscular disorders

open access: yesEuropean Journal of Translational Myology
Muscle maintenance and regeneration depend on satellite cells, the resident stem cells of skeletal muscle. Impaired satellite cell function is increasingly recognized as a key contributor to many neuromuscular disorders.
Massimo Ganassi
doaj   +1 more source

Skeletal muscle as an experimental model of choice to study tissue aging and rejuvenation. [PDF]

open access: yes, 2020
Skeletal muscle is among the most age-sensitive tissues in mammal organisms. Significant changes in its resident stem cells (i.e., satellite cells, SCs), differentiated cells (i.e., myofibers), and extracellular matrix cause a decline in tissue ...
Conboy, Irina M   +4 more
core  

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