Results 91 to 100 of about 19,447 (222)

Gene regulatory networks that control the specification of neural-crest cells in the lamprey [PDF]

, 2009
The lamprey is the only basal vertebrate in which large-scale gene perturbation analyses are feasible at present. Studies on this unique animal model promise to contribute both to the understanding of the basic neural-crest gene regulatory network ...
Bronner-Fraser, Marianne, Nikitina, Natalya V.   +1 more
core   +1 more source

Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening

Nature Communications, 2019
Pioneer transcription factor Pax7 specifies melanotrope cells, which then allows for the binding of Tpit transcription factor. Here, authors find that while binding of heterochromatin targeting by Pax7 is independent of Tpit, Pax7-dependent chromatin ...
Alexandre Mayran, Kevin Sochodolsky, Konstantin Khetchoumian, Juliette Harris, Yves Gauthier, Amandine Bemmo, Aurelio Balsalobre, Jacques Drouin   +7 more
doaj   +1 more source

Prenatal muscle development in a mouse model for the secondary dystroglycanopathies [PDF]

, 2016
The defective glycosylation of α-dystroglycan is associated with a group of muscular dystrophies that are collectively referred to as the secondary dystroglycanopathies.
A Leschziner, A Matsakas, A Yoshida, AM Beedle, AR Raphael, B Xia, B-V BD de, C Godfrey, C Longman, C Whitmore, CA Schneider, D Merrick, D Montarras, DE Michele, DJ Blake, DJ Lefeber, E Hohenester, E Stevens, F Muntoni, H Yin, J Reeuwijk van, J Ross, JB Miller, K Buysse, K Kobayashi, KM Wright, KP Campbell, L Wells, M Brockington, M Brockington, M Kanagawa, M Kanagawa, M Narusawa, M Ontell, MD Henry, MJ Duxson, MM Goddeeris, MR Ackroyd, MR Ackroyd, O Armand, S Chan, S Cirak, S Costanzo Di, S Sato, S Schiaffino, S Sugita, SC Brown, T Roscioli, T Willer, TJ Hawke   +49 more
core   +2 more sources

Clinicopathological Characteristics and Outcomes of Genitourinary Rhabdomyosarcoma in Two Girls

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Rhabdomyosarcoma (RMS) is a soft tissue neoplasm accounting for about 8% of solid tumors in children. There are mainly four histologic subtypes of RMS: embryonal, alveolar, spindle cell/sclerosing, and pleomorphic. The genitourinary tract is the second most affected primary site of RMS. Genitourinary RMS is more common in young boys than girls.
George Evele, Francine Kouya, George Ngock, Richard Bardin   +3 more
wiley   +1 more source

Next‐Generation Sustainable Food Production Through Integrative Biotechnology, AI, and Climate‐Resilient Innovations

Food and Energy Security, Volume 15, Issue 3, May/June 2026.
ABSTRACT By 2050, the global population is projected to reach ~10 billion, leading to 50% increase in food demand. This growth will place immense pressure on agricultural systems that are already struggling with the impacts of climate change and resource depletion.
Chaquayla Katam, Hajra Maqsood, Brooke Bucci, Sixue Chen   +3 more
wiley   +1 more source

Notch Signaling Rescues Loss of Satellite Cells Lacking Pax7 and Promotes Brown Adipogenic Differentiation

Cell Reports, 2016
Pax7 is a nodal transcription factor that is essential for regulating the maintenance, expansion, and myogenic identity of satellite cells during both neonatal and adult myogenesis.
Alessandra Pasut, Natasha C. Chang, Uxia Gurriaran Rodriguez, Sharlene Faulkes, Hang Yin, Melanie Lacaria, Hong Ming, Michael A. Rudnicki   +7 more
doaj   +1 more source

Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy. [PDF]

, 2019
Many potentially therapeutic molecules have been identified for treating Duchenne muscular dystrophy. However, targeting those molecules only to sites of active pathology is an obstacle to their clinical use.
Bertoni, Carmen, Flores, Ivan, Ramos, Julian, Tidball, James G, Wang, Ying, Wehling-Henricks, Michelle, Welc, Steven S   +6 more
core  

What determines growth potential and juvenile quality of farmed fish species? [PDF]

, 2013
Enhanced production of high quality and healthy fry is a key target for a successful and competitive expansion of the aquaculture industry. Although large quantities of fish larvae are produced, survival rates are often low or highly variable and growth ...
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core   +3 more sources

Exercise and Skeletal Muscle‐Derived Extracellular Vesicles: Their Cargo, Release, and Role in Metabolic Regulation

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT The health benefits of exercise are well established in the prevention and management of metabolic disorders such as obesity and diabetes. Emerging evidence indicates that extracellular vesicles (EVs) may contribute to the beneficial effects of exercise.
Jeremy Boulestreau, Scott K. Ferguson, Luke Nelson, Noemi Polgar   +3 more
wiley   +1 more source

Pax7 is required for establishment of the xanthophore lineage in zebrafish embryos

Molecular Biology of the Cell, 2016
The pigment pattern of many animal species is a result of the arrangement of different types of pigment-producing chromatophores. The zebrafish has three different types of chromatophores: black melanophores, yellow xanthophores, and shimmering iridophores arranged in a characteristic pattern of golden and blue horizontal stripes.
Nord, Hanna, Dennhag, Nils, Muck, Joscha, von Hofsten, Jonas   +3 more
openaire   +3 more sources