Results 101 to 110 of about 19,447 (222)
Liver International, Volume 46, Issue 5, May 2026.ABSTRACT Background Liver‐related sarcopenia is a devastating systemic complication of chronic liver disease (CLD) driven by mechanisms extending beyond nutritional deficiency. However, the role of liver‐derived humoral factors remains unclear. We utilised a unique cohort of human skeletal muscle biopsies to test the hypothesis that serum conjugated ...
Motoh Iwasa +16 more
wiley +1 more source
Macrophage-released ADAMTS1 promotes muscle stem cell activation. [PDF]
, 2017 Coordinated activation of muscle stem cells (known as satellite cells) is critical for postnatal muscle growth and regeneration. The muscle stem cell niche is central for regulating the activation state of satellite cells, but the specific extracellular ...
Aggarwal, Abhishek +7 more
core +2 more sources
Physiological Reports, Volume 14, Issue 9, May 2026.Abstract Skeletal muscles are exquisitely designed to produce force that facilitate movement. Circadian “molecular clocks” residing in muscle play a role in regulating force production with muscle stem cell (satellite cells, SC) molecular clocks modulating isometric and eccentric force according to time‐of‐day.
Ryan E. Kahn +2 more
wiley +1 more source
MLL1 is required for PAX7 expression and satellite cell self-renewal in mice
Nature Communications, 2019 PAX7 transcription factor specifies the myogenic identity of muscle stem cells and acts as a nodal factor by stimulating proliferation while inhibiting differentiation.
Gregory C. Addicks +7 more
doaj +1 more source
In situ macrophage phenotypic transition is affected by altered cellular composition prior to acute sterile muscle injury [PDF]
, 2017 K
Contreras, Gerardo Alvarado +9 more
core +2 more sources
Regulation of Pax7 protein levels by caspase-3 and proteasome activity in differentiating myoblasts
Biological Research, 2011 The transcription factor Pax7 negatively regulates the activity of the muscle regulatory transcription factor MyoD, preventing muscle precursor cells from undergoing terminal differentiation.
Hugo C Olguín
doaj
PLoS ONEEssential for muscle fiber formation and hypertrophy, muscle stem cells, also called satellite cells, reside beneath the basal lamina of the muscle fiber.
Cécile Rallière +3 more
doaj +1 more source
The Satellite Cell Niche Regulates the Balance between Myoblast Differentiation and Self-Renewal via p53 [PDF]
, 2018 Satellite cells are adult muscle stem cells residing in a specialized niche that regulates their homeostasis. How niche-generated signals integrate to regulate gene expression in satellite cell-derived myoblasts is poorly understood.
Antczak, Philipp +5 more
core +2 more sources
Segregation of striated and smooth muscle lineages by a Notch-dependent regulatory network [PDF]
, 2014 Background: Lineage segregation from multipotent epithelia is a central theme in development and in adult stem cell plasticity. Previously, we demonstrated that striated and smooth muscle cells share a common progenitor within their epithelium of origin,
Applebaum, Mordechai +2 more
core +2 more sources
Comparative expression analysis of Pax3 and Pax7 during mouse myogenesis
The International Journal of Developmental Biology, 2006 Pax3 and Pax7 are closely related transcription factors involved in the commitment of myogenic precursors in the developing trunk. However, it is not yet clear whether these genes are required for myogenic cell specification in the head and for post-somitic myogensis per se.
David, Horst +6 more
openaire +3 more sources