Results 61 to 70 of about 773 (143)

Regulatory and Industry Perspective on the Model Master File Framework for Locally Acting Drug Products. [PDF]

Pharm Res
Walenga RL, Alam K, Clarke JF, De Backer J, Fridén M, Hamadeh A, Mowli J, Sonti S, Spires J, Tan ML, Musuamba FT, Tsakalozou E.   +11 more
europepmc   +3 more sources

'Part'ly first among equals: Semantic part-based benchmarking for state-of-the-art object recognition systems

, 2016
An examination of object recognition challenge leaderboards (ILSVRC, PASCAL-VOC) reveals that the top-performing classifiers typically exhibit small differences amongst themselves in terms of error rate/mAP.
A Borji, A Khosla, A Torralba, CW Tyler, D Hoiem, GA Miller, L Xu, M Everingham, MD Zeiler, PF Felzenszwalb, SE Palmer, T Tommasi, T-Y Lin   +12 more
core   +1 more source

Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia [PDF]

, 2017
Drug sensitivity and resistance testing on diagnostic leukemia samples should provide important functional information to guide actionable target and biomarker discovery.
Balasubramanian, Gnana P., Bandapalli, Obul R., Bornhauser, Beat C., Bourquin, Jean-Pierre, Brown, Timothy J., Cario, Gunnar, Chang, Bill H., Collins, Robert H., Delorenzi, Mauro, Diaz-Flores, Ernesto, Dobay, Maria Pamela, Dunn, Samuel H., Eckert, Cornelia, Eugster, Sabrina, Frismantas, Viktoras, Higi, Salome, Horvath, Peter, Irving, Julie A., Jenni, Silvia, Kulozik, Andreas E., Kunz, Joachim, Loh, Mignon L., Marovca, Blerim, Meisel, Roland, Muckenthaler, Martina U., Pail, Orrin, Radimerski, Thomas, Richter-Pechanska, Paulina, Rinaldi, Anna, Saha, Vaskar, Schrappe, Martin, Stanulla, Martin, Tchinda, Joelle, Tyner, Jeffrey W., Uhrig, Sebastian, Voegeli, Pamela, Von Stackelberg, Arend   +36 more
core   +1 more source

Integration of advanced methods and models to study drug absorption and related processes : An UNGAP perspective [PDF]

, 2021
Funding Information: AI acknowledges the support of projects icp009 (ALKOOL) of PRACE-ICEI (grant agreement 800858) for awarding access to Piz Daint, at the Swiss National Supercomputing Centre (CSCS), Switzerland and BG05M2OP001–1.001–0004 (UNITe) of ...
Aarons, Leon, Augustijns, Patrick, Brouwers, Joachim, Darwich, Adam S., De Waal, Tom, Garbacz, Grzegorz, García-Horsman, J. Arturo, Hansmann, Simone, Hoc, Dagmara, Ivanova, Anela, Koziolek, Mirko, Reppas, Christos, Schick, Philipp, Vertzoni, Maria, Wilson, Clive G.   +14 more
core   +3 more sources

Bottomonium dipion transitions

, 2008
Dipion transitions of the subthreshold bottomonium levels $\Upsilon (nS)\to \Upsilon (n'S) \pi\pi$ with $n>n', n=2,3,4, n'=1,2$ are studied in the framework of the chiral decay Lagrangian, derived earlier.
A. I. Veselov, M. B. Voloshin, M. B. Voloshin, M. B. Voloshin, M. B. Voloshin, Yu. A. Simonov, Yu. A. Simonov   +6 more
core   +1 more source

A Combined Modeling Approach to Predict the Effect of Gastric Emptying Delay on the Pharmacokinetics of Small Molecules

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 12, Page 2026-2039, December 2025.
ABSTRACT Dulaglutide, a long‐acting glucagon‐like peptide‐1 (GLP‐1) receptor agonist, is approved for improving glycemic control and reducing cardiovascular risks in patients with type 2 diabetes mellitus (T2DM). This research investigates the effect of dulaglutide on gastric emptying and its impact on the pharmacokinetics (PK) of orally administered ...
Maria M. Posada, Karen B. Schneck, Bridget L. Morse, Luc R. A. Rougee, Lai San Tham, Jessica F. Rehmel, Brian Thompson, Stephen D. Stamatis, Stephen D. Hall, Gemma L. Dickinson   +9 more
wiley   +1 more source

An Open‐Source Framework for Virtual Bioequivalence Modeling and Clinical Trial Design

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 12, Page 1932-1948, December 2025.
ABSTRACT To establish bioequivalence (BE) of a generic test formulation with respect to a reference listed drug, it is necessary to demonstrate a comparable rate and extent to which active ingredients reach the site of action. To decrease unnecessary human testing and simulate scenarios involving specific populations or challenges with recruitment or ...
Abdullah Hamadeh, Moriah Pellowe, Pierre Chelle, Cindy Hoi Ting Yeung, Julian Otalvaro, Walter Yamada, Jay Bartroff, Alona Kryshchenko, André Dallmann, Juri Solodenko, Jörg Lippert, Eleftheria Tsakalozou, Michael Neely, Andrea Edginton   +13 more
wiley   +1 more source

Pemanfaatan Sastra Anak Sebagai Media Mitigasi Bencana [PDF]

, 2010
This article is about a study explaining: (1) kinds of the children literature that could be use as the media for disaster\u27s mitigation; (2) Compatibility and the accuracy of the child\u27s literature for its prospective reader based on the cognitive ...
Liliani, E. (Else)
core  

Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola^® on the Luminal and Systemic Behavior of Loratadine (BCS Class 2b)

Pharmaceutics, 2020
In the present work, we explored if Coca-Cola® had a beneficial impact on the systemic outcome of the weakly basic drug loratadine (Wal-itin®, immediate-release formulation, 10 mg, generic drug product).
Bart Hens, Marival Bermejo, Patrick Augustijns, Rodrigo Cristofoletti, Gregory E. Amidon, Gordon L. Amidon   +5 more
doaj   +1 more source

Carteiras eficientes e técnicas para o seu cálculo [PDF]

, 2013
Titulación: Administración de Dirección de Empresas -- Materia: Investimentos FinanceirosEsta unidade didáctica enmárcase na materia de Investimentos Financeiros correspondente ao 4º curso do Grao en Administración e Dirección de Empresas, é unha ...
López Penabad, María Celia
core