Results 71 to 80 of about 773 (143)
Integrisani biofarmaceutski pristup u razvoju i karakterizaciji lekova: opšti koncept i primena [PDF]
, 2020 The importance of biopharmaceutical considerations in pharmaceutical development and drug characterization has been well recognized both by pharmaceutical industry and regulatory authorities as a tool to establish predictive relationships between drug ...
Cvijić, Sandra +2 more
core +1 more source
The Journal of Clinical Pharmacology, Volume 64, Issue 9, Page 1055-1067, September 2024.Abstract Since the Open Source Initiative laid the foundation for the open source software environment in 1998, the popularity of free and open source software has been steadily increasing. Model‐informed drug discovery and development (MID3), a key component of pharmaceutical research and development, heavily makes use of computational models which ...
André Dallmann +4 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 13, Issue 8, Page 1366-1379, August 2024.Abstract A physiologically‐based pharmacokinetic (PBPK) model for tipifarnib, which included mechanistic absorption, was built and verified by integrating in vitro data and several clinical data in healthy subjects and cancer patients. The final PBPK model was able to recover the clinically observed single and multiple‐dose plasma concentrations of ...
Noriko Okudaira +2 more
wiley +1 more source
Global imbalances from the historical perspective [PDF]
, 2011 "This paper examines the global imbalances in two eras of globalization. The main focus is on the medium-run factors that determine the current account balances.
Veselkova, Marcela
core +2 more sources
Local Wisdom and Natural Disaster in West Sumatra [PDF]
, 2017 Community-based disaster management is an attempt to optimize the potential of social and local values in communities to facilitate the handling of natural disasters.
Rozi, S. (Syafwan)
core
Cultural transmission and discrimination [PDF]
, 2005 Each worker belongs to either the majority or the minority group and, irrespective of the group she belongs to, can have good or bad work habits. These traits are transmitted from one generation to the next through a learning and imitation process which ...
Sáez-Martí, María, Zenou, Yves
core
Oral absorption from surfactant-based drug formulations:the impact of molecularly dissolved drug on bioavailability [PDF]
Enabling drug formulations are often required to ensure sufficient absorption after oral administration of poorly soluble drugs. While these formulations typically increase the apparent solubility of the drug, it is widely acknowledged that only ...
Bauer-Brandl, Annette +5 more
core +1 more source
East Asia and Global Imbalances: Saving, Investment, and Financial Development [PDF]
We investigate the role of budget balances, financial development and openness, in the evolution of global imbalances. Financial development -- or the lack thereof -- has received considerable attention as a possible contributing factor to the ...
Hiro Ito, Menzie Chinn
core
Conservation Easements and the Proceeds Regulation [PDF]
, 2021 This article provides an in-depth look at Treasury Regulation § 1.170A-14(g)(6)(ii), known as the proceeds regulation. The proceeds regulation is intended to protect the public investment in conservation if a perpetual conservation easement that was the ...
McLaughlin, Nancy
core +1 more source
The Global Bioequivalence Harmonisation Initiative (GBHI): Report of the sixth international EUFEPS/PQRI conference [PDF]
At the 6th International Conference of the Global Bioequivalence Harmonisation Initiative (GBHI), co-organised by the European Federation of Pharmaceutical Sciences (EUFEPS) and the Product Quality Research Institute (PQRI), critical bioequivalence (BE ...
Beuerle, G. +9 more
core +1 more source