Results 41 to 50 of about 527,000 (340)
Collisional energy dependence of peptide ion fragmentation [PDF]
Journal of the American Society for Mass Spectrometry, 2009 The energy dependence of fragmentation in a collision cell was measured for 2400 protonated peptide ions derived from the digestion of 24 proteins. The collision voltage at which the sum of the fragment ion abundances was equal to the remaining parent ion (V(1/2)) was the principal measure of fragmentation effectiveness.
Neta, Pedatsur +3 more
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MethodsX, 2021 The semenogelin 1 protein is secreted in the seminal vesicles. After ejaculation it is split into small peptide fragments using internal proteases.
Aydar Bikmullin +3 more
doaj +1 more source
Fragment synthesis of disulfide-containing peptides
MethodsX, 2020 A new strategy for solid phase peptide synthesis in the fragment synthesis based on the use of 2-Cl-trityl resin as carrier to obtain protected peptide-resin and Rink Amide Resin, HOBT/HBTU or PyBOP/DIPEA or HATU/DIPEA as the coupling method is described. The highlights of this method are:•Simple.•Low cost.•Solid phase based.
Yuxuan Dai +3 more
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Modeling peptide fragmentation with dynamic Bayesian networks for peptide identification [PDF]
Bioinformatics, 2008 AbstractMotivation: Tandem mass spectrometry (MS/MS) is an indispensable technology for identification of proteins from complex mixtures. Proteins are digested to peptides that are then identified by their fragmentation patterns in the mass spectrometer.
Klammer, Aaron A. +4 more
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Nature Communications, 2022 Peptide fragments derived from the interfaces of protein-protein interactions (PPIs) provide useful templates for designing small molecule PPI inhibitors.
Xiyao Cheng +8 more
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Accurate Peptide Fragment Mass Analysis: Multiplexed Peptide Identification and Quantification [PDF]
Journal of Proteome Research, 2012 Fourier transform-all reaction monitoring (FT-ARM) is a novel approach for the identification and quantification of peptides that relies upon the selectivity of high mass accuracy data and the specificity of peptide fragmentation patterns. An FT-ARM experiment involves continuous, data-independent, high mass accuracy MS/MS acquisition spanning a ...
Chad R, Weisbrod +4 more
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Probing the mechanism of electron capture and electron transfer dissociation using tags with variable electron affinity [PDF]
, 2009 Electron capture dissociation (ECD) and electron transfer dissociation (ETD) of doubly protonated electron affinity (EA)-tuned peptides were studied to further illuminate the mechanism of these processes. The model peptide FQpSEEQQQTEDELQDK, containing a
Beauchamp, J. L. +5 more
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Atypical signaling and functional desensitization response of MAS receptor to peptide ligands. [PDF]
PLoS ONE, 2014 MAS is a G protein-coupled receptor (GPCR) implicated in multiple physiological processes. Several physiological peptide ligands such as angiotensin-(1-7), angiotensin fragments and neuropeptide FF (NPFF) are reported to act on MAS.
Kalyan C Tirupula +3 more
doaj +1 more source
Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]
, 2014 BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P +5 more
core +1 more source
Unusual fragmentation of derivatized cysteine‐containing peptides [PDF]
Rapid Communications in Mass Spectrometry, 2018 Rationale Modification of cysteines by aminoethylation results in side chains similar to those of lysine. Trypsin cleaves at this modified residue and this labeling method can facilitate the analysis of proteins, specifically antibodies.
Nick Degraan‐Weber +2 more
openaire +2 more sources