Results 41 to 50 of about 2,203,634 (375)
Effect of phenylalanine on the fragmentation of deprotonated peptides [PDF]
Journal of the American Society for Mass Spectrometry, 2002 The fragmentation reactions of a variety of deprotonated dipeptides and tripeptides containing phenylalanine have been studied using energy-resolved collision-induced dissociation, isotopic labeling and MS/MS/MS experiments. The benzyl a-group has a substantial effect on the fragmentation reactions observed.
openaire +3 more sources
Epitope mapping using mRNA display and a unidirectional nested deletion library [PDF]
, 2005 In vitro selection targeting an anti-polyhistidine monoclonal antibody was performed using mRNA display with a random, unconstrained 27-mer peptide library.
Ja, William W. +2 more
core +1 more source
Antigenic Determinant of Trichosanthin Peptide Fragments
Immunopharmacology and Immunotoxicology, 1986 Purified plant protein, Trichosanthin (TCS), was partially digested with chymotrypsin to produce peptide fragments. Two large fragments, I and II, have been isolated and identified as C-terminal peptides located at sequence positions between 79-234 and 107-234. Their molecular weights determined by electrophoretic mobility on SDS gel were 16,000 and 14,
Zhen Yao +3 more
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Collisional energy dependence of peptide ion fragmentation [PDF]
Journal of the American Society for Mass Spectrometry, 2009 The energy dependence of fragmentation in a collision cell was measured for 2400 protonated peptide ions derived from the digestion of 24 proteins. The collision voltage at which the sum of the fragment ion abundances was equal to the remaining parent ion (V(1/2)) was the principal measure of fragmentation effectiveness.
Stephen E. Stein +3 more
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High-resolution global peptide-protein docking using fragments-based PIPER-FlexPepDock
bioRxiv, 2017 Peptide-protein interactions contribute a significant fraction of the protein-protein interactome. Accurate modeling of these interactions is challenging due to the vast conformational space associated with interactions of highly flexible peptides with ...
Nawsad Alam +5 more
semanticscholar +1 more source
Improved Detection and Fragmentation of Disulphide-Linked Peptides [PDF]
Methods and Protocols, 2018 Characterisation of peptides containing intact disulphide bonds (DSBs) via mass spectrometry is challenging. Our study demonstrates that the addition of aniline to alpha-cyano-4-hydroxycinnamic acid improves detection and fragmentation of complex DSB peptides by matrix-assisted laser desorption/ionization, tandem time-of-flight mass spectrometry (MALDI-
Santanu Deb-Choudhury +3 more
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A peptide filtering relation quantifies MHC class I peptide optimization.
PLoS Computational Biology, 2011 Major Histocompatibility Complex (MHC) class I molecules enable cytotoxic T lymphocytes to destroy virus-infected or cancerous cells, thereby preventing disease progression. MHC class I molecules provide a snapshot of the contents of a cell by binding to
Neil Dalchau +7 more
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Atypical signaling and functional desensitization response of MAS receptor to peptide ligands. [PDF]
PLoS ONE, 2014 MAS is a G protein-coupled receptor (GPCR) implicated in multiple physiological processes. Several physiological peptide ligands such as angiotensin-(1-7), angiotensin fragments and neuropeptide FF (NPFF) are reported to act on MAS.
Kalyan C Tirupula +3 more
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Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups [PDF]
, 2017 Current diagnostic tests applied to inflammatory arthritis lack the necessary specificity to appropriately categorise patients. There is a need for novel approaches to classify patients with these conditions.
Gaya, Daniel +9 more
core +2 more sources
Brazilian Journal of Medical and Biological Research, 1999 Studies concerning the antigenicity of thyroglobulin fragments allow the characterization of the epitopes but do not consider the role of heavier antigenic fragments that could result in vivo from the action of endoproteases.
L.H.B. Boechat, R.L. Zollner
doaj +1 more source