Results 31 to 40 of about 433,652 (251)

Hydrogen-rich saline injection into the subarachnoid cavity within 2 weeks promotes recovery after acute spinal cord injury

open access: yesNeural Regeneration Research, 2015
Hydrogen can relieve tissue-damaging oxidative stress, inflammation and apoptosis. Injection of hydrogen-rich saline is an effective method for transporting molecular hydrogen.
Jian-long Wang   +6 more
doaj   +1 more source

Molecular Screening Strategy to Identify a Non-invasive Delivery Mechanism for the Treatment of Middle Ear Disorders

open access: yesFrontiers in Medicine, 2020
Middle ear ailments include a broad range of pathological conditions. Otitis media is the leading middle ear disease of childhood, which incurs significant health care resources in developed countries and, in developing countries, causes significant ...
Arwa Kurabi   +7 more
doaj   +1 more source

Immunogenicity of NS4b dengue 3 virus mimotope presented to the immune system as multiple antigen peptide system [PDF]

open access: yes, 2013
The availability of random peptide libraries displayed on bacteriophage (RPL) has provided a powerful tool for selecting sequences that mimic binding properties of natural antigen epitopes (mimotopes). These mimotopes can be used for vaccine design, drug
Acosta, Armando   +11 more
core   +2 more sources

Nerve autografts and tissue-engineered materials for the repair of peripheral nerve injuries: a 5-year bibliometric analysis

open access: yesNeural Regeneration Research, 2015
With advances in biomedical methods, tissue-engineered materials have developed rapidly as an alternative to nerve autografts for the repair of peripheral nerve injuries. However, the materials selected for use in the repair of peripheral nerve injuries,
Yuan Gao   +6 more
doaj   +1 more source

Rapid Optimization of Mcl-1 Inhibitors using Stapled Peptide Libraries Including Non-Natural Side Chains [PDF]

open access: yes, 2018
Alpha helices form a critical part of the binding interface for many protein-protein interactions, and chemically stabilized synthetic helical peptides can be effective inhibitors of such helix-mediated complexes.
Keating, Amy E.   +3 more
core   +1 more source

Hydrogen sulfide intervention in focal cerebral ischemia/reperfusion injury in rats

open access: yesNeural Regeneration Research, 2015
The present study aimed to explore the mechanism underlying the protective effects of hydrogen sulfide against neuronal damage caused by cerebral ischemia/reperfusion.
Xin-juan Li   +6 more
doaj   +1 more source

Erythromycin Resistance Peptides Selected from Random Peptide Libraries [PDF]

open access: yesJournal of Biological Chemistry, 1997
Translation of a 5-codon mini-gene encoded in Escherichia coli 23 S rRNA was previously shown to render cells resistant to erythromycin (Tenson, T., DeBlasio, A., and Mankin, A. S. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5641-5646). Erythromycin resistance was mediated by a specific interaction of the 23 S rRNA-encoded pentapeptide with the ribosome.
T, Tenson   +3 more
openaire   +2 more sources

MS²PIP: a tool for MS/MS peak intensity prediction [PDF]

open access: yes, 2013
Motivation: Tandem mass spectrometry provides the means tomatch mass spectrometry signal observations with the chemical entities that generated them. The technology produces signal spectra that contain information about the chemical dissociation pattern ...
Degroeve, Sven, Martens, Lennart
core   +2 more sources

Trinucleotide cassettes increase diversity of T7 phage-displayed peptide library

open access: yesBMC Biotechnology, 2007
Background Amino acid sequence diversity is introduced into a phage-displayed peptide library by randomizing library oligonucleotide DNA. We recently evaluated the diversity of peptide libraries displayed on T7 lytic phage and M13 filamentous phage and ...
McMahon James B   +4 more
doaj   +1 more source

Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]

open access: yes, 2007
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Alicia Aguilar   +54 more
core   +1 more source

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