Results 41 to 50 of about 254,967 (163)

Biological conduits combining bone marrow mesenchymal stem cells and extracellular matrix to treat long-segment sciatic nerve defects

open access: yesNeural Regeneration Research, 2015
The transplantation of polylactic glycolic acid conduits combining bone marrow mesenchymal stem cells and extracellular matrix gel for the repair of sciatic nerve injury is effective in some respects, but few data comparing the biomechanical factors ...
Yang Wang   +4 more
doaj   +1 more source

Biomathematical Description of Synthetic Peptide Libraries

open access: yesPLOS ONE, 2015
Libraries of randomised peptides displayed on phages or viral particles are essential tools in a wide spectrum of applications. However, there is only limited understanding of a library's fundamental dynamics and the influences of encoding schemes and sizes on their quality.
Sieber, Timo   +3 more
openaire   +5 more sources

Shrinkage of ipsilateral taste buds and hyperplasia of contralateral taste buds following chorda tympani nerve transection

open access: yesNeural Regeneration Research, 2015
The morphological changes that occur in the taste buds after denervation are not well understood in rats, especially in the contralateral tongue epithelium.
Yi-ke Li   +4 more
doaj   +1 more source

Matrilin-2, an extracellular adaptor protein, is needed for the regeneration of muscle, nerve and other tissues

open access: yesNeural Regeneration Research, 2015
The extracellular matrix (ECM) performs essential functions in the differentiation, maintenance and remodeling of tissues during development and regeneration, and it undergoes dynamic changes during remodeling concomitant to alterations in the cell-ECM ...
Éva Korpos, Ferenc Deák, Ibolya Kiss
doaj   +1 more source

Phage display: development of nanocarriers for targeted drug delivery to the brain

open access: yesNeural Regeneration Research, 2015
The blood brain barrier represents a formidable obstacle for the transport of most systematically administered neurodiagnostics and neurotherapeutics to the brain.
Babak Bakhshinejad   +2 more
doaj   +1 more source

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

open access: yesNature Communications, 2021
Many interactions between viral and host proteins are mediated by short peptide motifs. Here, using a phage-based viral peptide library, the authors identify 269 peptide-based interactions for 18 coronaviruses, including an interaction between SARS-CoV-2
Thomas Kruse   +21 more
doaj   +1 more source

Man-Made Synthetic Receptors for Capture and Analysis of Ochratoxin A

open access: yesToxins, 2015
Contemporary analytical methods have the sensitivity required for Ochratoxin A detection and quantification, but direct application of these methods on real samples can be rarely performed because of matrix complexity.
Claudio Baggiani   +2 more
doaj   +1 more source

A tailored tetravalent peptide displays dual functions to inhibit amyloid β production and aggregation

open access: yesCommunications Biology, 2023
Multivalent peptide library screens identify a tetravalent peptide that binds APP and A β via multivalent interactions and reduces A β in the brains of Alzheimer’s disease model mice.
Waka Sato   +15 more
doaj   +1 more source

Genetically Encoded Libraries of Nonstandard Peptides [PDF]

open access: yesJournal of Nucleic Acids, 2012
The presence of a nonproteinogenic moiety in a nonstandard peptide often improves the biological properties of the peptide. Non-standard peptide libraries are therefore used to obtain valuable molecules for biological, therapeutic, and diagnostic applications. Highly diverse non-standard peptide libraries can be generated by chemically or enzymatically
Takashi Kawakami, Hiroshi Murakami
openaire   +3 more sources

Using NGS to Uncover the Corruption of a Peptide Phage Display Selection

open access: yesCurrent Issues in Molecular Biology
Phage display has been widely used to identify peptides binding to a variety of biological targets. In the current work, we planned to select novel peptides targeting CD4 through screening of a commercial phage display library (New England Biolabs Ph.D ...
Danna Kamstrup Sell   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy