Results 31 to 40 of about 517,349 (290)

Osteogenic actions of the osteogenic growth peptide on bovine marrow mesenchymal stromal cells in culture

open access: yesVeterinární Medicína, 2008
The osteogenic growth peptide (OGP) regulates the differentiation of marrow mesenchymal stem cells derived from human and rodent cell lines into osteoblasts.
H.B. Zhu   +7 more
doaj   +1 more source

Molecular biology of natriuretic peptides and nitric oxide synthases [PDF]

open access: yesCardiovascular Research, 2001
Natriuretic peptides and nitric oxide play important roles in cardiovascular and renal physiology and disease. The natriuretic peptides - atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide - comprise a family of proteins that participate in the integrated control of intravascular volume and arterial blood pressure ...
openaire   +2 more sources

Modification of soybean sucrose synthase by S-thiolation with ENOD40 peptide A [PDF]

open access: yesBiochemical and Biophysical Research Communications, 2004
The gene ENOD40 is expressed at an early stage of root nodule organogenesis and has been postulated to play a central regulatory role in the Rhizobium-legume interaction. In vitro translation of soybean ENOD40 mRNA showed that the gene encodes two peptides of 12 and 24aa residues (peptides A and B) that bind to sucrose synthase.
Röhrig, H., John, M., Schmidt, J.
openaire   +3 more sources

Sphingolipid synthases of Toxoplasma gondii and other organisms

open access: yes, 2013
Toxoplasma gondii is an obligate intracellular protozoan parasite of the phylum Apicomplexa, and toxoplasmosis is an important disease in immuno-compromised individuals - especially AIDS patients, organ transplant recipients and patients receiving anti ...
Kannangara, N.
core   +4 more sources

Genome Mining Uncovers NRPS and PKS Clusters in Rothia dentocariosa with Inhibitory Activity against Neisseria Species

open access: yesAntibiotics, 2023
The growing global threat of antimicrobial resistance is reaching a crisis point as common bacterial infections, including those caused by pathogenic Neisseria species, are becoming increasingly untreatable. This is compelling the scientific community to
Elvis Achondou Akomoneh   +7 more
doaj   +1 more source

Thermodynamics of apocalmodulin and nitric oxide synthase II peptide interaction [PDF]

open access: yesFEBS Letters, 2004
The Ca2+‐free form of calmodulin (CaM), apocalmodulin (ApoCaM), regulates a variety of target proteins including nitric oxide synthase II (NOS‐II). The CaM‐binding site of NOS‐II can bind ApoCaM with high affinity. Substitution of hydrophobic amino acids by charged amino acids at crucial positions 3, 9 and 13 within the CaM‐binding motif did not ...
Censarek, Petra   +2 more
openaire   +2 more sources

The NarX-NarL two-component system regulates biofilm formation, natural product biosynthesis, and host-associated survival in Burkholderia pseudomallei

open access: yesScientific Reports, 2022
Burkholderia pseudomallei is a saprophytic bacterium endemic throughout the tropics causing severe disease in humans and animals. Environmental signals such as the accumulation of inorganic ions mediates the biofilm forming capabilities and survival of B.
Mihnea R. Mangalea, Bradley R. Borlee
doaj   +1 more source

Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases [PDF]

open access: yes, 2009
Background - There is an urgent need for the discovery and development of new drugs against Mycobacterium tuberculosis, the causative agent of tuberculosis, especially due to the recent emergence of multi-drug and extensively-drug resistant strains ...
Gurdyal S Besra   +19 more
core   +1 more source

Monomeric ATP Synthases

open access: yes, 2023
Monomeric ATP synthases exhibit a preference for curved lipid filaments. The curvatureseeking behavior relies on the membrane-mediated attractive interaction between rotating ATP synthases.
López Montero, Iván   +6 more
core   +1 more source

The Sound of Silence: Activating Silent Biosynthetic Gene Clusters in Marine Microorganisms

open access: yesMarine Drugs, 2015
Unlocking the rich harvest of marine microbial ecosystems has the potential to both safeguard the existence of our species for the future, while also presenting significant lifestyle benefits for commercial gain.
F. Jerry Reen   +3 more
doaj   +1 more source

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