Results 31 to 40 of about 627,325 (311)
Synthesis of Antimicrobial Lipopeptides Using the "CLipPA" Thiol-Ene Reaction.
, 2023 Cysteine Lipidation on a Peptide or Amino acid (CLipPA) technology provides a facile method for the lipidation of unprotected peptides containing a free thiol group by using a "click" radical-initiated thiol-ene reaction to effect addition to a vinyl ...
Brimble, Margaret A +3 more
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using Boc chemistry solid phase peptide synthesis
, 2020 Bovine pancreatic trypsin inhibitor (BPTI) is a well‐studied model for investigation of protein folding and stability. Here, we report the synthesis and characterization of wild‐type BPTI and a diastereomeric protein analogue [Gly37D‐Ala]BPTI.
Joanna Dowle +9 more
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Nature, 1949 Cook, Heilbron and Levy1 have recently prepared tetraglycylglycine and several di-peptides by reaction of 2-thio-5-thiazolones with amino-acid derivatives. During the past few years, much interest has also been shown in the polymerization potentialities of the N-carboxy anhydrides of α-amino-acids2–5.
openaire +2 more sources
An amalgamation of solid phase peptide synthesis and ribosomal peptide synthesis [PDF]
Peptide Science, 2008 AbstractExpressed protein ligation (EPL) is a protein semisynthesis technique that allows the site‐specific introduction of unnatural amino acids and biophysical probes into proteins. In the present study, we illustrate the utility of the approach through the generation of two semisynthetic proteins bearing spectroscopic probes. Dihydrofolate reductase
Jennifer J, Ottesen +3 more
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The Peptide Synthesis. II. Use of the Phenol Resin for the Peptide Synthesis [PDF]
Bulletin of the Chemical Society of Japan, 1968 Abstract The phenol resin is useful as support of the solid phase peptide synthesis. Its use is particularly advantageous for the synthesis of the N-protected peptide fragments, and those which have the intramolecular disulfide bond, such as oxytocin.
N, Inukai, K, Nakano, M, Murakami
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Recyclable hypervalent-iodine-mediated solid-phase peptide synthesis and cyclic peptide synthesis
Beilstein Journal of Organic Chemistry, 2018 The system of the hypervalent iodine(III) reagent FPID and (4-MeOC6H4)3P was successfully applied to solid-phase peptide synthesis and cyclic peptide synthesis.
Dan Liu, Ya-Li Guo, Jin Qu, Chi Zhang
doaj +1 more source
Study of the cellulose-peptide conjugation for the development of antimicrobial cotton textiles [PDF]
, 2022 openThe aim of this thesis is the study of chemoselective ligations in the context of antimicrobial tissues. Cotton is the chosen textile because it is a natural fiber, widely produced, air permeable and easy to functionalize.
ALBINI, FRANCESCA
core
A Rapid and Efficient Building Block Approach for Click Cyclization of Peptoids
Frontiers in Chemistry, 2020 Cyclic peptide-peptoid hybrids possess improved stability and selectivity over linear peptides and are thus better drug candidates. However, their synthesis is far from trivial and is usually difficult to automate.
Mamidi Samarasimhareddy +5 more
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Molecules, 2020 The high temperatures used in the production of milk may induce modifications in proteins structure. Due to occurrence of the Maillard reaction, lactose binds lysine residues in proteins, affecting the nutritional value.
Alessandra Gasparini +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source