Results 41 to 50 of about 3,503,980 (299)
A Rapid and Efficient Building Block Approach for Click Cyclization of Peptoids
Frontiers in Chemistry, 2020 Cyclic peptide-peptoid hybrids possess improved stability and selectivity over linear peptides and are thus better drug candidates. However, their synthesis is far from trivial and is usually difficult to automate.
Mamidi Samarasimhareddy +5 more
doaj +1 more source
Exploiting Conserved Quorum Sensing Signals in Streptococcus mutans and Streptococcus pneumoniae
Microorganisms, 2022 Bacterial species of the Streptococcus genera are considered either commensal bacteria or potential pathogens, according to their metabolic evolution and production of quorum sensing (QS)-controlled virulence factors. S. mutans, in particular, has become
Giulia Bernabè +6 more
doaj +1 more source
Solid Phase Peptide Synthesis: Analysis and Identification of Protein Kinase Substrates [PDF]
, 2005 This research study examines the synthesis of tyrosine containing peptides based on the protein paxillin. Paxillin is a proposed substrate of the Focal Adhesion Kinase (FAK) protein tyrosine kinase.
Kroodsma, Derrick
core
Study of the cellulose-peptide conjugation for the development of antimicrobial cotton textiles [PDF]
, 2022 openThe aim of this thesis is the study of chemoselective ligations in the context of antimicrobial tissues. Cotton is the chosen textile because it is a natural fiber, widely produced, air permeable and easy to functionalize.
ALBINI, FRANCESCA
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Influence of Disulfide Connectivity on Structure and Bioactivity of α-Conotoxin TxIA
Molecules, 2014 Cone snails express a sophisticated arsenal of small bioactive peptides known as conopeptides or conotoxins (CTxs). Through evolutionary selection, these peptides have gained the ability to interact with a range of ion channels and receptors, such as ...
Yong Wu +5 more
doaj +1 more source
The Peptide Synthesis. II. Use of the Phenol Resin for the Peptide Synthesis [PDF]
Bulletin of the Chemical Society of Japan, 1968 Abstract The phenol resin is useful as support of the solid phase peptide synthesis. Its use is particularly advantageous for the synthesis of the N-protected peptide fragments, and those which have the intramolecular disulfide bond, such as oxytocin.
N, Inukai, K, Nakano, M, Murakami
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Chemical synthesis of proteins: a tool for protein labeling [PDF]
, 2010 An ingenious stratagem useful to understand and modulate the structural and functional features of the proteins refers to the modification of their chemical structure.
De Rosa, Lucia
core +1 more source
Pharmaceutics, 2019 Nowadays, biomaterials are applied in many different branches of medicine. They significantly improve the patients’ comfort and quality of life, but also constitute a significant risk factor for biofilm-associated infections.
Malgorzata Anna Paduszynska +6 more
doaj +1 more source