Results 11 to 20 of about 3,503,980 (299)

Peptide Synthesis Using Unprotected Amino Acids [PDF]

open access: yes, 2023
The mandatory use of Nα-protecting group for amino acids, which invokes protection and deprotection operations and imposes a significant negative effect on environment sustainable development, constitutes the essential principle of peptide synthesis ...
Zejun, Peng, Tao, Liu, Junfeng, Zhao
core   +2 more sources

Design and synthesis of modified peptide antibiotics of the vancomycin family [PDF]

open access: yes, 2008
The ability of bacteria to constantly evolve new methods of resistance to antibacterial therapies represents a constant challenge in medicine. Emergence of strains of enterococci and S. Aureus that show resistance to vancomycin is an alarming phenomenon,
Bone, Philip Andrew
core   +7 more sources

Transcription of brain natriuretic peptide and atrial natriuretic peptide genes in human tissues [PDF]

open access: yes, 1994
We have compared the expression of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) genes in various human tissues using a quantitative polymerase chain reaction technique.
Nguyen, T.   +3 more
core   +2 more sources

Preparation, Characterization and In Vitro Stability of a Novel ACE-Inhibitory Peptide from Soybean Protein

open access: yesFoods, 2022
A soy protein isolate was hydrolyzed with Alcalase®, Flavourzyme® and their combination, and the resulting hydrolysates (A, F and A + F) were ultrafiltered and analyzed through SDS-PAGE.
Sara Sangiorgio   +11 more
doaj   +1 more source

Comparison of Three Xylose Pathways in Pseudomonas putida KT2440 for the Synthesis of Valuable Products

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Pseudomonas putida KT2440 is a well-established chassis in industrial biotechnology. To increase the substrate spectrum, we implemented three alternative xylose utilization pathways, namely the Isomerase, Weimberg, and Dahms pathways.
Isabel Bator   +8 more
doaj   +1 more source

Synthesis, Characterization and Evaluation of Peptide Nanostructures for Biomedical Applications

open access: yesMolecules, 2021
There is a challenging need for the development of new alternative nanostructures that can allow the coupling and/or encapsulation of therapeutic/diagnostic molecules while reducing their toxicity and improving their circulation and in-vivo targeting ...
Fanny d’Orlyé   +5 more
doaj   +1 more source

Peptide synthesis by recombinant Fasciola hepatica cathepsin L1 [PDF]

open access: yes, 2006
Synthesis of the tripeptide Z-Phe-Arg-SerNH2 has been accomplished by a recombinant cysteine protease, cathepsin L1 from liver fluke (Fasciola hepatica), using Z-Phe-Arg-OMe as acyl acceptor and SerNH2 as nucleophile in 0.1 M ammonium acetate pH 9.0–12.5%
Ruth, Deborah M.   +2 more
core   +1 more source

Fast Solution-Phase and Liquid-Phase Peptide Syntheses (SolPSS and LPPS) Mediated by Biomimetic Cyclic Propylphosphonic Anhydride (T3P®)

open access: yesMolecules, 2023
The growing applications of peptide-based therapeutics require the development of efficient protocols from the perspective of an industrial scale-up. T3P® (cyclic propylphosphonic anhydride) promotes amidation in the solution-phase through a biomimetic ...
Alexia Mattellone   +7 more
doaj   +1 more source

Introduction to Peptide Synthesis [PDF]

open access: yesCurrent Protocols in Protein Science, 2012
AbstractA number of synthetic peptides are significant commercial or pharmaceutical products, ranging from the dipeptide sugar substitute aspartame to clinically used hormones such as oxytocin, adrenocorticotropic hormone, and calcitonin. This unit provides an overview of the field of synthetic peptides and proteins.
Maciej, Stawikowski, Gregg B, Fields
openaire   +6 more sources

Substitution of D-Arginine at Position 11 of α-RgIA Potently Inhibits α7 Nicotinic Acetylcholine Receptor

open access: yesMarine Drugs, 2023
Conotoxins are a class of disulfide-rich peptides found in the venom of cone snails, which have attracted considerable attention in recent years due to their potent activity on ion channels and potential for therapeutics.
Yong Wu   +6 more
doaj   +1 more source

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