Results 11 to 20 of about 3,503,980 (299)
Peptide Synthesis Using Unprotected Amino Acids [PDF]
The mandatory use of Nα-protecting group for amino acids, which invokes protection and deprotection operations and imposes a significant negative effect on environment sustainable development, constitutes the essential principle of peptide synthesis ...
Zejun, Peng, Tao, Liu, Junfeng, Zhao
core +2 more sources
Design and synthesis of modified peptide antibiotics of the vancomycin family [PDF]
The ability of bacteria to constantly evolve new methods of resistance to antibacterial therapies represents a constant challenge in medicine. Emergence of strains of enterococci and S. Aureus that show resistance to vancomycin is an alarming phenomenon,
Bone, Philip Andrew
core +7 more sources
Transcription of brain natriuretic peptide and atrial natriuretic peptide genes in human tissues [PDF]
We have compared the expression of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) genes in various human tissues using a quantitative polymerase chain reaction technique.
Nguyen, T. +3 more
core +2 more sources
A soy protein isolate was hydrolyzed with Alcalase®, Flavourzyme® and their combination, and the resulting hydrolysates (A, F and A + F) were ultrafiltered and analyzed through SDS-PAGE.
Sara Sangiorgio +11 more
doaj +1 more source
Pseudomonas putida KT2440 is a well-established chassis in industrial biotechnology. To increase the substrate spectrum, we implemented three alternative xylose utilization pathways, namely the Isomerase, Weimberg, and Dahms pathways.
Isabel Bator +8 more
doaj +1 more source
Synthesis, Characterization and Evaluation of Peptide Nanostructures for Biomedical Applications
There is a challenging need for the development of new alternative nanostructures that can allow the coupling and/or encapsulation of therapeutic/diagnostic molecules while reducing their toxicity and improving their circulation and in-vivo targeting ...
Fanny d’Orlyé +5 more
doaj +1 more source
Peptide synthesis by recombinant Fasciola hepatica cathepsin L1 [PDF]
Synthesis of the tripeptide Z-Phe-Arg-SerNH2 has been accomplished by a recombinant cysteine protease, cathepsin L1 from liver fluke (Fasciola hepatica), using Z-Phe-Arg-OMe as acyl acceptor and SerNH2 as nucleophile in 0.1 M ammonium acetate pH 9.0–12.5%
Ruth, Deborah M. +2 more
core +1 more source
The growing applications of peptide-based therapeutics require the development of efficient protocols from the perspective of an industrial scale-up. T3P® (cyclic propylphosphonic anhydride) promotes amidation in the solution-phase through a biomimetic ...
Alexia Mattellone +7 more
doaj +1 more source
Introduction to Peptide Synthesis [PDF]
AbstractA number of synthetic peptides are significant commercial or pharmaceutical products, ranging from the dipeptide sugar substitute aspartame to clinically used hormones such as oxytocin, adrenocorticotropic hormone, and calcitonin. This unit provides an overview of the field of synthetic peptides and proteins.
Maciej, Stawikowski, Gregg B, Fields
openaire +6 more sources
Conotoxins are a class of disulfide-rich peptides found in the venom of cone snails, which have attracted considerable attention in recent years due to their potent activity on ion channels and potential for therapeutics.
Yong Wu +6 more
doaj +1 more source

