Results 21 to 30 of about 5,492 (203)

Ugi multicomponent reaction to prepare peptide–peptoid hybrid structures with diverse chemical functionalities [PDF]

open access: yes, 2018
Monodisperse sequenced peptides and peptoids present unique nano-structures based on their self-assembled secondary and tertiary structures. However, the generation of peptide and peptoid hybrid oligomers in a sequence-defined manner via Ugi ...
Azevedo, Helena S.   +12 more
core   +1 more source

A Peptoid-Based Fluorescent Sensor for Cyanide Detection

open access: yesMolecules, 2016
Peptoids, N-substituted glycine oligomers, are versatile peptidomimetics with diverse biomedical applications. However, strategies to the development of novel fluorescent peptoids as chemical sensors have not been extensively explored, yet.
Bumhee Lim, Jeeyeon Lee
doaj   +1 more source

Recent Advances in the Application Peptide and Peptoid in Diagnosis Biomarkers of Alzheimer’s Disease in Blood

open access: yesFrontiers in Molecular Neuroscience, 2021
Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases with irreversible damage of the brain and a continuous pathophysiological process.
Yuxin Guo   +6 more
doaj   +1 more source

Solid-Phase Synthesis of N-Substituted Glycine Oligomers (α‑Peptoids) and Derivatives

open access: yesMolecules, 2010
Peptoids (N-substituted polyglycines and extended peptoids with variant backbone amino-acid monomer units) are oligomeric synthetic polymers that are becoming a valuable molecular tool in the biosciences.
Rodney J. Ouellette, Adrian S. Culf
doaj   +1 more source

Click mediated synthesis of functionalized glycolipids with peptide-peptoid linkages [PDF]

open access: yesJournal of the Serbian Chemical Society, 2023
The present work describes the synthesis of a new class of glycolipids with systematic variations in the linkage region, as well as in the aglycon part using Cu(I) catalyzed click reaction.
Singhamahapatra Anadi   +5 more
doaj   +1 more source

Surface-immobilised antimicrobial peptoids [PDF]

open access: yesBiofouling, 2008
Surface modification techniques that create surfaces capable of killing adherent bacteria are promising solutions to infections associated with implantable medical devices. Antimicrobial (AM) peptoid oligomers (ampetoids) that were designed to mimic helical AM peptides were synthesised with a peptoid spacer chain to allow mobility and an adhesive ...
Andrea R, Statz   +4 more
openaire   +2 more sources

Peptoids with Antibiofilm Activity against the Gram Negative Obligate Anaerobe, Fusobacterium nucleatum

open access: yesMolecules, 2021
Peptoids (oligo N-substituted glycines) are peptide analogues, which can be designed to mimic host antimicrobial peptides, with the advantage that they are resistant to proteolytic degradation.
Jamie Toole   +5 more
doaj   +1 more source

Antifouling Glycocalyx-Mimetic Peptoids [PDF]

open access: yesJournal of the American Chemical Society, 2013
The glycocalyx of the cell is composed of highly hydrated saccharidic groups conjugated to protein and lipid cores. Although components of the glycocalyx are important in cell-cell interactions and other specific biological recognition events, a fundamental role of the glycocalyx is the inhibition of nonspecific interactions at the cell surface ...
Ham, Hyun Ok   +4 more
openaire   +4 more sources

Metalloporphyrin Dimers Bridged by a Peptoid Helix: Host-Guest Interaction and Chiral Recognition

open access: yesMolecules, 2018
Co-facial porphyrins have been designed to construct porphyrin tweezers with versatile molecular recognition capabilities. In this study, we synthesized metalloporphyrin⁻peptoid conjugates (MPPCs) displaying two metalloporphyrins on a peptoid ...
Yen Jea Lee, Boyeong Kang, Jiwon Seo
doaj   +1 more source

Structure–Function Relationship within Cu-Peptoid Electrocatalysts for Water Oxidation

open access: yesInorganics, 2023
Water oxidation (WO) is the first step in the water-splitting process aiming at the production of hydrogen as a green renewable fuel. To successfully perform WO, potent strategies for overcoming the high energetic barrier and slow kinetics of this ...
Guilin Ruan   +2 more
doaj   +1 more source

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