Results 41 to 50 of about 5,492 (203)
Antioxidants, 2023 Copper is an essential metal ion that is involved in critical cellular processes, but which can also exhibit toxic effects through its ability to catalyze reactive oxygen species (ROS) formation. Dysregulation of copper homeostasis has been implicated in
Anastasia Esther Behar, Galia Maayan
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Pharmaceuticals, 2012 Cell penetrating peptoids (CPPos) are potent mimics of the corresponding cell penetrating peptides (CPPs). The synthesis of diverse oligomeric libraries that display a variety of backbone scaffolds and side-chain appendages are a very promising source of
Dominik K. Kölmel +6 more
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Fluorogenic Substrates for In Situ Monitoring of Caspase-3 Activity in Live Cells. [PDF]
PLoS ONE, 2016 The in situ detection of caspase-3 activity has applications in the imaging and monitoring of multiple pathologies, notably cancer. A series of cell penetrating FRET-based fluorogenic substrates were designed and synthesised for the detection of caspase ...
Ana M Pérez-López +4 more
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Molecules, 2023 Nanotechnology has assumed a significant role over the last decade in the development of various technologies applied to health sciences. This becomes even more evident with its application in controlled drug delivery systems.
Thaissa Pasquali F. Rosalba +3 more
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100th Anniversary of Macromolecular Science Viewpoint: Opportunities in the Physics of Sequence-Defined Polymers [PDF]
, 2020 Polymer science has been driven by ever-increasing molecular complexity, as polymer synthesis expands an already-vast palette of chemical and architectural parameter space.
Perry, Sarah L., Sing, Charles E.
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2D Assemblies Based on a Tetraphenylethylene D,L‐Cyclic Peptide Scaffold
Angewandte Chemie, Volume 137, Issue 52, December 22, 2025.A new scaffold based on four nanotube‐forming cyclic peptide units attached to a tetraphenylethene (TPE) core with pH‐dependent self‐assembly that provides light‐emitting 2D nanosheets with controlled thickness is described. Abstract Two dimensional (2D) materials and aggregation‐induced emission (AIE) fluorophores have recently gained attention due to
Alfonso Bayón‐Fernández +7 more
wiley +2 more sources
Self-assembly of ultra-small micelles from amphiphilic lipopeptoids [PDF]
, 2017 Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca.
Aida +37 more
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Peptoids for biomaterials science [PDF]
Biomater. Sci., 2014 Reports of peptoid structures and interfaces highlighting their potential as synthetically convenient, multifunctional, modular and precisely tunable biomaterials are reviewed.
openaire +3 more sources
Addressing MRSA infection and antibacterial resistance with peptoid polymers
Nature Communications, 2021 Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacterial ...
Jiayang Xie +15 more
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The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus [PDF]
, 2013 BACKGROUND: The increase in antibiotic resistant bacteria has led to renewed interest in development of alternative antimicrobial compounds such as antimicrobial peptides (AMPs), either naturally-occurring or synthetically-derived.
Cohn, Marianne T +9 more
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