Results 71 to 80 of about 9,155,591 (249)

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Leadership, control at work, supervisor-subordinate guanxi and psychological ownership: A longitudinal study in China [PDF]

, 2014
The development of globalization in China has generated a growing number of Western organizations that engage in co-operations, joint ventures, or direct investments in this country.
Li, Tian
core  

Effect of perceived supervisor support, technological self-efficacy and technostress on nurses turnover intention: A moderated mediation model

Acta Psychologica
Drawing on the social exchange theory (SET), social cognitive career theory (SCCT) and the conservation of resources (COR) theory, this study aims to investigate the influence of perceived supervisor support on turnover intention among nurses in ...
Kazi Omar Siddiqi, Md. Hasanur Rahman, Junaid Rahman, Magdalena Radulescu   +3 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

AN INVESTIGATION ON RELATION AND PREDICTION OF PERCEIVED ORGANIZATIONAL SUPPORT (POS) ACCORDING TO 15 FOLD ORGANIZATIONAL VARIABLES [PDF]

Management & Marketing, 2012
The aim of this article is to study the relation between perceived organizational support(POS) with 15 fold variables including cooperation in decision making, servicing the public, job vision, trust to supervisor, satisfaction with salary, promotion ...
Hassan DARVISH, Mehdi ROOSTAEI, Hoda MOTEVALIAN   +2 more
doaj  

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Moderating Role of Agility in the Relationship between Perceived Organizational Support and Perceived Supervisor Support for Organizational Change at PT PLN (Persero)

, 2022
Aims: Change is something that every company must deal with on a regular basis. This is a critical issue for every company or organization. Today\u27s TUNA and VUCA organizational settings need adaptability and a learning culture.
Siddik, Aldio Fikri, Ahadiat, Ayi, Hayati, Keumala   +2 more
core   +1 more source

Support from below and above: The impact of perceived subordinate support, leader-member exchange, and perceived supervisor support on supervisor attitudes [PDF]

, 2020
Existing research indicates that perceived support is positively related to job performance and can influence perceptions of support by those with whom they interact.
Browder, Rachel
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Corporate Social Networks Effects on Perceived Organizational Support and Perceived Supervisor Support [PDF]

, 2011
Increasing use of online social network sites by organizations and their growing tendencies to establish an intraorganizationalsocial network necessitates academic attention as to how these social networks can affect organizationaloutcomes.
Vaezi, Reza
core