Results 81 to 90 of about 7,963,567 (288)

Bridging the Gap: Exploring Nursing Supervisor Support Influence on Nurses' Work Alienation and Deviant Behaviors [PDF]

Egyptian Journal of Health Care
Background: The strength of staff nurses' relationships with their supervisors may reduce both nurses' work alienation and their workplace deviant behaviors. Supervisor support is based on how the organization's agents perceive nurses to be treated. This
Azza Abdeldayem Ata, Manal Saleh Moustafa Saleh, Nesma Ahmed Kamel, Hanan Elsaid Elsabahy   +3 more
doaj   +1 more source

The role of perceived supervisor support and perceived organisational support on organisational citizenship behaviour in auxiliary police services at a public university: a pilot study [PDF]

Organizational citizenship behavior refers to voluntary actions that are not part of official duties and are not directly rewarded, but can increase the effectiveness of functions in the organization, such as helping colleagues and participating in extra
Ramdan, Mohamad Rohieszan, Mohd Fuzi, Nursyazwani, Ngah, Nor Syamaliah, Yee Ong, Sharon Yong, Seman, Mohamad Asri, Salleh, Mad Ithnin   +5 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Perceived Nursing Supervisor Support and Its Influence on Job Embeddedness among Staff Nurses [PDF]

Egyptian Journal of Health Care
Background: The quality of the relationship between nurses and their supervisors affects their embeddedness to the workplace, and eliminate their intention to leave it.
Naglaa Fathy Nomany Mohammed, Rabab Mahmoud Hassan, Samah Mohammed Elsayed   +2 more
doaj   +1 more source

Supervisor support as a double-edged sword: Supervisor emotion management accounts for the buffering and reverse-buffering effects of supervisor support

, 2018
Support is often proposed as a way in which supervisors can help employees cope with the negative impact of role stressors and other workplace demands (also referred to as the stress-buffering effect).
Jimmieson, Nerina L., Bordia, Prashant, Tucker, Michelle K.   +2 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Anger or pride? The effect of overqualification on employees’ first job behavior from the perspective of the proactive motivation model

Frontiers in Psychology
PurposeThis study investigates the relationship between perceived overqualification and proactive behaviors in the first job, focusing on the mediating roles of job anger and authentic pride and the moderating effect of perceived supervisor support.
Geng Li, Ziyi Zhang, Chunxin Zhang, Junqi Dou   +3 more
doaj   +1 more source

Motivation to Learn as a Mediator of the Relationship between Supervisor Support in Training Programs, Transfer of Competency and Job Performance [PDF]

This study was conducted in oder to measure the effect of the supervisor support and motivation to learn on employee outcomes (i.e., transfer of competency and job performance) using 100 usable questionnaires gathered from technical employees who have ...
Azman ISMAIL, Sofiah BONGOGOH, Sheela Chitra CHANDRA SEGARAN   +2 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source