Results 131 to 140 of about 13,212 (232)

Western blot for HA-Nazo Perilipin-2 interaction.

Lipid dyshomeostasis has been implicated in a variety of diseases ranging from obesity to neurodegenerative disorders such as Neurodegeneration with Brain Iron Accumulation (NBIA).
Neya More (17941479), Perinthottathil Sreejith (13751648), Rajnish Bharadwaj (17941482), Sara Lolo (17941470), Maduka Gunasinghe (17941476), Kristen R. Patten (17941473), Leo J. Pallanck (9291325)   +6 more
core   +1 more source

Perilipin is present in islets of Langerhans and protects against lipotoxicity when overexpressed in the {beta}-cell line INS-1

, 2009
Lipids have been shown to play a dual role in pancreatic beta-cells: a lipid-derived signal appears to be necessary for glucose-stimulated insulin secretion, whereas lipid accumulation causes impaired insulin secretion and apoptosis.
Londos, Constantine, Kimmel, Alan, LONDOS C, HOLM C., Xu, Guoheng, KIMMEL A, Holm, Cecilia, Klint, Cecilia, XU G, Sundler, Frank, Wierup, Nils, MARCHETTI, PIERO, BORG J, SUNDLER F, Borg, Jörgen, Larsson, Sara, LUPI R, Ström, Kristoffer, LARSSON S, STRÖM K, KLINT C, Lupi, Roberto, WIERUP N, Ström, Kristoffer,, Sundler, Frank,, Larsson, Sara,, Wierup, Nils,, Borg, Jörgen,, Holm, Cecilia,, Klint, Cecilia,, Lund University.   +30 more
core   +1 more source

Metabolic Adaptations in the Absence of Perilipin [PDF]

Journal of Biological Chemistry, 2004
Pradip K. Saha, Hideto Kojima, Javier Martinez-Botas, Agneta L. Sunehag, Lawrence Chan   +4 more
openaire   +1 more source

Depot-specific regulation of perilipin by rosiglitazone in a diabetic animal model.

, 2007
Treatment with rosiglitazone, a potent peroxisome proliferator–activated receptor (PPAR) γ agonist, results in lipid storage coupled with reduced release of free fatty acids into the circulation.
정태우, 차봉수, 안철우, 이현철, 강은석, Ahn, CW, Cha, BS, Lee, HC, Kim, HJ, Kang, ES, Lee, KW, Kim, DJ, Jung, TW   +12 more
core   +1 more source

Nazo, the Drosophila homolog of the NBIA-mutated protein-c19orf12, is required for triglyceride homeostasis.

PLoS Genetics
Lipid dyshomeostasis has been implicated in a variety of diseases ranging from obesity to neurodegenerative disorders such as Neurodegeneration with Brain Iron Accumulation (NBIA).
Perinthottathil Sreejith, Sara Lolo, Kristen R Patten, Maduka Gunasinghe, Neya More, Leo J Pallanck, Rajnish Bharadwaj   +6 more
doaj   +1 more source

Perilipin-2 [PDF]

, 2020
openaire   +1 more source

A Toll-like receptor 9-mediated pathway stimulates perilipin 3 (TIP47) expression and induces lipid accumulation in macrophages

, 2010
Excessive accumulation of lipids in macrophages results in formation of foam cells and is a hallmark of atherosclerosis. The PAT family of proteins has been implicated in this process, but details of their involvement in foam cell formation have not been
Wei-Li Zhong, Shoichiro Ikuyama, Di-Fei Wang, Jian-Qiu Gu, Xiao-Guang Yan, Jin Zhang, Bin Fan   +6 more
core   +1 more source

Distinct cellular pools of perilipin 5 point to roles in lipid trafficking

, 2011
The PAT family of lipid storage droplet proteins comprised five members, each of which has become an established regulator of cellular neutral lipid metabolism.
Erica Hlavin Bell (13812829), Erin L Miller (13812838), Taryn Summerfield (13812832), Zach P Niday (13812841), Leslie C Newman (13812835), Brian Patterson (1542691), John T Tansey (13812844), Sadie R Bartholomew (13812826), William Ackerman (10640894)   +8 more
core   +1 more source

Perilipin 5 (PLIN5) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Correction: Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish

eLife, 2023
Meredith H Wilson, Stephen C Ekker, Steven A Farber   +2 more
openaire   +2 more sources