Results 21 to 30 of about 3,695 (191)

Beta3Gn-T7 Is a Keratan Sulfate β1,3 N-Acetylglucosaminyltransferase in the Adult Brain

Frontiers in Neuroanatomy, 2022
Keratan sulfate (KS) glycan is covalently attached to a core protein of proteoglycans. KS is abundant in neuropils and presents densely in close proximity to the perineuronal region of the perineuronal net-positive neurons in the adult brain under ...
Yoshiko Takeda-Uchimura, Kazuchika Nishitsuji, Midori Ikezaki, Tomoya O. Akama, Yoshito Ihara, Fabrice Allain, Kenji Uchimura   +6 more
doaj   +1 more source

Parvalbumin interneuron alterations in stress-related mood disorders: A systematic review

Neurobiology of Stress, 2021
Stress-related psychiatric disorders including depression involve complex cellular and molecular changes in the brain, and GABAergic signaling dysfunction is increasingly implicated in the etiology of mood disorders.
George Perlman, Arnaud Tanti, Naguib Mechawar   +2 more
doaj   +1 more source

Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory [PDF]

, 2017
Chondroitin sulfate (CS) proteoglycans in perineuronal nets (PNNs) from the central nervous system (CNS) are involved in the control of plasticity and memory.
Foscarin, S, Raha-Chowdhury, R, Fawcett, JW, Kwok, JCF   +3 more
core   +4 more sources

Experience-dependent plasticity and modulation of growth regulatory molecules at central synapses. [PDF]

PLoS ONE, 2011
Structural remodeling or repair of neural circuits depends on the balance between intrinsic neuronal properties and regulatory cues present in the surrounding microenvironment.
Simona Foscarin, Danilo Ponchione, Ermira Pajaj, Ketty Leto, Maciej Gawlak, Grzegorz M Wilczynski, Ferdinando Rossi, Daniela Carulli   +7 more
doaj   +1 more source

TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults. [PDF]

, 2017
Brain damage due to stroke or traumatic brain injury (TBI), both leading causes of serious long-term disability, often leads to the development of epilepsy. Patients who develop post-injury epilepsy tend to have poor functional outcomes.
Becker, Albert, Friedman, Alon, Gu, Feng, Heinemann, Uwe, KAUFER, daniela, Kim, Soo, Lippmann, Kristina, Milikovsky, Dan, Morrissey, Christapher, Parada, Isabel, Prince, David, Senatorov, Vladimir, Vazquez, Oscar   +12 more
core   +5 more sources

Neurogenesis mediated plasticity is associated with reduced neuronal activity in CA1 during context fear memory retrieval

Scientific Reports, 2022
Postnatal hippocampal neurogenesis has been demonstrated to affect learning and memory in numerous ways. Several studies have now demonstrated that increased neurogenesis can induce forgetting of memories acquired prior to the manipulation of ...
Alexandria Evans, Dylan J. Terstege, Gavin A. Scott, Mio Tsutsui, Jonathan R. Epp   +4 more
doaj   +1 more source

A Sweet Talk: The Molecular Systems of Perineuronal Nets in Controlling Neuronal Communication [PDF]

, 2017
Perineuronal nets (PNNs) are mesh-like structures, composed of a hierarchical assembly of extracellular matrix molecules in the central nervous system (CNS), ensheathing neurons and regulating plasticity.
Arranz, Baig, Banerjee, Baranova, Barritt, Beebe, Beurdeley, Blosa, Bradbury, Brakebusch, Brückner, Brückner, Bukalo, Bukalo, Cabungcal, Caillard, Carstens, Carulli, Carulli, Carulli, Chang, Cheah, Corvetti, Coulson-Thomas, Dauth, Day, de Winter, Deepa, Deepa, Dick, Dityatev, Donato, Favuzzi, Foscarin, Frischknecht, Galtrey, Galtrey, Geissler, Giamanco, Gogolla, Grøndahl, Gu, Gurevicius, Happel, Heleen M. van 't Spijker, Hensch, Hisaoka, Hylin, Härtig, Härtig, Jansen, Jessica C. F. Kwok, Kochlamazashvili, Kwok, Kwok, Lafarga, Lander, Lee, Lensjø, Lensjø, Mabuchi, Matthews, McRae, Miyata, Miyata, Miyata, Morawski, Morawski, Morawski, Morikawa, Orlando, Pantazopoulos, Pelkey, Pizzorusso, Pizzorusso, Romberg, Rossier, Shinozaki, Smith, Spatazza, Spreafico, Steullet, Sugiyama, Suttkus, Suzuki, Vo, Wang, Yamada, Ye   +88 more
core   +2 more sources

Diverse functions of perineuronal nets

Acta Neurobiologiae Experimentalis, 2009
Perineuronal nets represent well-organised components of the extracellular matrix, which are surrounding cell bodies, dendrites, and axon segments of a particular class of neurones as well as forming lattice-like structures. The role of perineuronal nets is not fully elucidated yet.
Magdalena, Karetko, Jolanta, Skangiel-Kramska   +1 more
openaire   +2 more sources

Longitudinal in vivo imaging of perineuronal nets

Neurophotonics, 2023
Perineuronal nets (PNNs) are extracellular matrix structures implicated in learning, memory, information processing, synaptic plasticity, and neuroprotection. However, our understanding of mechanisms governing the evidently important contribution of PNNs to central nervous system function is lacking.
Benbenishty, Amit, Peled-Hajaj, Shany, Krishnaswamy, Venkat Raghavan, Har-Gil, Hagai, Havusha-Laufer, Sapir, Ruggiero, Antonella, Slutsky, Inna, Blinder, Pablo, Sagi, Irit   +8 more
openaire   +2 more sources

Environmental Enrichment From Birth Impacts Parvalbumin Expressing Cells and Wisteria Floribunda Agglutinin Labelled Peri-Neuronal Nets Within the Developing Murine Striatum

Frontiers in Neuroanatomy, 2019
Environmental enrichment can dramatically affect both the development and function of neural circuits. This is accomplished, at least in part, by the regulation of inhibitory cellular networks and related extracellular matrix glycoprotein structures ...
Angela May O’Connor, Thomas Joseph Burton, Hannan Mansuri, Gabriel Rhys Hand, Catherine Anne Leamey, Atomu Sawatari   +5 more
doaj   +1 more source