Results 41 to 50 of about 3,695 (191)
Dynamics of perineuronal nets over amphibian metamorphosis
Journal of Comparative Neurology, 2020 Abstract Extracellular matrix materials known as perineuronal nets (PNNs) have been shown to have remarkable consequences for the maturation of neural circuits and stabilization of behavior. It has been proposed that, due to the possibly long‐lived biochemical nature of their components, PNNs may be an important substrate by which ...
Jacob A. Edwards +2 more
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Brain Research Bulletin, 2022 Hyaluronan (HA) is a core constituent of perineuronal nets (PNNs) that surround subpopulations of neurones. The PNNs control synaptic stabilization in both the developing and adult central nervous system, and disruption of PNNs has shown to reactivate ...
Jana Dubisova +8 more
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Perineuronal nets: Cruise from a honeycomb to the safety nets
Brain Research Bulletin, 2022 The extracellular matrix (ECM) is a significant component of the brain, constituting up to 20 % of the brain volume and perform multifarious functions during development, maturation and regeneration of the central nervous system (CNS). ECM molecules assemble systematically to form a relatively rigid and unique lattice-like structure, known as ...
Urmilla John, Nisha Patro, Ishan Patro
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Perineuronal nets enhance the excitability of fast-spiking neurons [PDF]
, 2016 © The Author(s), 2016. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in eNeuro 3 (2016): e0112-16.2016, doi:10.1523/ENEURO.0112-16.2016.Perineuronal nets (PNNs) are ...
Balmer, Timothy
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The extracellular matrix and perineuronal nets in memory
Molecular Psychiatry, 2022 AbstractAll components of the CNS are surrounded by a diffuse extracellular matrix (ECM) containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate proteoglycans (HSPGs), hyaluronan, various glycoproteins including tenascins and thrombospondin, and many other molecules that are secreted into the ECM and bind to ECM components. In addition,
Fawcett, James W +5 more
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Chondroitin sulfates and their binding molecules in the central nervous system [PDF]
, 2017 Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in the central nervous system (CNS) matrix. Its sulfation and epimerization patterns give rise to different forms of CS, which enables it to interact specifically and with a ...
Djerbal, L, Kwok, JCF, Lortat-Jacob, H
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Proteoglycans in Perineuronal Nets.
ACTA HISTOCHEMICA ET CYTOCHEMICA, 1999 Proteoglycans are one of the major constituents of the extracellular matrix and cell membranes. In the brain, there are two major proteoglycans, chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. In the adult mammalian central nervous system, some species of chondroitin sulfate proteoglycan are localized in the ‘perineuronal net ...
Fumiko Matsui +2 more
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Hypothalamic Perineuronal Nets Are Regulated by Sex and Dietary Interventions
Frontiers in Physiology, 2021 Perineuronal nets (PNNs) are widely present in the hypothalamus, and are thought to provide physical protection and ion buffering for neurons and regulate their synaptic plasticity and intracellular signaling.
Nan Zhang +21 more
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Semaphorins in Adult Nervous System Plasticity and Disease
Frontiers in Synaptic Neuroscience, 2021 Semaphorins, originally discovered as guidance cues for developing axons, are involved in many processes that shape the nervous system during development, from neuronal proliferation and migration to neuritogenesis and synapse formation.
Daniela Carulli +3 more
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Molecular and cellular aspects of plasticity after neural injury [PDF]
, 2008 This review focuses on our effort to address plasticity of the nervous system after neural injury. We have used different animal models to examine cellular mechanisms of plasticity underlying the pathological and repair processes.
Chan, YS, Chen, LW, Shum, DKY, Yung, KKL
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