Results 51 to 60 of about 3,695 (191)

Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones [PDF]

, 2018
Perineuronal nets (PNNs) are extracellular matrix structures surrounding neuronal sub-populations throughout the central nervous system, regulating plasticity.
Asher, Jessica Kwok, Matthews, Mullen, Sian Irvine   +4 more
core   +2 more sources

The altered expression of perineuronal net elements during neural differentiation

Cellular & Molecular Biology Letters, 2018
Background Perineuronal nets (PNNs), which are localized around neurons during development, are specialized forms of neural extracellular matrix with neuroprotective and plasticity-regulating roles.
Nazli F. Eskici, Sevim Erdem-Ozdamar, Didem Dayangac-Erden   +2 more
doaj   +1 more source

Cocaine-induced plasticity in the cerebellum of sensitised mice [PDF]

, 2015
Rationale Prior research has accumulated a substantial amount of evidence on the ability of cocaine to produce short- and long-lasting molecular and structural plasticity in the corticostriatal-limbic circuitry. However, traditionally, the cerebellum
Carbó Gas, María, Carulli, Daniela, Cerezo García, Miguel, Gil-Miravet, Isis, Leto, Ketty, MIQUEL, MARTA, Rossi, Ferdinando, Sanchis-Segura, Carla, Vázquez Sanromán, Dolores   +8 more
core   +1 more source

Perineuronal Nets and Their Role in Synaptic Homeostasis [PDF]

International Journal of Molecular Sciences, 2019
Extracellular matrix (ECM) molecules that are released by neurons and glial cells form perineuronal nets (PNNs) and modulate many neuronal and glial functions. PNNs, whose structure is still not known in detail, surround cell bodies and dendrites, which leaves free space for synapses to come into contact.
Mateusz Bosiacki, Magdalena Gąssowska-Dobrowolska, Klaudyna Kojder, Marta Fabiańska, Dariusz Jeżewski, Izabela Gutowska, Anna Lubkowska   +6 more
openaire   +2 more sources

Spiny and Non-spiny Parvalbumin-Positive Hippocampal Interneurons Show Different Plastic Properties

Cell Reports, 2019
Summary: Dendritic spines control synaptic transmission and plasticity by augmenting post-synaptic potentials and providing biochemical compartmentalization.
Angelica Foggetti, Gilda Baccini, Philipp Arnold, Thomas Schiffelholz, Peer Wulff   +4 more
doaj   +1 more source

Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia. [PDF]

, 2017
Parvalbumin inhibitory interneurons (PVIs) are crucial for maintaining proper excitatory/inhibitory balance and high-frequency neuronal synchronization.
A A Grace, A Gokhale, A Kulak, A Reif, A-S LaMantia, AJ Sharp, AR Santos, AW Johnson, B Rodriguez-Santiago, B Zikopoulos, C Bernard, C Kaur, C Le Magueresse, CA Cea-Del Rio, CL Beasley, CZ Wang, D Mehta, DA Lewis, DA Rossignol, DJ Lodge, DT Balu, DW Meechan, E Rees, EK Lucas, F Donato, F Filice, F Fonnum, F Longordo, G Cellot, G Modinos, GC Carlson, GE Hardingham, GS Tomassy, H Hu, H Lin, H Morishita, H Morishita, H Morishita, H Stefansson, HA Fachim, HC Brenhouse, HE Stevens, I Garate, J Coyle, J Egea, J Flatow, J Hirrlinger, J Rossier, J-H Cabungcal, JB Savitz, JC Kwok, JH Cabungcal, JH Cabungcal, JH Cabungcal, JH Cabungcal, JK Yao, JM Boyce-Rustay, JM Long, JM Yang, JM Yang, JP Debost, JW Young, K Fejgin, K Gill, K Munkholm, K Q Do, K Sakimura, KQ Do, KQ Do, L Lindemann, L Xin, LJ Kobrynski, LS Callahan, M Cuenod, M Didriksen, M Inan, M Inan, M Komitova, M Puhl, M Tosic, M Yanagi, MA Benneyworth, MJ Gandal, MM Behrens, MM Behrens, MW Pitts, N Brunetti-Pierri, N Gass, N Gogolla, NC Brown, O Akyol, O Kann, O Penagarikano, O Penagarikano, O Yizhar, P Fazzari, P Gravina, P O'Donnell, P O'Donnell, P Steullet, P Steullet, P Steullet, PB Walter, PJ Uhlhaas, R Gysin, S Ben-Shachar, S Giovanoli, S Giovanoli, S Schiavone, SA Mauney, SB Powell, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SK Natarajan, SM Purcell, SY Kim, T Hikida, T K Hensch, T M Maynard, T Sakai, T Stojkovic, T Vaessen, The Dutch-Belgian Fragile X Consortium, TM Maynard, U Meyer, U Meyer, V Labrie, Y Goldshmit, Y Zhang, Z Jiang   +128 more
core   +2 more sources

The Role of Cerebellar Intrinsic Neuronal Excitability, Synaptic Plasticity, and Perineuronal Nets in Eyeblink Conditioning

Biology
Evidence is strong that, in addition to fine motor control, there is an important role for the cerebellum in cognition and emotion. The deep nuclei of the mammalian cerebellum also contain the highest density of perineural nets—mesh-like structures that ...
Bernard G. Schreurs, Deidre E. O’Dell, Desheng Wang   +2 more
doaj   +1 more source

Comparative analysis of the methods for quantitative study of the perineuronal net microstructure

Учёные записки Казанского университета: Серия Естественные науки, 2022
Perineuronal nets (PNN) are a special and highly structured type of the CNS extracellular matrix. In past few years, the important role of PNN in the normal physiology of the CNS and the changes in their expression associated with some pathologies have ...
N.S. Lipachev, A.S. Dvoeglazova, A.A. Sadreeva, A.V. Aganov, M.N. Paveliev   +4 more
doaj   +1 more source

Fast oscillatory activity in the anterior cingulate cortex: dopaminergic modulation and effect of perineuronal net loss. [PDF]

, 2014
Dopamine release in the prefrontal cortex plays a critical role in cognitive function such as working memory, attention and planning. Dopamine exerts complex modulation on excitability of pyramidal neurons and interneurons, and regulates excitatory and ...
Cabungcal, J.H., Cuénod, M., Do, K.Q., Steullet, P.   +3 more
core   +1 more source

Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory

Cell Reports, 2019
Summary: Adolescence is a vulnerable period characterized by major cognitive changes. The mechanisms underlying the emergence of new cognitive functions are poorly understood.
Soledad Domínguez, Christophe Clément Rey, Ludivine Therreau, Aurélien Fanton, Dominique Massotte, Laure Verret, Rebecca Ann Piskorowski, Vivien Chevaleyre   +7 more
doaj   +1 more source