Results 31 to 40 of about 136,012 (290)

IN-VITRO STUDIES ON CORTICOSTERONE PERMEATION THROUGH HAIRLESS MOUSE SKIN: ( PART I) [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2003
The use of penetration enhancer adjuvants was emerged as a growing trend intransdermal drug delivery. These adjuvants may reduce the capacity for drug binding to skinand promote the permeation of bimolecules through the skin.
Dalia. Shaker, Eman. El-leithy, Abdel Ghanem, Fahima Hashem   +3 more
doaj   +1 more source

A statistical experimental design approach to evaluate the influence of various penetration enhancers on transdermal drug delivery of buprenorphine

Journal of Advanced Research, 2015
A series of drug-in-adhesive transdermal drug delivery systems (patch) with different chemical penetration enhancers were designed to deliver drug through the skin as a site of application.
S.Mojtaba Taghizadeh, Ali Moghimi-Ardakani, Fatemeh Mohamadnia   +2 more
doaj   +1 more source

Gastrointestinal Permeation Enhancers for the Development of Oral Peptide Pharmaceuticals

Pharmaceuticals, 2022
Recently, two oral-administered peptide pharmaceuticals, semaglutide and octreotide, have been developed and are considered as a breakthrough in peptide and protein drug delivery system development.
Jae Cheon Kim, Eun Ji Park, Dong Hee Na
doaj   +1 more source

EFFECT OF PENETRATION ENHANCER ON THE IN VITRO EX VIVO PERMEATION OF DICLOFENAC GEL [PDF]

, 2014
  Objective: The objective of this study was to compare and evaluate in vitro ex vivo transdermal potential of the diclofenac sodium (DS) gel by different permeation enhancers using Franz-type diffusion cells.Methods: DS gel was prepared with carbapol,
Gurjar, Mukund, Shinde, Mukesh, Pimple, Shrikant, Shah, Mahesh, Gharge, Vikram   +4 more
core   +1 more source

Meloxicam transdermal delivery: effect of eutectic point on the rate and extent of skin permeation [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s):Drug delivery through the skin can transfer therapeutic levels of drugs for pharmacological effects. Analgesics such as NSAIDs have gastrointestinal side effects and topical dosage forms of these drugs are mainly preferred, especially for ...
Soliman Mohammadi-Samani, Gholamhossein Yousefi, Farhad Mohammadi, Fatemeh Ahmadi   +3 more
doaj  

Synergistic effect of iontophoresis and chemical enhancers on transdermal permeation of tolterodine tartrate for the treatment of overactive bladder

International Brazilian Journal of Urology, 2013
Purpose The objective of the study was to evaluate the synergistic transdermal permeation effect of chemical enhancers and iontophoresis technique on tolterodine tartrate (TT) transdermal gel and to evaluate its pharmacokinetic properties.
D. Prasanthi, P. K. Lakshmi
doaj   +1 more source

Combination of Cellulose Derivatives and Chitosan-Based Polymers to Investigate the Effect of Permeation Enhancers Added to In Situ Nasal Gels for the Controlled Release of Loratadine and Chlorpheniramine

, 2023
The purpose of the study is to develop and assess mucoadhesive in situ nasal gel formulations of loratadine and chlorpheniramine maleate to advance the bioavailability of the drug as compared to its conventional dosage forms.
Prasanth Viswanadhan Vasantha, Sandhya Murali, Prawez Alam, Sheri Peedikayil Sherafudeen, Sam Thomarayil Mathew, Mohamed Rahamathulla, Sultan Alshehri, Faiyaz Shakeel, Ala Yahya Sirhan, Bhageerathy Anantha Narayana Iyer, Sherafudeen, Sheri Peedikayil, Shakeel, Faiyaz, Sirhan, Ala Yahya, Rahamathulla, Mohamed, Narayana Iyer, Bhageerathy Anantha, Murali, Sandhya, Alam, Prawez, Alshehri, Sultan, Mathew, Sam Thomarayil, Viswanadhan Vasantha, Prasanth   +19 more
core   +1 more source

Multiple sequence-specific transcription factors modulate cytomegalovirus enhancer activity in vitro [PDF]

, 1988
The possibility of DNA-binding proteins interacting in vitro with the polymerase II transcriptional machinery was explored by using a competition assay with individual target sequences for enhancer-binding factors.
Lubon, H, Lubon, Henryk, Hennighausen, L, Hennighausen, Lothar, Ghazal, Peter, Ghazal, P   +5 more
core   +1 more source

Synthesis and in vitro characterization of chlorpheneramine-laden liposomes for topical applications

Pakistan Journal of Pharmaceutical Sciences, 2021
This study was aimed at synthesizing liposomes for the topical delivery of chlorpheneramine maleate using three-level factorial design. Each experiment consisted of a varying proportion of cholesterol, lecithin and a permeation enhancer mixture of ...
Urooj Afreen, Syed Nisar Hussain Shah, Rabia Aslam, Yasir Mehmood, Talib Hussain, Abid Mehmood Yousaf, Yasser Shahzad Saffron Pharmaceutical Pvt. Ltd, Faisalabad, Pakistan   +8 more
doaj   +1 more source

Surfactant and temperature effects on paraben transport through silicone membranes [PDF]

, 2013
This study investigates the effects of two surfactants (one anionic and one non-ionic) and controlled modifications in temperature (298–323 K) on the permeation of two structurally similar compounds through a silicone membrane using a Franz diffusion ...
Bibi, Aisha, Mitchell, John C., Dennis, Laura, Waters, Laura J., Waters, Laura J.; id_orcid   +4 more
core   +1 more source