PHARMACEUTICAL WORLD OF PERMEATION ENHANCERS [PDF]
International Journal of Current Pharmaceutical Research, 2021 The drugs with poor solubility results in delayed absorption which consequently affects the bioavailability. There are many drugs which are having good therapeutic value but not used commercially because of this reason. The permeation enhancers are therefore being utilized to counter this problem.
MANISH KUMAR, DEEPAK PRASHAR
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Evaluation of copaiba oil as enhancer of ibuprofen skin permeation
Brazilian Journal of Pharmaceutical Sciences, 2022 The administration of medications on the skin through transcutaneous routes is a practice that has been used by mankind for millennia. Some studies have been reporting the use of terpenes and natural oils rich in terpenes as an enhancer of cutaneous ...
Rodrigo José Lupatini Nogueira +3 more
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Asian Journal of Pharmaceutical Sciences, 2014 The effect of tea tree oil (TTO), cumin oil (CO), rose oil (RO) and aloe vera oil (AVO) on the skin permeation of losartan potassium (LP) was investigated. In vitro skin permeation studies were carried out using rat skin. The mechanism of skin permeation
Indu Vashisth +3 more
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A Systematic Quantitative Evaluation of Permeation Enhancement Window: Transdermal Permeation Enhancing Dynamics Establishment and Molecular Mechanisms Characterization of Permeation Enhancer [PDF]
Journal of Pharmaceutical Sciences, 2022 At present, transdermal permeation enhancing dynamics studies on permeation enhancers are still limited. In this study, these dynamics were established based on the content of enhancer Plurol Oleique CC in skin (CPOCC) and the increment of drug permeation amount (ΔQ).
Jiuheng Ruan +5 more
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Topical Delivery of Niacinamide to Skin Using Hybrid Nanogels Enhances Photoprotection Effect
Pharmaceutics, 2021 Niacinamide (NIA) has been widely used in halting the features of ageing by acting as an antioxidant and preventing dehydration. NIA’s physicochemical properties suggest difficulties in surpassing the barrier imposed by the stratum corneum layer to reach
Renata Basto +4 more
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Enhanced skin permeation of small molecules via retention of enhancer substances in matrix-type transdermal patches [PDF]
, 2022 A long-standing approach to improve the transdermal drug permeation is to use chemical penetration enhancers. Those substances reduce the barrier properties of the skin, especially of the stratum corneum, and facilitate the transdermal permeation ...
Otterbach, Anna
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Iraqi Journal of Pharmaceutical Sciences, 2020 This study designed to prepare ultrafine apixaban (APX) o/w nanoemulsion (NE) based gel with droplet size below 50 nm as a good method for transdermal APX delivery without using permeation enhancer, alternatively, the formulation components itself act as
Mustafa R. Abdulbaqi, Nawal A.Rajab
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The Development of Transdermal Piroxicam Using HPMC Matrices With PVP K-30 as a Penetration Enhancer [PDF]
, 2006 The physicochemical properties such as solubility, partition coefficient, and membrane permeability of a drug are required for formulating and estimating drugs absorption that pass through biological membranes.
Aryani, Ni Luh Dewi
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Long‐term daily oral administration of intestinal permeation enhancers is safe and effective in mice
Bioengineering & Translational Medicine, 2023 Although protein drugs are powerful biologic therapeutics, they cannot be delivered orally because their large size and hydrophilicity limit their absorption across the intestinal epithelium.
Katherine C. Fein +6 more
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NATURAL PERMEATION ENHANCER FOR TRANSDERMAL DRUG DELIVERY SYSTEM AND PERMEATION EVALUATION: A REVIEW [PDF]
, 2017 The transdermal drug delivery route is evolving as a potential route due to its advantages of bypassing the hepatic first pass metabolism, decreased side effects and gastrointestinal effects, improve patience compliance as it is a pain-free self ...
Das, Asha, Ahmed, Abdul Baquee
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