Results 21 to 30 of about 136,012 (290)

Modelling the effect of mixture components on permeation through skin [PDF]

, 2010
A vehicle influences the concentration of penetrant within the membrane, affecting its diffusivity in the skin and rate of transport. Despite the huge amount of effort made for the understanding and modelling of the skin absorption of chemicals, a ...
E.G. Samaras, J.E. Riviere, Ghafourian, Taravat, Samaras, Eleftherios G., J E Riviere (16236797), E G Samaras (16236791), Riviere, Jim E., J.D. Brooks, Taravat Ghafourian (4466557), J D Brooks (16236794), Brooks, James D., T. Ghafourian   +11 more
core   +1 more source

Development and in vivo evaluation of intranasal formulations of parathyroid hormone (1-34)

Drug Delivery, 2021
For efficient intranasal transport of parathyroid hormone (1-34) [PTH(1-34)], there is a great medical need to investigate permeation enhancers for intranasal formulations. In this study, the development of PTH(1-34) intranasal formulations was conducted.
Dan Wang, Yimeng Du, Wenpeng Zhang, Xiaolu Han, Hui Zhang, Zengming Wang, Nan Liu, Meng Li, Xiang Gao, Xiaomei Zhuang, Jing Gao, Aiping Zheng   +11 more
doaj   +1 more source

Investigating the Potential of Transdermal Delivery of Avanafil Using Vitamin E-TPGS Based Mixed Micelles Loaded Films

Pharmaceutics, 2021
To avoid the first-pass metabolism of avanafil (AVA) and its altered absorption in the presence of food after oral administration, this study aimed to investigate the potential of TPGS-based mixed micelle (MM)-loaded film for transdermal delivery and the
Abdullah A. Alamoudi, Osama A. A. Ahmed, Khalid M. El-Say   +2 more
doaj   +1 more source

N,N,N-Trimethyl chitosan as a permeation enhancer for inhalation drug delivery: interaction with a model pulmonary surfactant [PDF]

, 2023
N,N,N-Trimethyl chitosan (TMC), a biocompatible and biodegradable derivative of chitosan, is currently used as a permeation enhancer to increase the translocation of drugs to the bloodstream in the lungs.
Borgne, Rémi Le, Szabová, Jana, Mravec, Filip, Kalina, Michal, Mokhtari, Mostafa, Berret, Jean-François, Le Borgne, Rémi   +6 more
core   +1 more source

Status of surfactants as penetration enhancers in transdermal drug delivery

Journal of Pharmacy and Bioallied Sciences, 2012
Surfactants are found in many existing therapeutic, cosmetic, and agro-chemical preparations. In recent years, surfactants have been employed to enhance the permeation rates of several drugs via transdermal route.
Iti Som, Kashish Bhatia, Mohd. Yasir
doaj   +1 more source

Permeability Enhancement of Methotrexate Transdermal Gel using Eucalyptus oil, Peppermint Oil and Olive Oil(Conference Paper )#

Iraqi Journal of Pharmaceutical Sciences, 2022
Objective: the idea of this study to improve transdermal permeability of Methotrexate using eucalyptus oil, olive oil and peppermint oil as enhancers. Method: eucalyptus oil (2% and 4%), peppermint oil (2% and 4%) and olive oil (2% and 4%) all used as ...
Jamal Ali Ashoor, Jinan M. Mohsin, Hussein Mohammed Mohsin, Basam W. Mahde, Mowafaq M. Gareeb   +4 more
doaj   +1 more source

A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus [PDF]

, 1985
A strong transcription enhancer was identified in the genomic DNA (235 kb) of human cytomegalovirus (HCMV), a ubiquitous and severe pathogen of the herpesvirus group.
Boshart, Michael, Schaffner, Walter, Weber, Frank, Jahn, Gerhard, Dorsch-Häsler, Karoline, Fleckenstein, Bernhard   +5 more
core   +1 more source

Effect of Piperine on Skin Permeation of Curcumin from a Bacterially Derived Cellulose-Composite Double-Layer Membrane for Transdermal Curcumin Delivery

Scientia Pharmaceutica, 2018
Curcumin is a naturally occurring substance with various pharmacological activities. It has not been developed as a drug because of its low bioavailability due to its low solubility and absorption. Piperine is a natural enhancer that is popularly used to
Chutima Jantarat, Pornpak Sirathanarun, Somruedee Boonmee, Wanida Meechoosin, Husna Wangpittaya   +4 more
doaj   +1 more source

Hyaluronan-Cholesterol Nanogels for the Enhancement of the Ocular Delivery of Therapeutics

Pharmaceutics, 2021
The anatomy and physiology of the eye strongly limit the bioavailability of locally administered drugs. The entrapment of therapeutics into nanocarriers represents an effective strategy for the topical treatment of several ocular disorders, as they may ...
Nicole Zoratto, Laura Forcina, Roberto Matassa, Luciana Mosca, Giuseppe Familiari, Antonio Musarò, Maurizio Mattei, Tommasina Coviello, Chiara Di Meo, Pietro Matricardi   +9 more
doaj   +1 more source

Comparative evaluation of effect of CUR and PEG-CUR (A) on solubility (B, C) antibacterial effect and (D) Cremophore as permeation enhancer for selection of ointment formulations.

, 2022
Comparative evaluation of effect of CUR and PEG-CUR (A) on solubility (B, C) antibacterial effect and (D) Cremophore as permeation enhancer for selection of ointment formulations.
Khalid Mahmood (259708), Nabeela Ameer (12368851), Hafiz Muhammad Abdur Rahman (12368857), Mubashir Aziz (11857016), Muhammad Hanif (1737865), Nasreen Ramzan (12368854), Qurat-ul-Ain Ahmad (3948437)   +6 more
core   +1 more source