Results 171 to 180 of about 95,453 (303)

The role of fluvoxamine in the treatment of endotoxin‐induced acute heart injury

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Cardiovascular diseases are among the most common health problems worldwide. Inflammation plays a critical role in the pathogenesis of various heart diseases. Lipopolysaccharides (LPS) trigger inflammatory mechanisms, leading to an inflammatory response.
Ilter Ilhan, Halil Aşcı, Muhammet Yusuf Tepebasi, Nursel Hasseyid, Melih Arlıoğlu, Özlem Özmen   +5 more
wiley   +1 more source

Glucosylceramide regulates depression through activating peroxisome proliferator-activated receptor gamma in dorsal striatum. [PDF]

Theranostics
Jiang L, He Y, Liu H, Zhang D, Dai Y, Bu Q, Shi Q, Duan H, Zhao Y, Li S, Han S, Zhou Y, Zhao Y, Qin F, Chen Y, Wang L, Li H, Liu C, Qin M, Kuang W, Zhang N, Zhao Y, Cen X.   +22 more
europepmc   +1 more source

Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging

Cancer Science, EarlyView.
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka, Shuhei Hirose, Yu Wang, Tomonori Yaguchi, Kenji Chamoto   +4 more
wiley   +1 more source

The Furan Fatty Acids 11M5 and 11D5 Can Act as Activators of Human Peroxisome Proliferator-Activated Receptor Gamma. [PDF]

Mol Nutr Food Res
Pospiech J, Caspi A, Vetter W, Kerem Z, Frank J, Kufer TA.   +5 more
europepmc   +1 more source

The involvement of peroxisome proliferator-activated receptor gamma (PPARγ) in anti-inflammatory activity of N-stearoylethanolamine. [PDF]

Heliyon, 2022
Kosiakova H, Berdyshev A, Dosenko V, Drevytska T, Herasymenko O, Hula N.   +5 more
europepmc   +1 more source

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

Clinical Genetics, EarlyView.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise, Benkirane‐Jessel Nadia, Anton Nicolas, Vandamme Thierry, Clauss François, Conzatti Guillaume   +5 more
wiley   +1 more source

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack. [PDF]

Cochrane Database Syst Rev, 2023
Liu J, Wang LN.
europepmc   +1 more source

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

Naringenin, a citrus flavanone, enhances browning and brown adipogenesis: Role of peroxisome proliferator-activated receptor gamma. [PDF]

Front Nutr, 2022
Bae J, Yang Y, Xu X, Flaherty J, Overby H, Hildreth K, Chen J, Wang S, Zhao L.   +8 more
europepmc   +1 more source

Peroxisome Proliferator‑Activated Receptor Gamma Coactivator‑1α Deficiency in Hippocampal Astrocytes Underlies Enhanced Fear Memory Retrieval in Male Posttraumatic Stress Disorder Model Mice. [PDF]

MedComm (2020)
Wang J, Chen X, Chen D, Yang S, Wang J, Chen M, Zhu G.   +6 more
europepmc   +1 more source