Results 171 to 180 of about 105,604 (235)

Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α). [PDF]

Eur J Histochem
Feng L, Lin Z, Tang Z, Zhu L, Xu S, Tan X, Wang X, Mai J, Tan Q.   +8 more
europepmc   +1 more source

Analysis of arsenic-modulated expression of hypothalamic estrogen receptor, thyroid receptor, and peroxisome proliferator-activated receptor gamma mRNA and simultaneous mitochondrial morphology and respiration rates in the mouse. [PDF]

PLoS One
Alymbaeva D, Szabo C, Jocsak G, Bartha T, Zsarnovszky A, Kovago C, Ondrasovicova S, Kiss DS.   +7 more
europepmc   +1 more source

Amelioration of Oxidative Stress in Rats with Chronic Obstructive Pulmonary Disease through Shenqi Huatan Decoction Activation of Peroxisome Proliferator-Activated Receptor Gamma-Mediated Activated Protein Kinase/Forkhead Transcription Factor O3a Signaling Pathway. [PDF]

Can Respir J
Chen J, Qiao W, Xue X, Li D, Zhang Y, Xie D, Wang J, Sun Y, Yang S, Yang Z.   +9 more
europepmc   +1 more source

Peroxisome Proliferator-Activated Receptor Gamma

, 2020
는 핵 Peroxisome proliferator-activated receptor (PPAR) 수용체단백질로서 세포의 분화와 발달 지방 대사에 관 , 여하는 전사인자로 알려져 있다. 이것은 일반적으로 레 티노이드 수용체 와 이형이 X (retinoid X receptor: RXR) 합체 를 이루어 가닥의 특정 반응부위 (heterodimer) DNA 와 결합되어 있다 (response element) .
Sugeun Im, Gyeong-Su Park
openaire   +2 more sources

Current Progress on Peroxisome Proliferator-activated Receptor Gamma Agonist as an Emerging Therapeutic Approach for the Treatment of Alzheimer's Disease: An Update

Current Neuropharmacology, 2019
Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder, characterized by the deposition of amyloid-β within the brain parenchyma resulting in a significant decline in cognitive functions.
Absarul Haque, Mohd Jahir Khan, Mohammad Ashafaq   +2 more
exaly   +2 more sources

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Regulation of lipid‐induced macrophage polarization through modulating peroxisome proliferator‐activated receptor‐gamma activity affects hepatic lipid metabolism via a Toll‐like receptor 4/NF‐κB signaling pathway

Journal of Gastroenterology and Hepatology, 2020
Chronic inflammation links closely to insulin resistance and lipid metabolism in nonalcoholic fatty liver disease (NAFLD). Macrophage M1 activation plays an important role in the initiation and continuing of pro‐inflammatory response of NAFLD.
Hui-Min Wu, Xi-Xi Ni, Qinyu Xu, Qi Wang, Xiao-Yun Li, J. Hua   +5 more
semanticscholar   +1 more source

Peroxisome proliferator-activated receptor gamma in osteoarthritis

Modern Rheumatology, 2010
Osteoarthritis (OA) is among the most prevalent chronic human health disorders and the most common form of arthritis. It is a leading cause of disability in developed countries. This disease is characterized by cartilage deterioration, synovitis, and remodeling of the subchondral bone.
Hassan, Fahmi, Johanne, Martel-Pelletier, Jean-Pierre, Pelletier, Mohit, Kapoor   +3 more
openaire   +2 more sources

Peroxisome proliferator-activated receptor gamma and the control of adipogenesis

Current Opinion in Lipidology, 1997
The adipose cell is now known to play a complex role in energy homeostasis, storing energy and signaling to other tissues concerning the state of energy balance. The past several years have seen an explosive increase in our knowledge of the transcriptional basis of adipocyte differentiation.
R P, Brun, J B, Kim, E, Hu, B M, Spiegelman   +3 more
openaire   +2 more sources

Dietary modulation of peroxisome proliferator-activated receptor gamma

Gut, 2008
Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that regulates intestinal inflammation. PPARγ is highly expressed in the colon and can be activated by various dietary ligands. A number of fatty acids such as polyunsaturated fatty acids or eicosanoids are considered as endogenous PPARγ activators.
R, Marion-Letellier, P, Déchelotte, M, Iacucci, S, Ghosh   +3 more
openaire   +2 more sources

The pleiotropic functions of peroxisome proliferator-activated receptor γ

Journal of Molecular Medicine, 2000
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors, initially described as molecular targets for synthetic compounds that induce peroxisome proliferation. PPARgamma is the best characterized of the PPARs. The heterodimer of PPARgamma with the retinoid X receptor (RXR) plays a crucial role in adipogenesis and insulin ...
Debril, Marie-Bernard, Renaud, Jean-Paul, Fajas, Lluis, Auwerx, Johan   +3 more
openaire   +3 more sources