Results 91 to 100 of about 3,408 (187)
Pertussis Vaccine Candidate Based on Outer Membrane Vesicles Derived From Biofilm Culture
Frontiers in Immunology, 2021 Outer membrane vesicles (OMV) derived from Bordetella pertussis—the etiologic agent of the resurgent disease called pertussis—are safe and effective in preventing bacterial colonization in the lungs of immunized mice.
Francisco Carriquiriborde +9 more
doaj +1 more source
Molecular basis for the folding of β-helical autotransporter passenger domains [PDF]
, 2018 Bacterial autotransporters comprise a C-terminal β-barrel domain, which must be correctly folded and inserted into the outer membrane to facilitate translocation of the N-terminal passenger domain to the cell exterior.
Henderson, IR +9 more
core +5 more sources
Microbiology and Immunology, Volume 68, Issue 2, Page 36-46, February 2024.Abstract The Gram‐negative pathogenic bacterium Bordetella bronchiseptica is a respiratory pathogen closely related to Bordetella pertussis, the causative agent of whooping cough. Despite sharing homologous virulence factors, B. bronchiseptica infects a broad range of mammalian hosts, including some experimental animals, whereas B.
Xingyan Ma +3 more
wiley +1 more source
Selective ligand recognition by a diversity-generating retroelement variable protein.
PLoS Biology, 2008 Diversity-generating retroelements (DGRs) recognize novel ligands through massive protein sequence variation, a property shared uniquely with the adaptive immune response. Little is known about how recognition is achieved by DGR variable proteins.
Jason L Miller +5 more
doaj +1 more source
A three-way comparative genomic analysis of Mannheimia haemolytica isolates [PDF]
, 2010 Background Mannhemia haemolytica is a Gram-negative bacterium and the principal etiological agent associated with bovine respiratory disease complex. They transform from a benign commensal to a deadly pathogen, during stress such as viral infection and ...
Paulraj K Lawrence +3 more
core +2 more sources
Recent advances and challenges in antigen engineering & vaccine development [PDF]
, 2014 textVaccines play a vital role in public health by preventing infectious disease across the globe. Vaccine formulations represent a weakened form of a microbe or toxin that is injected into the human body to elicit an immune response, generating ...
Kornahrens, William Joseph
core
Läkaköha nüüdisaegne diagnostika [PDF]
, 2012 Läkaköha täpne ja õigeaegne diagnoosimine on ka praegu väljakutse igale arstile, sest läkaköhavastane vaktsineerimine on oluliselt muutnud läkaköha epidemioloogiat ja sümptomatoloogiat.
Jõgi, Piia +3 more
core +2 more sources
Changes in the genomic content of circulating Bordetella pertussis strains isolated from the Netherlands, Sweden, Japan and Australia: adaptive evolution or drift? [PDF]
, 2010 Background Bordetella pertussis is the causative agent of human whooping cough (pertussis) and is particularly severe in infants. Despite worldwide vaccinations, whooping cough remains a public health problem.
Audrey J King +4 more
core +1 more source
Journal of Microbiology, Immunology and Infection, 2018 Background/Purpose: Although assessing the immunogenicity and protective efficacy of acellular pertussis (aP) vaccines via murine model studies faces limitations, preliminary assessments have been achieved by evaluating respiratory challenge and humoral ...
Dong Ho Huh +7 more
doaj +1 more source
Appearance of Bordetella pertussis Strains Not Expressing the Vaccine Antigen Pertactin in Finland [PDF]
Clinical and Vaccine Immunology, 2012 Despite extensive vaccinations, resurgence of pertussis has been reported in many countries ([9][1]). Recently, emergence of Bordetella pertussis isolates not expressing the vaccine antigen pertactin (Prn) or pertussis toxin was described in France, where surveillance of the clinical isolates ...
Barkoff, A-M +5 more
openaire +5 more sources