The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?
Journal of Periodontal Research, EarlyView.Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander +3 more
wiley +1 more source
Multi-Omic Analysis of Bacteriophage-Insensitive Mutants Reveals a Putative Role for the Rcs Two-Component Phosphorelay System in Phage Resistance Development in <i>Erwinia amylovora</i>. [PDF]
VirusesIbrahim N +9 more
europepmc +1 more source
Journal of Periodontal Research, EarlyView.Emerging evidence suggests that periodontal health is not simply the absence of disease, but the result of a dynamic interaction between biological resilience, healthy lifestyles, adaptive coping mechanisms, and supportive environments. This results in a strong sense of coherence, which is not only a psychological state but also a biological state ...
Bruno G. Loos +4 more
wiley +1 more source
[Adaptation of dysenteric phage to phage-resistant cultures].
Zhurnal mikrobiologii, epidemiologii i immunobiologii, 2010 openaire +1 more source
Augmenting phage therapy using green nanotechnology for promising infection control, wound healing and devoiding phage resistance in MDR Pseudomonas aeruginosa. [PDF]
Sci RepMani A +7 more
europepmc +1 more source
The Hna Phage Defence Protein: A DNA‐Stimulated Helicase With Cryptic Nuclease Activity
Molecular Microbiology, EarlyView.The Hna (Helicase‐nuclease Abi) phage defence system consists of a single protein and provides defence through abortive infection. We show that Hna's abortive infection response can be recreated in a heterologous host upon expression of phage single‐stranded DNA binding protein (SSB) and present a characterization of Hna's biochemical activity.
Leah M. Sather +3 more
wiley +1 more source
Molecular Microbiology, EarlyView.Screening 72,555 plasmid sequences reveals that intact CRISPR‐Cas systems are rare (1.03%) but strongly enriched in multireplicon and multi‐stressor resistance plasmids, with Type IV‐A as the dominant subtype. These findings implicate plasmid‐encoded CRISPR‐Cas as non‐randomly retained elements of structurally complex and high‐risk backbones.
Hannay Crystynah Almeida de Souza +4 more
wiley +1 more source
Exploring phage-host interactions in <i>Burkholderia cepacia</i> complex bacterium to reveal host factors and phage resistance genes using CRISPRi functional genomics and transcriptomics. [PDF]
Microbiol SpectrDiaz B +3 more
europepmc +1 more source
Plant Breeding, EarlyView.ABSTRACT The breeding of pear (Pyrus communis) cultivars that meet market requirements and are at the same time resistant to fire blight is a challenging task beacuse appropriate resistance donors are scarce. To identify valuable resistance sources, phenotypic screening and genetic characterization are indispensable.
Martin Maag +4 more
wiley +1 more source
Adaptive loss of tRNA gene expression leads to phage resistance in a marine Synechococcus cyanobacterium. [PDF]
Nat MicrobiolZborowsky S, Tahan R, Lindell D.
europepmc +1 more source