Results 21 to 30 of about 32,198 (216)
Primary data linked to the publication "Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid exchange at endoplasmic reticulum-phagosome contact sites" in Communications Biology Criado-Santos et al 2023.
Nunes-Hasler, Paula
core +1 more source
Primary data linked to the publication "Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid exchange at endoplasmic reticulum-phagosome contact sites" in Communications Biology Criado-Santos et al 2023. Archive 1 of 5 including Figures
Nunes-Hasler, Paula
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Actin-based phagosome motility
Despite abundant evidence of actin's involvement at the particle internalization stage of phagocytosis, little is known about whether phagosomes undergo the same type of actin-based motility as observed with endocytic vesicles or such intracellular ...
Frederick S. Southwick +5 more
core +1 more source
Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes
Phagocytes engulf unwanted particles into phagosomes that then fuse with lysosomes to degrade the enclosed particles. Ultimately, phagosomes must be recycled to help recover membrane resources that were consumed during phagocytosis and phagosome ...
Roberto Botelho (14518364) +8 more
core +1 more source
Phagosome-lysosome fusion plays an important role in the destruction of micro-organisms by phagocytic cells. Several approaches have been used to study the determinants of phagosome-lysosome fusion in mouse macrophages. Fusion can be assayed by electron microscopy using horseradish peroxidase or thorium dioxide as a marker for secondary lysosomes or by
Gabay, JE, Horwitz, MA, Cohn, ZA
openaire +4 more sources
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Molecular characterization of phagosomes.
The transformation of newly formed phagosomes into mature phagolysosomes is a process that involves a complex series of interactions between phagosomes and other vacuolar organelles. The machinery required by phagosomes to mediate these interactions is poorly understood.
Desjardins, M. +6 more
openaire +4 more sources
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li +7 more
wiley +1 more source

