Prohibitin 2 orchestrates long noncoding RNA and gene transcription to accelerate tumorigenesis
The spatial co-presence of aberrant long non-coding RNAs (lncRNAs) and abnormal coding genes contributes to malignancy development in various tumors. However, precise coordinated mechanisms underlying this phenomenon in tumorigenesis remains incompletely
Tianyi Ding +10 more
doaj +1 more source
GOLPH3 promotes glioma progression by enhancing PHB2-mediated autophagy.
Due to the hypoxia and nutrient deficiency microenvironment, malignant glioma exhibits high autophagy activity and autophagy plays a significant role in the occurrence and development of glioma. However, the potential molecular mechanism of autophagy in glioma remains unknown. In this study, we demonstrated that Golgi phosphorylation protein 3 (GOLPH3),
Kai, Wang +9 more
openaire +1 more source
Development and Application of a ReaxFF Reactive Force Field for Oxidative Dehydrogenation on Vanadium Oxide Catalysts [PDF]
We have developed a new ReaxFF reactive force field to describe accurately reactions of hydrocarbons with vanadium oxide catalysts. The ReaxFF force field parameters have been fit to a large quantum mechanics (QM) training set containing over 700 ...
Cheng, Mu-Jeng +5 more
core +1 more source
Ограничения к параметрам режима дальних электропередач с промежуточными системами по условиям статической устойчивости [PDF]
Уравнения малых колебаний синхронных машин записываются относительно параметров режима узловых точек, на которые они работают. Приращения параметров режима для остальных точек записываются из уравнений балансов активных и реактивных мощностей.
Борисов, Р. И.
core
Mitophagy Promotes Hair Regeneration by Activating Glutathione Metabolism
Mitophagy maintains tissue homeostasis by self-eliminating defective mitochondria through autophagy. How mitophagy regulates stem cell activity during hair regeneration remains unclear.
Dehuan Wang +23 more
doaj +1 more source
Phb1:Phb2 heterodimers in the mitochondria—beyond functional interdependence [PDF]
openaire +2 more sources
Abstract 056 | Role of prohibitin isoforms in mitochondrial function with aging and exercise
Skeletal muscle is a highly metabolic and adaptable tissue that is reliant on an adequately-sized pool of healthy mitochondria to sustain its function (1,2).
Sabrina Champsi
doaj +1 more source
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology [PDF]
PINK1 and Parkin mediate mitophagy, the cellular process that clears dysfunctional mitochondria. Mitophagy is regulated by mitochondrial dynamics, but the molecules linking these two processes remain poorly understood.
Chan, David C. +9 more
core
Bombyx mori cypovirus (BmCPV), a member of the Reoviridae family, is a well-established research model for double-stranded RNA (dsRNA) viruses with segmented genomes. Despite its small genome size, the coding potential of BmCPV remains largely unexplored.
Manman Cao +11 more
doaj +1 more source
Prohibitin 2/PHB2 in Parkin-mediated mitophagy: a potential therapeutic target for mitochondrial diseases [PDF]
Lu, He +3 more
openaire +2 more sources

