Results 61 to 70 of about 4,788 (163)
Cancer Medicine, 2018 Esophageal squamous cell carcinoma (ESCC) is the eighth cause of cancer‐related deaths worldwide. To screen potential biomarkers associated with early recurrence/metastasis (R/M) of ESCC patients after radical resection, ESCC patients were analyzed by a ...
Xu‐Wei Cai +9 more
doaj +1 more source
PHB2 SF-12 Osteoarthritis-Specific Health Index: Development And Validation
Value in Health, 1998 OBJECTIVE:To develop and validate SF-12 osteoarthritis-specific health index (SF-12 OASHI). METHODS:Patient data on SF-12 and six osteoarthritis (OP) clinical variables (physician and patient global assessments, pain intensity, knee pain on weight bearing and motion, time to walk 50 feet) at baseline and week, 6, from two placebo-controlled ...
Gandhi, SK +5 more
openaire +1 more source
Fish & Shellfish Immunology, 2020 Before we have reported lamprey PHB2 could enhance the cellular oxidative-stressed tolerance, here the aim was to explore its mechanisms. We used flow cytometry analysis to identify a Lampetra morii homologue of PHB2 (Lm-PHB2) that could significantly decrease the levels of ROS generation in HEK293T cells. According to confocal microscopy observations,
Shi, Ying +7 more
openaire +2 more sources
Scientific Reports, 2018 Prohibitin 2(PHB2) is a member of the SFPH trans-membrane family proteins. It is a highly conserved and functionally diverse protein that plays an important role in preserving the structure and function of the mitochondria.
Ying Shi +5 more
doaj +1 more source
Screening of a Protein-Protein Interaction Focused Library Targeting BIG3-PHB2 Interaction [PDF]
Biophysical Journal, 2016 Endocrine resistance is one of the most challenging problems in estrogen receptor alpha (ERα)-positive breast cancer. The transcriptional activity of ERα is controlled by several coregulators, including prohibitin-2 (PHB2). Because of its ability to repress the transcriptional activity of activated ERα, PHB2 is a promising antiproliferative agent.
Chigira, Takeru +2 more
openaire +1 more source
Oxidative Medicine and Cellular Longevity, 2022 Mitophagy and oxidative stress play important roles in Parkinson’s disease (PD). Dysregulated mitophagy exacerbates mitochondrial oxidative damage; however, the regulatory mechanism of mitophagy is unclear. Here, we provide a potential mechanistic link between c‐Abl, a nonreceptor tyrosine kinase, and mitophagy in PD progression.
Yongjiang Zhang +9 more
openaire +2 more sources
Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions [PDF]
Scientific Reports, 2014 Xanthohumol (XN) is a natural anticancer compound that inhibits the proliferation of oestrogen receptor-α (ERα)-positive breast cancer cells. However, the precise mechanism of the antitumour effects of XN on oestrogen (E2)-dependent cell growth, and especially its direct target molecule(s), remain(s) largely unknown.
Yoshimaru, Tetsuro +8 more
openaire +2 more sources
A Fully Distributed Opportunistic Network Coding Scheme for Cellular Relay Networks
, 2013 In this paper, we propose an opportunistic network coding (ONC) scheme in cellular relay networks, which operates depending on whether the relay decodes source messages successfully or not.
Zheng, Baoyu, Zhu, Jia, Zou, Yulong
core +1 more source
Epigenetic Modification Mechanisms Involved in Inflammation and Fibrosis in Renal Pathology [PDF]
, 2018 The growing incidence of obesity, hypertension, and diabetes, coupled with the aging of the population, is increasing the prevalence of renal diseases in our society. Chronic kidney disease (CKD) is characterized by persistent inflammation, fibrosis, and
Dolade, Nuria +8 more
core +2 more sources
Cell Death and Disease, 2022 The single nucleotide polymorphism (SNP) rs9679162 located on GALNT14 gene predicts therapeutic outcomes in patients with intermediate and advanced hepatocellular carcinoma (HCC), but the molecular mechanism remains unclear.
Yu-De Chu +3 more
doaj +1 more source