Results 61 to 70 of about 4,768 (180)
Cancer Medicine, 2018 Esophageal squamous cell carcinoma (ESCC) is the eighth cause of cancer‐related deaths worldwide. To screen potential biomarkers associated with early recurrence/metastasis (R/M) of ESCC patients after radical resection, ESCC patients were analyzed by a ...
Xu‐Wei Cai +9 more
doaj +1 more source
PHB2 SF-12 Osteoarthritis-Specific Health Index: Development And Validation
Value in Health, 1998 OBJECTIVE:To develop and validate SF-12 osteoarthritis-specific health index (SF-12 OASHI). METHODS:Patient data on SF-12 and six osteoarthritis (OP) clinical variables (physician and patient global assessments, pain intensity, knee pain on weight bearing and motion, time to walk 50 feet) at baseline and week, 6, from two placebo-controlled ...
Gandhi, SK +5 more
openaire +1 more source
Fish & Shellfish Immunology, 2020 Before we have reported lamprey PHB2 could enhance the cellular oxidative-stressed tolerance, here the aim was to explore its mechanisms. We used flow cytometry analysis to identify a Lampetra morii homologue of PHB2 (Lm-PHB2) that could significantly decrease the levels of ROS generation in HEK293T cells. According to confocal microscopy observations,
Shi, Ying +7 more
openaire +2 more sources
Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants
Advanced Science, EarlyView.In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao +12 more
wiley +1 more source
Scientific Reports, 2018 Prohibitin 2(PHB2) is a member of the SFPH trans-membrane family proteins. It is a highly conserved and functionally diverse protein that plays an important role in preserving the structure and function of the mitochondria.
Ying Shi +5 more
doaj +1 more source
Cell Death and Disease, 2022 The single nucleotide polymorphism (SNP) rs9679162 located on GALNT14 gene predicts therapeutic outcomes in patients with intermediate and advanced hepatocellular carcinoma (HCC), but the molecular mechanism remains unclear.
Yu-De Chu +3 more
doaj +1 more source
Screening of a Protein-Protein Interaction Focused Library Targeting BIG3-PHB2 Interaction [PDF]
Biophysical Journal, 2016 Endocrine resistance is one of the most challenging problems in estrogen receptor alpha (ERα)-positive breast cancer. The transcriptional activity of ERα is controlled by several coregulators, including prohibitin-2 (PHB2). Because of its ability to repress the transcriptional activity of activated ERα, PHB2 is a promising antiproliferative agent.
Chigira, Takeru +2 more
openaire +1 more source
Oxidative Medicine and Cellular Longevity, 2022 Mitophagy and oxidative stress play important roles in Parkinson’s disease (PD). Dysregulated mitophagy exacerbates mitochondrial oxidative damage; however, the regulatory mechanism of mitophagy is unclear. Here, we provide a potential mechanistic link between c‐Abl, a nonreceptor tyrosine kinase, and mitophagy in PD progression.
Yongjiang Zhang +9 more
openaire +2 more sources
Advanced Science, EarlyView.Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu +7 more
wiley +1 more source
A Fully Distributed Opportunistic Network Coding Scheme for Cellular Relay Networks
, 2013 In this paper, we propose an opportunistic network coding (ONC) scheme in cellular relay networks, which operates depending on whether the relay decodes source messages successfully or not.
Zheng, Baoyu, Zhu, Jia, Zou, Yulong
core +1 more source