Results 71 to 80 of about 4,117,752 (305)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The Effect of Rootstocks on the Peel Phenolic Compounds of Clementine Mandarin (Citrus clementina) [PDF]

Journal of Medicinal Plants and By-products, 2017
Studies have shown that phenolic compounds are important in human health.The purpose of this research was to examine the influence of rootstocks on phenolic compounds. The content of individual phenolic compounds in fruits was determined by HPLC.
Behzad Babazadeh Darjazi, Kamkar Jaimand
doaj  

The Interaction of Phenolic Compounds With Bacteria

Journal of Pharmacy and Pharmacology, 1959
Abstract The uptake of hexylresorcinol by suspensions of E. coli and the associated release of cellular constituents were examined using heat-killed and butanol-treated organisms. The effect of the addition of cetomacrogol to the system was evaluated in terms of the reduction in the extent of drug binding and the prevention of the ...
A H Beckett, S J Patki, Ann E Robinson
openaire   +1 more source

Characterization of Phenolic Compounds in Wine Lees [PDF]

Antioxidants, 2018
The effect of vinification techniques on phenolic compounds and antioxidant activity of wine lees are poorly understood. The present study investigated the antioxidant activity of white and red wine lees generated at early fermentation and during aging.
Ye Zhijing, Amin Shavandi, Roland Harrison, Alaa El-Din Bekhit   +3 more
openaire   +5 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

STUDY OF TAXONOMICAL AND IDENTIFICATION FROM SOME PHENOLIC FOR SOME PLANT SPECIES GROWING AT ATRUSH REGION NORTHERN IRAQ USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) [PDF]

Mesopotamia Journal of Agriculture, 2019
This study  was carried out in the laboratory of collage of agriculture and Forestry to identifying the  phenolic compounds for  ten kinds of  plants of the species used in plant identification, The crude lipid free extract was  prepared by using soxhlet
T. Al-Tikriti, Y. M Q . Al- alousy, . Y. S. Al-Naman   +2 more
doaj   +1 more source

HPLC Analysis of Phenolic Compounds and Flavonoids with Overlapping Peaks

Food Technology and Biotechnology, 2020
SUMMARY The identification and quantification of phenolic compounds and flavonoids in various natural food products is typically conducted using HPLC analysis. Their analysis is particularly complex since most natural food products contain a large number
L. Mizzi, Christina Chatzitzika, R. Gatt, V. Valdramidis   +3 more
semanticscholar   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Antimicrobial Phenolic Compounds from L

Natural Product Communications, 2009
Bioassay-guided fractionation of an ethyl acetate extract from the aerial parts of Anabasis aphylla , a Chenopodiaceous species widely distributed in the northwest of China, led to the isolation of six phenolic compounds, which were identified by means ...
Hua Du, Ye Wang, Xiaojiang Hao, Chun Li, Youliang Peng, Jihua Wang, Hao Liu, Ligang Zhou   +7 more
doaj   +1 more source