Results 11 to 20 of about 2,749 (174)

Physiological plasticity in zebra finch color varieties mitigates DNA damage under oxidative stress [PDF]

open access: yesiScience
Summary: Melanins are fundamental vertebrate pigments. Pheomelanin synthesis utilizes cysteine, a precursor for the antioxidant glutathione. Sustained pheomelanin synthesis may thus reduce cysteine availability for antioxidant defenses, resulting in a ...
Cristiana I. Marques   +7 more
doaj   +2 more sources

Pheomelanin pigment remnants mapped in fossils of an extinct mammal [PDF]

open access: yesNature Communications, 2019
Chemical imaging and spectroscopy have previously been used to identify eumelanin residue in fossils and infer dark coloration. Here, Manning and colleagues develop an approach to identify pheomelanin (red pigment) residues and ascertain their ...
Phillip L. Manning   +14 more
doaj   +6 more sources

Blocking ASIP to Protect MC1R Signaling and Mitigate Melanoma Risk: An In Silico Study [PDF]

open access: yesPharmaceuticals
Background: Melanin protects skin and hair from the effects of ultraviolet (UV) radiation damage, which contributes to all forms of skin cancer, including melanoma.
Farah Maarfi   +3 more
doaj   +2 more sources

Molecular insights into region-specific sexual dichromatism: Comparative transcriptome analysis of red cheek pigmentation in zebra finches. [PDF]

open access: yesPLoS Genetics
Feathers, the primary skin appendage covering the avian body, undergo dynamic phenotypic changes throughout a bird's life. Males and females of the same species can exhibit sexually dichromatic plumage colors which play a critical role in mating choice ...
Gee-Way Lin   +8 more
doaj   +2 more sources

Evaluation of guinea fowls by genetic markers of plumage color [PDF]

open access: yesBIO Web of Conferences, 2023
The work was carried out at LLC “Genofond” of the Moscow region on gray-speckled, Zagorsk white-breasted, blue and cream guinea fowls of the VNITIP selection.
Roiter Ykov, Degtyareva Olga
doaj   +1 more source

Five genetic variants explain over 70% of hair coat pheomelanin intensity variation in purebred and mixed breed domestic dogs.

open access: yesPLoS ONE, 2021
In mammals, the pigment molecule pheomelanin confers red and yellow color to hair, and the intensity of this coloration is caused by variation in the amount of pheomelanin.
Andrea J Slavney   +5 more
doaj   +1 more source

Variation in the Oxidative State of Collared Flycatcher (<i>Ficedula albicollis</i>) Nestlings and Its Association With Their Plumage Coloration. [PDF]

open access: yesEcol Evol
Plumage coloration is widely recognized as an important component in intraspecific communication. Our aim was to examine the variation of oxidative parameters and their associations with the coloration of two different nestling plumage traits in collared flycatchers (Ficedula albicollis).
Kőmüves G   +5 more
europepmc   +2 more sources

Differential Induction of Reactive Oxygen Species and Expression of Antioxidant Enzymes in Human Melanocytes Correlate with Melanin Content: Implications on the Response to Solar UV and Melanoma Susceptibility

open access: yesAntioxidants, 2022
Constitutive pigmentation determines the response to sun exposure and the risk for melanoma, an oxidative stress–driven tumor. Using primary cultures of human melanocytes, we compared the effects of constitutive pigmentation on their antioxidant response
Parth R. Upadhyay   +5 more
doaj   +1 more source

Spiny mice modulate eumelanin to pheomelanin ratio to achieve cryptic coloration in "evolution canyon," Israel. [PDF]

open access: yesPLoS ONE, 2010
Coat coloration in mammals is an explicit adaptation through natural selection. Camouflaging with the environment is the foremost evolutionary drive in explaining overall coloration. Decades of enquiries on this topic have been limited to repetitive coat
Natarajan Singaravelan   +5 more
doaj   +1 more source

A frame-shift mutation in COMTD1 is associated with impaired pheomelanin pigmentation in chicken.

open access: yesPLoS Genetics, 2023
The biochemical pathway regulating the synthesis of yellow/red pheomelanin is less well characterized than the synthesis of black/brown eumelanin. Inhibitor of gold (IG phenotype) is a plumage colour variant in chicken that provides an opportunity to ...
Huijuan Bi   +18 more
doaj   +1 more source

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