Results 101 to 110 of about 5,503 (166)

Gut Dysbiosis Serine-Glycine Metabolism and Glioblastoma: Exploring Therapeutic Opportunities. [PDF]

Cancers (Basel)
Mangano M, Ermio MC, Sciubba F, De Rosa M, D'A Lessandro G, Limatola C, Rosito M.   +6 more
europepmc   +1 more source

Phosphoglycerate dehydrogenase-mediated serine reprogramming aggravates macrophage hyperinflammation in murine Pseudomonas aeruginosa pneumonia. [PDF]

Nat Commun
Chen R, Zeng R, Shi M, Zhang G, Wang F, Yang Q, Jiang Y, Zhang Y, Li Y, Qu J.   +9 more
europepmc   +1 more source

PHGDH knockdown activates autophagic flux to suppress migration and invasion of gastric cancer cells. [PDF]

Transl Cancer Res
Li S, Cao Y, Xu W, Wang X, Li R, Huang J, Zhang H.   +6 more
europepmc   +1 more source

Screening of Natural Inhibitors from <i>Pleurotus ostreatus</i> against PHGDH for Enhancing Antiviral Innate Immunity through Mendelian Randomization, Machine Learning, Molecular Docking, Molecular Dynamics Simulation, and Binding Free Energy Calculation. [PDF]

ACS Omega
Xu S, Yang K.
europepmc   +1 more source

CRISPR-Based Gene Dependency Screens Reveal Mechanism of BRAF Inhibitor Resistance in Anaplastic Thyroid Cancer. [PDF]

Mol Carcinog
Noronha S, Liu Y, Geneti G, Li H, Wu X, Sun D, Gujar V, Furusawa T, Lobanov A, Cam M, Pal LR, Nair NU, Day CP, Ruppin E, Ghosh C, Hu J, Ramamoorthy B, Kumar S, Andresson T, Chan K, O'Neill M, Chari R, Pommier Y, Rivero JD, Weyemi U, Kebebew E, Boufraqech M.   +26 more
europepmc   +1 more source

2-Hydroxyglutarate in onco-pathway: a metabolic driver of proto-oncogene activation. [PDF]

Front Oncol
Thamim M, Dhabal D, Balamurali MM, Thirumoorthy K.   +3 more
europepmc   +1 more source

Exploring the key molecular mechanisms and immune microenvironment of oxidative stress-related pathways in pancreatic neuroendocrine tumor combining scRNA-seq and bulk RNA. [PDF]

Discov Oncol
Cai Z, Li J, Li T, Peng Q.
europepmc   +1 more source

SNHG12 drives gastric cancer progression by activating the Wnt/β-catenin-mediated serine synthesis pathway. [PDF]

J Transl Med
Zhang N, Li T, Wen K.
europepmc   +1 more source

Tumor metabolic adaptation induced by L-asparaginase reveals a vulnerability to PARP1/2 inhibitor in B-cell lymphomas. [PDF]

Nat Commun
Aussel A, Nemazanyy I, Vandenberghe A, Meola P, Dorat N, Paul R, Habbouche L, Exposito L, Nottet N, Petrilli V, Chiche E, Mounier N, Marchetti S, Chaveroux C, Ricci JE, Chiche J.   +15 more
europepmc   +1 more source

Metabolic remodeling and immune evasion in glioblastoma: a focus on serine and lipid networks. [PDF]

Front Oncol
Jiang D, Wang C, Zhao Y, Li Y.
europepmc   +1 more source