Results 121 to 130 of about 6,588 (185)

Targeting the noncanonical function of metabolic enzyme PHGDH in driving PD-L1 expression and cancer immune evasion. [PDF]

Cell Rep Med
Liu J, Wang W, Sun Y, Huang S, Borole A, Zheng H, Hu W, Feng Z.   +7 more
europepmc   +1 more source

Integrative analysis and functional validation identified palmitoylated PHGDH as a therapeutic target for colon adenocarcinoma. [PDF]

Cell Oncol (Dordr)
Song Y, Lin L, Liu D, Zhu M, Wang P, Li K, Li A, Chen K, Ye Z.   +8 more
europepmc   +1 more source

Regulation of PSAT1 and PHGDH by m6A in endocrine-resistant breast cancer cells. [PDF]

Biochim Biophys Acta Mol Basis Dis
Piell KM, Vallarta A, Wilt AE, Avila-Valdes BL, Sumlut MH, Goli N, Petri BJ, He L, Zhang X, Clem BF, Klinge CM.   +10 more
europepmc   +1 more source

PHGDH phosphorylation mediated by WNK1 serves as a dual marker of metabolic vulnerability and responsiveness to oxaliplatin treatment. [PDF]

Proc Natl Acad Sci U S A
Fang S, Jin G, Yan M, Song Y, Zhao S, Zhang C, Shao Y, Zhao K, Liu M, Wang Z, Jia X, Guo Q, Guo M, Wang M, Guo Z, Dong Z.   +15 more
europepmc   +1 more source

PHGDH mediated serine biosynthesis metabolism suppresses vascular calcification. [PDF]

Biol Direct
Tan L, Liu J, Shi R, Liu Y.
europepmc   +1 more source

Exercise Reprograms the Spatial Function of Phosphoglycerate Dehydrogenase of a Pathogenic Nuclear Transcription Factor (PHGDH): A Narrative Review. [PDF]

Metabolites
Yang D, Guo W, Guo L.
europepmc   +1 more source

Mechanical Loading Induces Distinct and Shared Responses in Endothelial and Muscle Cells and Reveals Exercise-Like Molecular Profiles. [PDF]

FASEB J
Mäntyselkä S, Niemi E, Ylä-Outinen L, Kolari K, Uusitalo-Kylmälä L, Ortega-Alonso A, Liimatainen RM, Fachada V, Permi P, Kalenius E, Hulmi JJ, Kivelä R.   +11 more
europepmc   +1 more source

Immunometabolism and rheumatic disease-advancing targeted therapies. [PDF]

EULAR Rheumatol Open
Boothby MR.
europepmc   +1 more source

Molecular mechanisms of transhydrogenase activity and allosteric regulation in eukaryotic type II PHGDH Ser33. [PDF]

Nat Commun
Perrone S, Cifuente JO, Mastrella L, Marina A, Marina A, Trastoy B, Becker-Kettern J, Conrotte JF, Alcaide-Jiménez A, Corzana F, Glaab E, Guerin ME, Linster CL.   +12 more
europepmc   +1 more source

Deciphering the Functional Mechanisms of eIF3f in Tumors and Exploring Targeted Therapies. [PDF]

Pharmacol Res Perspect
Hao Y, Shao J, Lian N, Bian M.
europepmc   +1 more source