Results 131 to 140 of about 8,290 (226)

Phosphoglycerate dehydrogenase (PHGDH) [PDF]

Science-Business eXchange, 2011
openaire   +3 more sources

Figure S4 from PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2α-Targeting Therapy for Renal Cell Carcinoma

, 2023
Hirofumi Yoshino, Nijiro Nohata, Kazutaka Miyamoto, Masaya Yonemori, Takashi Sakaguchi, Satoshi Sugita, Toshihiko Itesako, Satoshi Kofuji, Masayuki Nakagawa, Rajvir Dahiya, Hideki Enokida   +10 more
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PHGDH Inhibitor CBR‐5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β‐Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib [PDF]

, 2022
Xiaocui Zhang, Meige Sun, Yisheng Jiao, Bei Lin, Qing Yang   +4 more
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Data from RETRACTED: PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis

, 2023
Debangshu Samanta, Youngrok Park, Shaida A. Andrabi, Laura M. Shelton, Daniele M. Gilkes, Gregg L. Semenza   +5 more
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XPR1 downregulation inhibits hepatocellular carcinoma progression by suppressing serine metabolism

Redox Biology
Xenotropic and polytropic retrovirus receptor 1 (XPR1) is highly expressed in various tumors and is associated with poor clinical prognosis, making it a proposed therapeutic target for cancer. However, the mechanism of XPR1 in tumorigenesis, particularly
Zi-qiang Liao, Ze-ning Chen, Yang-feng Lv, Yuan-yuan Zhang, Zhi-xing Liu, Zhi-qiang Deng, Qing-rong Liang, Chun-bo Zhang, Qun Tang   +8 more
doaj   +1 more source

FBXO7 ubiquitinates PRMT1 to suppress serine synthesis and tumor growth in hepatocellular carcinoma

Nature Communications
Cancer cells are often addicted to serine synthesis to support growth. How serine synthesis is regulated in cancer is not well understood. We recently demonstrated protein arginine methyltransferase 1 (PRMT1) is upregulated in hepatocellular carcinoma ...
Li Luo, Xingyun Wu, Jiawu Fan, Lixia Dong, Mao Wang, Yan Zeng, Sijia Li, Wenyong Yang, Jingwen Jiang, Kui Wang   +9 more
doaj   +1 more source

Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer

, 2021
Rumi Itoyama, Noriko Yasuda‐Yoshihara, Fumimasa Kitamura, Tadahito Yasuda, Luke Bu, Atsuko Yonemura, Tomoyuki Uchihara, Kota Arima, Xichen Hu, Jun Zhang, Yuya Okamoto, Takahiko Akiyama, Kohei Yamashita, Yosuke Nakao, Toshihiko Yusa, Yuki Kitano, Takaaki Higashi, Tatsunori Miyata, Katsunori Imai, Hiromitsu Hayashi, Yo‐ichi Yamashita, Takumi Mikawa, Hiroshi Kondoh, Hideo Baba, Takatsugu Ishimoto   +24 more
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PHGDH Gene [PDF]

, 2020
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Blood triglyceride levels are associated with DNA methylation at the serine metabolism gene PHGDH [PDF]

, 2017
Vinh Trương, Siying Huang, Jessica Dennis, Mathieu Lemire, Nora Zwingerman, Dylan Aïssi, Irfahan Kassam, Claire Perret, Philip Wells, Pierre‐Emmanuel Morange, Michael D. Wilson, David‐Alexandre Trégouët, France Gagnon   +12 more
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PHGDH wt Allele [PDF]

, 2020
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