RNA-binding activity of PHGDH drives amyloid-beta production in a human brain organoid model of sporadic Alzheimer's disease. [PDF]
Chen J +6 more
europepmc +1 more source
The "serine code" of metabolic reprogramming: multidimensional roles of the serine synthesis pathway in tumors and novel breakthroughs for targeted therapy. [PDF]
Su P, Yang Y, Zheng H.
europepmc +1 more source
Phosphoglycerate dehydrogenase-mediated serine reprogramming aggravates macrophage hyperinflammation in murine Pseudomonas aeruginosa pneumonia. [PDF]
Chen R +9 more
europepmc +1 more source
PHGDH knockdown activates autophagic flux to suppress migration and invasion of gastric cancer cells. [PDF]
Li S +6 more
europepmc +1 more source
Screening of Natural Inhibitors from <i>Pleurotus ostreatus</i> against PHGDH for Enhancing Antiviral Innate Immunity through Mendelian Randomization, Machine Learning, Molecular Docking, Molecular Dynamics Simulation, and Binding Free Energy Calculation. [PDF]
Xu S, Yang K.
europepmc +1 more source
Exploring the key molecular mechanisms and immune microenvironment of oxidative stress-related pathways in pancreatic neuroendocrine tumor combining scRNA-seq and bulk RNA. [PDF]
Cai Z, Li J, Li T, Peng Q.
europepmc +1 more source
Metabolic remodeling and immune evasion in glioblastoma: a focus on serine and lipid networks. [PDF]
Jiang D, Wang C, Zhao Y, Li Y.
europepmc +1 more source
ΔNp63α drives serine synthesis to promote carboplatin resistance in NSCLC. [PDF]
Deng L +6 more
europepmc +1 more source

