Results 11 to 20 of about 837,784 (254)

Inositol metabolism as a broad-spectrum antiviral target [PDF]

Frontiers in Microbiology
Inositol plays many important roles in cellular processes through its various derivatives including phosphatidylinositol phosphates. Viruses use phosphatidylinositol phosphates for their replication in multiple processes including entry, formation of ...
Kunlakanya Jitobaom, Kunlakanya Jitobaom, Prasert Auewarakul, Prasert Auewarakul   +3 more
doaj   +2 more sources

Newly Synthesized Phosphatidylinositol Phosphates Are Required for Synaptic Norepinephrine but Not Glutamate or γ-Aminobutyric Acid (GABA) Release

Journal of Biological Chemistry, 1998
Newly synthesized phosphatidylinositol phosphates have been implicated in many membrane-trafficking reactions. They are essential for exocytosis of norepinephrine in PC12 cells and chromaffin cells, suggesting a function in membrane fusion.
Mikhail Khvotchev, Thomas Sudhof
exaly   +2 more sources

A novel OPHN1 variant associated with cyclic strabismus but in the absence of OPHN1 syndrome [PDF]

Scientific Reports
Cyclic strabismus is a rare form of strabismus whereby individuals experience the disease in a pattern of alternating days with or without strabismus in a circadian rhythm-dependent manner.
Sachiko Nishina, Satoshi Kofuji, Keiko Matsubara, Hazuki Anzai, Kyoko Hirakata, Yuya Hanazono, Yoshimi Okamoto-Uchida, Jun Hirayama, Nobutoshi Ito, Maki Fukami, Hiroshi Nishina   +10 more
doaj   +2 more sources

Metabolomic and lipidomic changes in heat-stressed chickpea seeds [PDF]

Frontiers in Plant Science
Extreme climate induced heat stress during the reproductive phase significantly reduces yield and seed quality in chickpea, a vital cool-season pulse crop.
Uday Chand Jha, Uday Chand Jha, Marilyn L. Warburton, Harsh Nayyar, Kadambot H. M. Siddique, P. V. Vara Prasad   +5 more
doaj   +2 more sources

A unified approach to unambiguous synthesis of the phosphatidylinositol-3-phosphates involved in intracellular signal transduction

Tetrahedron Letters, 1997
A unified approach to unambiguous synthesis of the phosphatidylinositol-3-phosphates involved in intracellular signalling is illustrated by the synthesis of 1 d -1-(1′,2′-dihexadecanoyl -sn- glycero-3′-phospho )-myo- inositol-3,4,5-trisphsphate .
S. Aneja, A. Parra, C. Stoenescu, Wen-Jin Xia, R. Aneja   +4 more
exaly   +2 more sources

Phosphatidylinositol 3‐phosphates—at the interface between cell signalling and membrane traffic

EMBO Journal, 2016
Andrea Marat, Volker Haucke
exaly   +2 more sources

Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates. [PDF]

Mol Pharmacol, 2009
Holinstat M, Preininger AM, Milne SB, Hudson WJ, Brown HA, Hamm HE.   +5 more
europepmc   +2 more sources

Insulin provokes co-ordinated increases in the synthesis of phosphatidylinositol, phosphatidylinositol phosphates and the phosphatidylinositol–glycan in BC3H-1 myocytes

Biochemical Journal, 1988
Standaert M L, Farese R V
exaly   +2 more sources

Carbachol causes rapid phosphodiesteratic cleavage of phosphatidylinositol 4,5-bisphosphate and accumulation of inositol phosphates in rabbit iris smooth muscle; prazosin inhibits noradrenaline- and ionophore A23187-stimulated accumulation of inositol phosphates

Biochemical Journal, 1984
R. A. Akhtar, A. Abdel‐Latif
exaly   +2 more sources

Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis [PDF]

Proceedings of the National Academy of Sciences, 2015
Significance Phagocytes are key to innate immunity, as they ingest, kill, and degrade foreign particles, such as microbes. Particle uptake results in the formation of phagosomes that eventually fuse with lysosomes, the main degradative compartments in cells.
Jeschke, Andreas, Zehethofer, Nicole, Lindner, Buko, Krupp, Jessica, Schwudke, Dominik, Haneburger, Ina, Jovic, Marko, Backer, Jonathan M, Balla, Tamas, Hilbi, Hubert, Haas, Albert   +10 more
openaire   +4 more sources