Results 11 to 20 of about 79,046 (379)

Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization.

PLoS ONE, 2021
Quantification of endogenous biomarkers in clinical studies requires careful evaluation of a number of assay performance parameters. Comparisons of absolute values from several clinical studies can enable retrospective analyses further elucidating the ...
Yue Huang, Ruipeng Mu, David Wen, Joseph S Grimsby, Meina Liang, Anton I Rosenbaum   +5 more
doaj   +2 more sources

The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans [PDF]

Journal of Hepatology, 2016
Non peer ...
Arola, Johanna, Hyotylainen, Tuulia, Leivonen , Marja, Luukkonen, Panu K., Oresic, Matej, Orho-Melander, Marju, Yki-Jarvinen, Hannele, Zhou, You   +7 more
core   +2 more sources

Resolution of intact phosphatidylinositols by argentation thin-layer chromatography

Journal of Lipid Research, 1971
An argentation thin-layer chromatographic method is described for the separation of intact phosphatidylinositols on the basis of the degree of unsaturation of their component fatty acids.
B.J. Holub, A. Kuksis
doaj   +2 more sources

Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis

ACS Infectious Diseases, 2022
One-fourth of the global human population is estimated to be infected with strains of the Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB). Using lipidomic approaches, we show that tuberculostearic acid (TSA)-containing
Julius Brandenburg, J. Heyckendorf, Franziska Marwitz, Nicole Zehethofer, Lara Linnemann, N. Gisch, H. Karaköse, M. Reimann, K. Kranzer, B. Kalsdorf, Patricia M Sánchez-Carballo, Michael Weinkauf, Verena Scholz, S. Malm, S. Homolka, K. Gaede, C. Herzmann, U. Schaible, Christoph Hölscher, N. Reiling, D. Schwudke   +20 more
semanticscholar   +1 more source

Regulation of Necroptosis by Phospholipids and Sphingolipids

Cells, 2020
Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage ...
Xuewei Zhang, Masaya Matsuda, Nobuo Yaegashi, Takeshi Nabe, Kazuyuki Kitatani   +4 more
doaj   +1 more source

Maternal lipidomic signatures in relation to spontaneous preterm birth and large-for-gestational age neonates

Scientific Reports, 2021
Lipidome-wide metabolites may be useful biomarkers of pregnancy outcomes. We sought to characterize maternal lipidomic signatures associated with preterm birth and neonatal anthropometric parameters.
Max T. Aung, Pahriya Ashrap, Deborah J. Watkins, Bhramar Mukherjee, Zaira Rosario, Carmen M. Vélez-Vega, Akram N. Alshawabkeh, José F. Cordero, John D. Meeker   +8 more
doaj   +1 more source

Trained immunity or tolerance : opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors [PDF]

, 2014
Article Accepted Date: 29 January 2014. ACKNOWLEDGMENTS D.C.I. received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement HEALTH-2010-260338 (“Fungi in the setting of inflammation, allergy and autoimmune ...
Gow, Neil A R, Ifrim, Daniela C, Jacobs, Cor, Jacobs, Liesbeth, Jansen, Trees, Joosten, Leo A B, Netea, Mihai G, Quintin, Jessica, van der Meer, Jos W M, Williams, David L   +9 more
core   +8 more sources

Phosphoinositides signaling modulates microglial actin remodeling and phagocytosis in Alzheimer’s disease

Cell Communication and Signaling, 2021
Alzheimer’s disease is one of the neurodegenerative diseases, characterized by the accumulation of abnormal protein deposits, which disrupts signal transduction in neurons and other glia cells.
Smita Eknath Desale, Subashchandrabose Chinnathambi   +1 more
doaj   +1 more source

The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells. [PDF]

PLoS ONE, 2013
The ether-lipid precursor sn-1-O-hexadecylglycerol (HG) can be used to compensate for early metabolic defects in ether-lipid biosynthesis. To investigate a possible metabolic link between ether-linked phospholipids and the rest of the cellular lipidome ...
Jonas Bergan, Tore Skotland, Tuulia Sylvänne, Helena Simolin, Kim Ekroos, Kirsten Sandvig   +5 more
doaj   +1 more source

Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death

Metabolites, 2021
Caenorhabditis elegans is well-known as the model organism used to elucidate the genetic pathways underlying the first described form of regulated cell death, apoptosis. Since then, C.
Marcos A. Perez, Jennifer L. Watts
doaj   +1 more source