Results 11 to 20 of about 8,270 (191)
Oleic Acid-Containing Phosphatidylinositol Is a Blood Biomarker Candidate for SPG28
Biomedicines, 2023 Hereditary spastic paraplegia is a genetic neurological disorder characterized by spasticity of the lower limbs, and spastic paraplegia type 28 is one of its subtypes.
Takuya Morikawa +8 more
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Regulation of Necroptosis by Phospholipids and Sphingolipids
Cells, 2020 Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage ...
Xuewei Zhang +4 more
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Scientific Reports, 2021 Lipidome-wide metabolites may be useful biomarkers of pregnancy outcomes. We sought to characterize maternal lipidomic signatures associated with preterm birth and neonatal anthropometric parameters.
Max T. Aung +8 more
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Cell Communication and Signaling, 2021 Alzheimer’s disease is one of the neurodegenerative diseases, characterized by the accumulation of abnormal protein deposits, which disrupts signal transduction in neurons and other glia cells.
Smita Eknath Desale +1 more
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Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death
Metabolites, 2021 Caenorhabditis elegans is well-known as the model organism used to elucidate the genetic pathways underlying the first described form of regulated cell death, apoptosis. Since then, C.
Marcos A. Perez, Jennifer L. Watts
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BIOSYNTHESIS OF PHOSPHATIDYLINOSITOL [PDF]
Annals of the New York Academy of Sciences, 1970 Interest in our laboratory in the inositol lipids derives from the presence of relatively high amounts of phosphatidylinositol phosphate (PhIP) and phosphatidylinositol diphosphate (PhIPP) in excitable tissue. It was with this relationship in mind that we embarked on a study of biosynthetic pathways of inositol lipids several years ago. A first step in
Agranoff, Bernard W. +2 more
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Trained immunity or tolerance : opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors [PDF]
, 2014 Article Accepted Date: 29 January 2014. ACKNOWLEDGMENTS D.C.I. received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement HEALTH-2010-260338 (“Fungi in the setting of inflammation, allergy and autoimmune ...
Gow, Neil A R +9 more
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Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis
eLife, 2017 Phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] is essential for exocytosis. Classical ways of manipulating PI(4,5)P2 levels are slower than its metabolism, making it difficult to distinguish effects of PI(4,5)P2 from those of its metabolites.
Alexander M Walter +15 more
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The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells. [PDF]
PLoS ONE, 2013 The ether-lipid precursor sn-1-O-hexadecylglycerol (HG) can be used to compensate for early metabolic defects in ether-lipid biosynthesis. To investigate a possible metabolic link between ether-linked phospholipids and the rest of the cellular lipidome ...
Jonas Bergan +5 more
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Ion Mobility–Mass Spectrometry Approach for the Comparison of Sheep and Goat Milk Lipidomes
Applied Sciences, 2023 In this work, we report an analytical procedure to investigate the lipid compositions of sheep and goat milk. This approach is based on an ion mobility–high-resolution mass spectrometric method to facilitate the identification of complex lipid species ...
Cristina Manis +5 more
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