Results 41 to 50 of about 41,016 (180)

An assembly of proteins and lipid domains regulates transport of phosphatidylserine to phosphatidylserine decarboxylase 2 in Saccharomyces cerevisiae. [PDF]

J Biol Chem, 2014
Saccharomyces cerevisiae uses multiple biosynthetic pathways for the synthesis of phosphatidylethanolamine. One route involves the synthesis of phosphatidylserine (PtdSer) in the endoplasmic reticulum (ER), the transport of this lipid to endosomes, and decarboxylation by PtdSer decarboxylase 2 (Psd2p) to produce phosphatidylethanolamine.
Riekhof WR, Wu WI, Jones JL, Nikrad M, Chan MM, Loewen CJ, Voelker DR.   +6 more
europepmc   +4 more sources

An improved procedure for the synthesis of 14C-labeled phosphatidylserine from cerebral phosphatidic acid

Journal of Lipid Research, 1980
A complete procedure to prepare a highly labeled phosphatidyl-L-[U-14C]serine possessing the same fatty acid composition of brain phospholipids is reported. CDP-diglyceride was synthesized by reaction between phosphatidic acid and CMP-morpholidate as the
P Orlando, G Ippolito, L Binaglia, C Giordano, G Porcellati   +4 more
doaj   +1 more source

Cantharidin downregulates PSD1 expression and inhibits autophagic flux in yeast cells

FEBS Open Bio, 2022
Cantharidin is a terpenoid compound of insect origin, naturally produced by male blister beetles as an antipredatory mechanism. Cantharidin has anticancer properties, which are attributed to its ability to induce cell cycle arrest, DNA damage, MAPK ...
Swati Swagatika, Raghuvir Singh Tomar
doaj   +1 more source

Phosphatidylethanolamine positively regulates autophagy and longevity [PDF]

, 2015
This work was supported by the Austrian Science Fund FWF (grants LIPOTOX, I1000-B20, P23490-B12, and P24381-B20) to FM. The authors acknowledge support from NAWI Graz.
Pietrocola, F., Knittelfelder, O., O Knittelfelder, Franz, J, Pietrocola, F, Rockenfeller, Patrick, Carmona-Gutierrez, D., Madeo, F., Minois, N, Knittelfelder, O, J Franz, M Koska, Franz, J., Carmona-Gutierrez, D, G Kroemer, Madeo, F, Koska, M., Minois, N., Sica, V., Kroemer, G., F Pietrocola, Koska, M, D Carmona-Gutierrez, Kroemer, G, Rockenfeller, P, V Sica, F Madeo, N Minois, Rockenfeller, P., Sica, V, P Rockenfeller   +30 more
core   +1 more source

Vibrio cholerae proteome-wide screen for immunostimulatory proteins identifies phosphatidylserine decarboxylase as a novel Toll-like receptor 4 agonist. [PDF]

PLoS Pathogens, 2009
Recognition of conserved bacterial components provides immediate and efficient immune responses and plays a critical role in triggering antigen-specific adaptive immunity.
Ann Thanawastien, Wagner R Montor, Joshua Labaer, John J Mekalanos, Sang Sun Yoon   +4 more
doaj   +1 more source

Structure and mechanism of acetolactate decarboxylase [PDF]

, 2013
Acetolactate decarboxylase catalyzes the conversion of both enantiomers of acetolactate to the (R)-enantiomer of acetoin, via a mechanism that has been shown to involve a prior rearrangement of the non-natural (R)-enantiomer substrate to the natural (S ...
Victoria A. Marlow, Martin Wills, Wills, Martin, Dean Rea, Rea, Dean, Marlow, Victoria A., Vilmos Fülöp, Najmudin, Shabir, Fülöp, Vilmos, Shabir Najmudin   +9 more
core   +1 more source

Intracellular sites of lipid synthesis and the biogenesis of mitochondria

Journal of Lipid Research, 1972
Experimental data are presented on the intracellular localization in rat liver of three enzymes which are involved in the biosynthesis of phosphatidylethanolamine and diphosphatidylglycerol.
Edward A. Dennis, Eugene P. Kennedy
doaj   +1 more source

Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo [PDF]

, 2004
Strategies to enhance the immunogenicity of tumors are urgently needed. Although vaccination with irradiated dying lymphoma cells recruits a tumor-specific immune response, its efficiency as immunogen is poor.
Zimmermann, VS, Voll, Reinhard E., Turnay, Javier, Manfredi, Angelo A., Turnay, J, Dumitriu, IE, Voll, RE, Zimmermann, Valérie S, Angelo A. Manfredi, Bertling, Wolf, Rovere-Querini, P, Kalden, JR, Udo S. Gaipl, Herrmann, M, Attilio Bondanza, Gaipl, Udo S, Wolf Bertling, Bertling, W, Patrizia Rovere-Querini, Ingrid E. Dumitriu, Bondanza, Attilio, Stach, Christian M., Pöschl, E, Stach, Christian M, Gaipl, US, Javier Turnay, Herrmann, Martin, Martin Herrmann, Dumitriu, Ingrid E., Rovere-Querini, Patrizia, Christian M. Stach, Manfredi, Angelo A, Kalden, Joachim R, Valérie S. Zimmermann, Pöschl, Ernst, Stach, CM, Dumitriu, Ingrid E; id_orcid, Gaipl, Udo S., Joachim R. Kalden, Bondanza, A, Zimmermann, Valérie S., Voll, Reinhard E, Kalden, Joachim R., Reinhard E. Voll, Manfredi, AA, Ernst Pöschl, Dumitriu IE, Kalden JR, Bertling W, Turnay J, Herrmann M., Poschl E, Zimmermann VS, Gaipl US, Stach CM, Voll RE, BONDANZA , ATTILIO, ROVERE QUERINI , PATRIZIA, MANFREDI , ANGELO ANDREA M. A.   +58 more
core   +1 more source

Comparative transcriptomic and lipidomic analyses indicate that cold stress enhanced the production of the long C18–C22 polyunsaturated fatty acids in Aurantiochytrium sp.

Frontiers in Microbiology, 2022
Aurantiochytrium sp. belonging to Thraustochytrids are known for their capacity to produce long-chain polyunsaturated fatty acids (PUFAs). However, effects of cold stress accompanied with staged-temperature control on the fatty acid metabolism in ...
Yingjie Song, Yingjie Song, Yingjie Song, Zhangli Hu, Zhangli Hu, Zheng Xiong, Shuangfei Li, Shuangfei Li, Wei Liu, Tian Tian, Xuewei Yang, Xuewei Yang   +11 more
doaj   +1 more source

On the mechanism of the mitochondrial decarboxylation of phosphatidylserine

, 1992
To study intramitochondrial phospholipid flow, radiolabeled phosphatidylserine was introduced into isolated rat liver mitochondria from donor vesicles through the action of a nonspecific lipid transfer protein.
Faber, B.C.G., Kruijff, de, B., Hovius, R., Brigot, B., Nicolaij, K.   +4 more
core   +2 more sources