The mechanism of pyridine hydrogenolysis on molybdenum-containing catalysts : IV. The conversion of piperidine [PDF]
, 1973 The conversion of piperidine was investigated on a CoO-MoO3-Al2O3 catalysts as a function of the temperature, reaction time, initial piperidine partial pressure and the hydrogen pressure.\ud \ud At 60 atm of hydrogen and conversions below 50% piperidine ...
Mars, P., Neyens, W.J., Sonnemans, J.
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Разработка и регистрация лекарственных средств, 2023 Introduction. The search for new, effective and safe pharmacologically active substances remains an urgent task in the field of pharmacy. Many compounds of the piperidine and morpholine series are widely used in medical practice and belong to an ...
A. E. Khamitova, D. A. Berillo
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Microwave-Assisted Synthesis and Evaluation of Antimicrobial Activity of 3-{3-(s-Aryl and s-Heteroaromatic)acryloyl}-2Hchromen-2-one Derivatives [PDF]
, 2010 The exploration of potential utilization of microwaves as an energy source for heterocyclic synthesis was herein investigated using condensation of 3-acetylcoumarin (1) with aromatic and heteroaromatic aldehydes to afford the corresponding aromatic ...
Ajani +47 more
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Switching the stereochemical outcome of 6-endo-trig cyclizations; Synthesis of 2,6-Cis-6-substituted 4-oxopipecolic acids [PDF]
, 2012 A base-mediated 6-endo-trig cyclization of readily accessible enone-derived α-amino acids has been developed for the direct synthesis of novel 2,6-cis-6- substituted-4-oxo-L-pipecolic acids. A range of aliphatic and aryl side chains were tolerated by
Agami C. +41 more
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Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage [PDF]
, 2008 Clerocidin (CL), a microbial diterpenoid, reacts with DNA via its epoxide group and stimulates DNA cleavage by type II DNA topoisomerases. The molecular basis of CL action is poorly understood.
Binaschi +34 more
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New developments in the synthesis of emicoron [PDF]
, 2018 This paper reports on the modification of two synthetic steps in the usual protocol used for obtaining EMICORON. EMICORON is a benzo[ghi]perylen-diimide, which was synthesized for the first time in our laboratory in 2012, and has shown to have in vivo ...
Bianco, Armandodoriano +5 more
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1-[(3-Nitrophenyl)(piperidin-1-yl)methyl]piperidine [PDF]
Acta Crystallographica Section E Structure Reports Online, 2012 In the crystal structure of the title compound, C17H25N3O2, one-dimensional chains are formed via intermolecular C—H...O hydrogen bonds along the a axis.
Zhe-Qin Wang, Yi Ma
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Frontiers in Pharmacology, 2022 Piperine and piperidine are the two major alkaloids extracted from black pepper (Piper nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2)5NH.
Sicon Mitra +8 more
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4-[4-(Piperidin-1-yl)piperidin-1-yl]benzonitrile [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 In the title compound, C(17)H(23)N(3), both piperidine rings adopt chair conformations. In the crystal packing, intermolecular C-H⋯N hydrogen bonds and C-H⋯π interactions are present.
Guo-bin Xu +3 more
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Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]
, 1987 Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
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