Results 161 to 170 of about 23,915 (334)

Integrating Enzymes with Photoredox Catalysis for Conversion of Nitriles into Fluorinated Products

open access: yesChemCatChem, EarlyView.
Herein, we describe a novel method for producing highly sought‐after fluorinated compounds through the integration of nitrilase enzymes and iridium photoredox catalysis in a convenient one‐pot reaction. Our chemo‐ biocatalytic methodology delivers a range of fluorinated and fluoroalkylated products from simple nitrile precursors, in good yields, at ...
Stuart Angiolini   +6 more
wiley   +1 more source

Functionalized Dialdehydes as Promising Scaffolds for Access to Heterocycles and beta-Amino Acids: Synthesis of Fluorinated Piperidine and Azepane Derivatives [PDF]

open access: yes, 2017
Functionalized dialdehydes are considered important substrates, which may be transformed into various substituted heterocycles, alicyclic and polysubstituted compounds.
Abrahami, Renata Anita   +3 more
core  

The Azidofunctionalization of Alkenes

open access: yesChemistryEurope, EarlyView.
The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
wiley   +1 more source

Synthesis of enantiopure trisubstituted piperidines from a chiral epoxyaziridine and α-amino esters [PDF]

open access: yes, 2009
Concellón Gracia, José Manuel   +2 more
core   +1 more source

Catalytic SuFEx Reactivity of Sulfonimidoyl Fluorides with Functionalized Amines with Automation Applicable Conditions

open access: yesChemistryEurope, EarlyView.
GA: Sulfonimidoyl fluorides react with a diverse set of amines in a HOBt‐catalyzed sulfur(VI) fluorine exchange reaction to access sulfonimidamides, including directly NH‐sulfonimidamides, and in an automated workflow. In addition, SNAr reactivity of 4‐fluoroaryl sulfonimidoyl fluorides is discovered and exploited to prepare complex sulfonimidoyl ...
Dominique Deans   +6 more
wiley   +1 more source

The stereochemistry of the addition of chlorotitanium enolates of N-acyl oxazolidin-2-ones to 5- and 6- membered N-acyliminium ions

open access: yesJournal of the Brazilian Chemical Society, 2001
The stereoselective addition of chiral and achiral titanium enolates derived from the corresponding N-acyl oxazolidin-2-ones to 5- and 6- membered N-acyliminium ions afforded 2-substituted pyrrolidines in moderate to good diastereoisomeric ratio (5:1 to ...
Pilli Ronaldo A.   +2 more
doaj  

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