Results 161 to 170 of about 40,506 (345)

Design of Potent Mannose‐6‐Phosphate Derivatives as Ligands for CI‐M6P/IGF2R Using Fluorescence Polarization Assay

Chemistry – A European Journal, EarlyView.
We designed and synthesized novel mannose‐6‐phosphate (M6P) derivatives to enhance their binding affinity for the CI‐M6P/IGF2 receptor, which plays a key role in lysosomal targeting. Using a fluorescence polarization assay, we evaluated di‐, tri‐, and penta‐M6P peptides and modified M6P analogs.
Lucie Mrázková, Klaudia Hladoníková, Barbora Toncarová, Michal Fischer, Jakub Zýka, Jaroslav Kozák, Michal Kráľ, Milan Kožíšek, Jiří Jiráček, Jakub Kaminský, Kamil Parkan, Lenka Žáková   +11 more
wiley   +1 more source

Derivatives of eis-NPCl₂(NSOCl)₂ and (NPCl₂)₂NSOCl, Part IX [1] Substitution Reactions of cis-NPCl₂(NSOCl)₂ with Piperidine [PDF]

, 1978
H. H. Baalmann, Ron J. Keizer, J. C. van de Grampel, C. Kruk   +3 more
openalex   +1 more source

Synthesis and crystal structure of piperidinyl propanenitrile towards the preparation of piperidine based bioactive films for drug delivery applications. [PDF]

Sci Rep
Mohamed-Ezzat RA, Hasanin MS, Kariuki BM, Dacrory S.   +3 more
europepmc   +1 more source

The Effect of Aldehyde and Carboxylic Acid Substitution on the Isomerization of Hemithioindigo Photoswitches

Chemistry – A European Journal, Volume 31, Issue 31, June 3, 2025.
The core of an HTI photoswitch with different oxidation states of the sulfur heteroatom was modified by introducing aldehydes and carboxylic acid substituents for tailored absorption, quantum yields, and thermal stability. Notably, the substituted HTIs enabled high isomerization yields, while sulfur oxidation enhanced quantum yields but reduces ...
Matías I. Quindt, Taegeun Jo, Amol Kumar, Jorn D. Steen, Luca D'Amario, Sascha Ott, Stefano Crespi   +6 more
wiley   +1 more source

Stereocontrolled synthesis of 3-hydroxy-2-piperidinone carboxamides by catalytic ring-opening aminolysis of bridged <i>δ</i>-lactam-γ-lactones. [PDF]

RSC Adv
Beng TK, Curry K, Gitonga A, Yu K, Edwards S.   +4 more
europepmc   +1 more source

Membran‐Bioreaktor‐Technik kombiniert mit nachgeschalteter Ozonung – Vergleich mit konventionellen Ozonanwendungen Combination of Membrane Bioreactor and Downstream Ozonation – A Comparison to Conventional Ozone Applications

Chemie Ingenieur Technik, EarlyView.
Kommunale Kläranlagen gelten als Haupteintragspfad organischer Mikroschadstoffe in die aquatische Umwelt. Ein Großteil der Arzneimittelrückstände und Industriechemikalien wird in Kläranlagen nicht oder nur teilweise entfernt. Um einen qualitativ höheren Kläranlagen‐Ablauf zu erzeugen, wird eine Kombination aus hybridem Teilstrom‐Membran‐Bioreaktor mit ...
Maximilian Werner, Jie Ji, Minyi Yin, Holger Lutze, Stefan Panglisch   +4 more
wiley   +1 more source

Syntheses of N-(Chlorobenzoylaminoalkyl)piperidines and N-(Chlorothiobenzoylaminoalkyl)piperidines

, 1969
去来川 覚三, 広瀬 拓治, 伏崎 弥三郎   +2 more
openalex   +2 more sources

Reductive Transamination of Pyridinium Salts to N-Aryl Piperidines. [PDF]

J Org Chem
Chen Z, Song G, Qi L, Gunasekar R, Aïssa C, Robertson C, Steiner A, Xue D, Xiao J.   +8 more
europepmc   +1 more source

Designing Cyclic Nitrogen‐Bridged Sulfonamides with Anti‐Cancer Activity

ChemMedChem, EarlyView.
Nitrogen bridgehead compounds, especially cyclic sulfonamides, are an abundant motif in bioactive compounds. simple methods for the synthesis of nitrogen bridgehead sulfonamides is developed and their activity against cancer cell lines is explored. The N‐bridgehead heterocyclic structure is an abundant motif in a multitude of natural products.
Benedikt W. Grau, Arpit Dheeraj, Irimpan I. Mathews, Dhanir Tailor, Sanjay V. Malhotra   +4 more
wiley   +1 more source

Synthesis and Cardiovascular Activity of 3-(3, 4-Dimethoxy or Dihydroxyphenyl)piperidine Derivatives

, 1967
MUNEYOSHI IKEZAKI, Masanori Sato, Hiroshi Kugita   +2 more
openalex   +2 more sources