Inhibition of Sterol Biosynthesis by 2-Isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine Carboxylate Methyl Chloride in Tobacco and Rat Liver Preparations [PDF]
Trevor J. Douglas, L. G. Paleg
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Integrating Enzymes with Photoredox Catalysis for Conversion of Nitriles into Fluorinated Products
Herein, we describe a novel method for producing highly sought‐after fluorinated compounds through the integration of nitrilase enzymes and iridium photoredox catalysis in a convenient one‐pot reaction. Our chemo‐ biocatalytic methodology delivers a range of fluorinated and fluoroalkylated products from simple nitrile precursors, in good yields, at ...
Stuart Angiolini+6 more
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Adducts of Piperidine, Piperazine, Methylpiperazine, and Morpholine with Bis(β-Ketoenolates) of Nickel(II) [PDF]
G. MARCOTRIGIANO+2 more
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Functionalized Dialdehydes as Promising Scaffolds for Access to Heterocycles and beta-Amino Acids: Synthesis of Fluorinated Piperidine and Azepane Derivatives [PDF]
Functionalized dialdehydes are considered important substrates, which may be transformed into various substituted heterocycles, alicyclic and polysubstituted compounds.
Abrahami, Renata Anita+3 more
core
The Azidofunctionalization of Alkenes
The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
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Synthesis of enantiopure trisubstituted piperidines from a chiral epoxyaziridine and α-amino esters [PDF]
Concellón Gracia, José Manuel+2 more
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GA: Sulfonimidoyl fluorides react with a diverse set of amines in a HOBt‐catalyzed sulfur(VI) fluorine exchange reaction to access sulfonimidamides, including directly NH‐sulfonimidamides, and in an automated workflow. In addition, SNAr reactivity of 4‐fluoroaryl sulfonimidoyl fluorides is discovered and exploited to prepare complex sulfonimidoyl ...
Dominique Deans+6 more
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The stereoselective addition of chiral and achiral titanium enolates derived from the corresponding N-acyl oxazolidin-2-ones to 5- and 6- membered N-acyliminium ions afforded 2-substituted pyrrolidines in moderate to good diastereoisomeric ratio (5:1 to ...
Pilli Ronaldo A.+2 more
doaj
Studies on Piperidine Derivatives. I. A New Synthesis of dl-Pelletierine Acetal
Midori Ohta, 磯和 義員
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Asymmetric α-amidoalkylation. Synthesis of α-substituted piperidines of high enantiomeric purity [PDF]
Kärtner, Annerose, Wanner, Klaus Th.
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