Results 11 to 20 of about 47,089 (385)

Search for Antiviral Preparations in Series of New Derivatives of N-Substituted Piperidines [PDF]

Molecules
Cyanohydrin synthesis, as the simplest preparative method for introducing a carboxyl group into a piperidine molecule, has been used to obtain potentially biologically active piperidinecarboxylic acids, which have alkyl and arylalkyl radicals at the ...
Gulmira S. Akhmetova, Ulzhalgas B. Issayeva, Kaldybay D. Praliyev, Ilya S. Korotetskiy, Tulegen M. Seilkhanov, Samir A. Ross, Manas T. Omyrzakov, Ubaidilla M. Datkhayev, Khaidar S. Tassibekov, Lyudmila N. Ivanova, Natalya V. Zubenko   +10 more
doaj   +2 more sources

Enantioselective synthesis of chiral 2,3-cis-disubstituted piperidines and C1-substituted tetrahydroisoquinolines by asymmetric Cu-catalyzed cyclizative aminoboration [PDF]

Nature Communications
Chiral N-heterocycles such as piperidines and tetrahydroisoquinolines are privileged structural motifs in drug discovery and pharmaceutical industry.
Dazhuang Zhang, He Yang, Qinghai Zhou, Wenjun Tang   +3 more
doaj   +2 more sources

Über γ‐substituierte Piperidine [PDF]

Berichte der deutschen chemischen Gesellschaft, 1915
n ...
Ernst Koenigs, Ludwig Neumann
openalex   +4 more sources

"PIPERIDINE AS A URIC ACID SOLVENT.' [PDF]

The Lancet, 1898
n ...
ArthurP. Luff
openalex   +4 more sources

METABOLITES OF PIPERIDINE IN RAT URINE

Japanese Journal of Pharmacology, 1978
Piperidine is one of pharmacologically active biogenic amines. While two pathways for piperidine production have been reported, little is known about metabolism of the compound. In the present study, piperidine and its hydroxylated, conjugated and unknown metabolites were detected in rat urine by radiochromatographic analysis. Using GC-MS technique, it
Yoshiro Okano, Takeshi Miyata, Shiang-Huey HUNG, Toshiro Motoya, Mikiko Kataoka, Kazuo Takahama, Yoshitoshi Kasé   +6 more
openalex   +5 more sources

Designing chemical systems for precision deuteration of medicinal building blocks [PDF]

Nature Communications
Methods are lacking that can prepare deuterium-enriched building blocks, in the full range of deuterium substitution patterns at the isotopic purity levels demanded by pharmaceutical use.
Jonathan D. Dabbs, Caleb C. Taylor, Martin S. Holdren, Sarah E. Brewster, Brian T. Quillin, Alvin Q. Meng, Diane A. Dickie, Brooks H. Pate, W. Dean Harman   +8 more
doaj   +2 more sources

Experimental study of the pharmacological activity of new azaheterocycles derivatives: A literature review [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2022
Diseases associated with the pathology of the cardiovascular system are one of the key causes of death all over the world. In particular, arrhythmia may entail the most severe complications, including unexpected death.
Malika Khaiitova, Aida Seitaliyeva, Elmira Satbayeva, Daniya Serdalieva, Talgat Nurgozhin   +4 more
doaj   +1 more source

Synthesis of piperidines and pyridine from furfural over a surface single-atom alloy Ru1CoNP catalyst

Nature Communications, 2023
The sustainable production of value-added N-heterocycles from available biomass allows to reduce the reliance on fossil resources and creates possibilities for economically and ecologically improved synthesis of fine and bulk chemicals.
Haifeng Qi, Yurou Li, Zhitong Zhou, Yueqiang Cao, Fei Liu, Weixiang Guan, Leilei Zhang, Xiaoyan Liu, Lin Li, Yang Su, K. Junge, Xuezhi Duan, Matthias Beller, Aiqin Wang, Tao Zhang   +14 more
semanticscholar   +1 more source

Catalytic Enantioselective Synthesis of 3-Piperidines from Arylboronic Acids and Pyridine

Journal of the American Chemical Society, 2023
Piperidines are frequently found in natural products and are of importance to the pharmaceutical industry. A generally useful asymmetric route to enantiomerically enriched 3-substituted piperidines remains elusive.
Sourabh Mishra, Sedef Karabiyikoglu, S. Fletcher   +2 more
semanticscholar   +1 more source

Synthesis and Characterization of Novel Methyl (3)5-(N-Boc-piperidinyl)-1H-pyrazole-4-carboxylates

Molecules, 2021
Series of methyl 3- and 5-(N-Boc-piperidinyl)-1H-pyrazole-4-carboxylates were developed and regioselectively synthesized as novel heterocyclic amino acids in their N-Boc protected ester form for achiral and chiral building blocks.
Gita Matulevičiūtė, Eglė Arbačiauskienė, Neringa Kleizienė, Vilija Kederienė, Greta Ragaitė, Miglė Dagilienė, Aurimas Bieliauskas, Vaida Milišiūnaitė, Frank A. Sløk, Algirdas Šačkus   +9 more
doaj   +1 more source