Results 81 to 90 of about 3,430 (196)

New Onset of Primary Membranous Nephropathy After COVID‐19 mRNA Vaccination in Affected Sjögren's Syndrome

Nephrology, Volume 30, Issue 5, May 2025.
ABSTRACT The global administration of mRNA vaccines in response to the coronavirus disease 2019 (COVID‐19) pandemic has been crucial in mitigating the spread of the virus. While these vaccines are generally safe and effective, there have been occasional reports of rare adverse effects, including new‐onset nephropathies. Primary Sjögren's syndrome (pSS),
Chia‐Wei Tseng, Jing‐Huan Liao, Tai‐Kuang Chao, Shun‐Neng Hsu   +3 more
wiley   +1 more source

Anti-PLA2R antibody in primary and secondary forms of membranous glomerulopathy

, 2023
INTRODUÇÃO: A glomerulopatia membranosa (GNM) é considerada a principal causa de síndrome nefrótica em adultos. A maioria dos casos é considerada primária, mas cerca de 20-30% das GNM são secundárias a uma condição clínica subjacente, como neoplasias ...
Gazeta, Cristina do Amaral [UNIFESP]
core  

Expression of phospholipase A2 receptor and IgG4 in patients with membranous nephropathy

Vascular Health and Risk Management, 2018
Lei Liu,1 Baochao Chang,1 Xueping Wu,1 Yaling Guo,1 Yan Pan,1 Lijuan Yang2 1Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Anhui, People’s Republic of China; 2Department of Physiology, Bengbu Medical College ...
Liu L, Chang B, Wu X, Guo Y, Pan Y, Yang L   +5 more
doaj  

Nephrotic Syndrome: Beyond Common Causes

Nephrology, Volume 30, Issue 4, April 2025.
ABSTRACT We report the case of a 38‐year‐old Caucasian man with well‐controlled HIV on antiretroviral therapy who developed nephrotic syndrome. The patient presented with a maculopapular rash, lymphadenopathy, oral lesions, nasal congestion and bilateral pitting oedema. Laboratory tests revealed hypoalbuminemia, nephrotic range proteinuria and abnormal
Humam Hazim, Ryan Horn, Ashwati Krishnan Varikara, Joanna Mesure, Bobby Chacko   +4 more
wiley   +1 more source

Hepatitis B Antigenaemia, Nephrotic Syndrome and Pulmonary Embolism A Series of Unfortunate Events: A Case Report

Respirology Case Reports, Volume 13, Issue 3, March 2025.
We present an interesting case where a patient with chronic hepatitis B infection develops antigenaemia and nephrotic syndrome, and subsequent pulmonary embolism, highlighting the intricate interplay between viral hepatitis, renal disease and hypercoagulability. ABSTRACT Hepatitis B is a major health concern.
Muhammad Hassaan Malik, Muhammad Shaheer Bin Faheem, Khawaja Shaheryar, Javed Iqbal, Syed Aun Bin Nasar   +4 more
wiley   +1 more source

Can use of the serum anti-PLA2R antibody negate the need for a renal biopsy in primary membranous nephropathy?

, 2023
Background Since the emergence of the anti-PLA2R antibody (PLA2R-Ab) test, nephrology practice has not changed dramatically, with most nephrologists still relying on a kidney biopsy to diagnose membranous nephropathy.
Vilma Rautemaa, Smith, A, Smith, Alison, Durga Kanigicherla, Brenchley, Paul; id_orcid, Hamilton, P, Paul Brenchley, Brenchley, P, Rautemaa, Vilma, Patrick Hamilton, Rautemaa, V, Ragy, O, Alison Smith, Hamilton, Patrick, Kanigicherla, Durga, Ragy, Omar, Kanigicherla, D, Omar Ragy   +17 more
core   +1 more source

Identification of a Major Epitope Recognized by PLA2R Autoantibodies in Primary Membranous Nephropathy.

, 2014
Phospholipase A2 receptor 1 (PLA2R) is a target autoantigen in 70% of patients with idiopathic membranous nephropathy. We describe the location of a major epitope in the N-terminal cysteine-rich ricin domain of PLA2R that is recognized by 90% of human ...
Gummadova, Jennet, McKenzie, Edward A, Brenchley, Paul E; id_orcid, Jowitt, Thomas A; id_orcid, Fresquet, Maryline; id_orcid, Lennon, Rachel; id_orcid, O'Cualain, Ronan, Collins, Richard   +7 more
core   +1 more source

Primary glomerular diseases and long‐term adverse health outcomes: A nationwide cohort study

Journal of Internal Medicine, Volume 297, Issue 1, Page 22-35, January 2025.
Abstract Background Although glomerular diseases are the third most frequent cause of end‐stage kidney disease worldwide, little is known about their long‐term outcomes. Methods In patients with chronic kidney disease (CKD) stage 3–5 enrolled in the Swedish Renal Registry, we compared risks of hospitalization, kidney replacement therapy (KRT), major ...
Anne‐Laure Faucon, Stefania Lando, Charikleia Chrysostomou, Julia Wijkström, Sigrid Lundberg, Rino Bellocco, Mårten Segelmark, Marie Evans, Juan‐Jesús Carrero   +8 more
wiley   +1 more source

Schematic of epitope spreading of PLA2R.

BackgroundM-type phospholipase A2 receptor (PLA2R) is the major autoantigen in adult idiopathic membranous nephropathy (IMN). Although reactive epitopes in the PLA2R domains have been identified, the clinical value of these domains recognized by anti ...
Yuan Qin (260617), Zhigang Hu (477325), Xiumei Zhou (126818), Qingqing Wu (1969732), Xue Yang (144876), Bo Lin (116835), Zijian Huang (10776416), Xiaobin Liu (344083), Liang Wang (23021), Ting Li (117885), Jing Xue (170229), Leting Zhou (12062753), Biao Huang (215504), Huiming Sheng (485213)   +13 more
core   +1 more source

Kidney biopsy is a sensitive tool for retrospective diagnosis of PLA2R-related membranous nephropathy.

, 2013
International audienceBACKGROUND: Antibodies against M-type phospholipase A2 receptor (PLA2R) are serological markers of disease activity in patients with idiopathic membranous nephropathy (iMN).
Honsova, Eva, Tesar, Vladimir, Ronco, Pierre, Debiec, Hanna, Svobodova, Barbora   +4 more
core   +1 more source