The application of podocyte antigen PLA2R and anti-PLA2R antibody in the diagnosis and treatment of membranous nephropathy [PDF]
Renal Failure, 2023 Background The application of podocyte antigen M-type phospholipase A2 receptor (PLA2R, GAg) and serum anti-PLA2R antibody (SAb) in predicting the prognosis of membrane nephropathy (MN) was controversial.Method 328 biopsy-proven MN patients were divided ...
Yang Chen +5 more
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The cutoff value and prognosis of anti-PLA2R antibody for idiopathic membranous nephropathy: a single-center retrospective study in China [PDF]
Renal Failure, 2023 Serum anti-phospholipase A2 receptor (anti-PLA2R) antibody is used for the noninvasive diagnosis of idiopathic membranous nephropathy (IMN). However, the cutoff value of anti-PLA2R antibodies in IMN patients is debatable.
Hongxia Guo +5 more
doaj +5 more sources
Clinical value of a serum anti-PLA2R antibody in the diagnosis and monitoring of primary membranous nephropathy in adults [PDF]
International Journal of Nephrology and Renovascular Disease, 2018 Xueping Wu,1 Lei Liu,1 Yaling Guo,1 Lijuan Yang2 1Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People’s Republic of China; 2Department of Physiology, Bengbu Medical College, Bengbu, Anhui, People&
Wu X, Liu L, Guo Y, Yang L
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Anti-PLA2R antibody measured by ELISA predicts the risk of vein thrombosis in patients with primary membranous nephropathy [PDF]
Renal Failure, 2022 Background Primary membranous nephropathy (PMN) is associated with the highest risk for developing venous thrombosis compared with other nephrotic diseases.
Huizi Zhu +6 more
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Monitoring anti-PLA2R antibody titres to predict the likelihood of spontaneous remission of membranous nephropathy. [PDF]
Clin Kidney J, 2021 ABSTRACT Background In anti-phospholipase A2 receptor (PLA2R) membranous nephropathy (MN) there is controversy whether spontaneous remission (SR) can be predicted using a single titre or by assessing the dynamic changes in anti-PLA2R antibody (ab) titres.
Jatem-Escalante E +8 more
europepmc +9 more sources
Can use of the serum anti-PLA2R antibody negate the need for a renal biopsy in primary membranous nephropathy? [PDF]
PLoS ONE, 2023 Background Since the emergence of the anti-PLA2R antibody (PLA2R-Ab) test, nephrology practice has not changed dramatically, with most nephrologists still relying on a kidney biopsy to diagnose membranous nephropathy.
Omar Ragy +5 more
doaj +4 more sources
Serum and urine anti-PLA2R antibody correlation with albuminuria in idiopathic membranous nephropathy [PDF]
Frontiers in ImmunologyObjectiveThis study aimed to investigate the correlation between anti-phospholipase A2 receptor (PLA2R) levels in serum and urine with clinical parameters, particularly albuminuria, in patients with idiopathic membranous nephropathy (IMN).MethodsWe ...
Xiaogang Liu +4 more
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The role of serum BAFF, CFB, MCP-1 and anti-PLA2R antibodies in the efficacy evaluation of patients with membranous nephropathy [PDF]
Journal of Medical BiochemistryBackground: Monocyte chemoattractant protein-1 (MCP-1), serum B-cell activating factor (BAFF), complement B factor (CFB), and anti-M-type phospholipase A2 receptor (PLA2R) antibodies are investigated in relation to membranous nephropathy (MN), and their ...
Zheng Kaiyuan +3 more
doaj +2 more sources
Serum anti-PLA2R negativity does not exclude glomerular PLA2R expression in primary membranous nephropathy [PDF]
Biomolecules & BiomedicinePrimary membranous nephropathy (pMN) is a principal cause of nephrotic syndrome in adults. The identification of the M-type phospholipase A2 receptor (PLA2R) antigen has significantly advanced non-invasive management; however, the precise clinical ...
Şenay Yıldırım +5 more
doaj +2 more sources
Renal Failure, 2022 Objective To verify glomerular PLA2R antigen and serum PLA2R antibody expression in membranous nephropathy as well as to explore glomerular PLA2R efficacy in evaluating the prognosis of idiopathic membranous nephropathy (IMN) in the background of ...
Yuemeng Sun +6 more
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