The application of podocyte antigen PLA2R and anti-PLA2R antibody in the diagnosis and treatment of membranous nephropathy [PDF]
Renal Failure, 2023 Background The application of podocyte antigen M-type phospholipase A2 receptor (PLA2R, GAg) and serum anti-PLA2R antibody (SAb) in predicting the prognosis of membrane nephropathy (MN) was controversial.Method 328 biopsy-proven MN patients were divided ...
Yang Chen +5 more
doaj +6 more sources
The cutoff value and prognosis of anti-PLA2R antibody for idiopathic membranous nephropathy: a single-center retrospective study in China [PDF]
Renal Failure, 2023 Serum anti-phospholipase A2 receptor (anti-PLA2R) antibody is used for the noninvasive diagnosis of idiopathic membranous nephropathy (IMN). However, the cutoff value of anti-PLA2R antibodies in IMN patients is debatable.
Hongxia Guo +5 more
doaj +6 more sources
Anti-PLA2R antibody measured by ELISA predicts the risk of vein thrombosis in patients with primary membranous nephropathy [PDF]
Renal Failure, 2022 Background Primary membranous nephropathy (PMN) is associated with the highest risk for developing venous thrombosis compared with other nephrotic diseases.
Huizi Zhu +6 more
doaj +6 more sources
Can use of the serum anti-PLA2R antibody negate the need for a renal biopsy in primary membranous nephropathy? [PDF]
PLoS ONE, 2023 Background Since the emergence of the anti-PLA2R antibody (PLA2R-Ab) test, nephrology practice has not changed dramatically, with most nephrologists still relying on a kidney biopsy to diagnose membranous nephropathy.
Omar Ragy +5 more
doaj +5 more sources
Monitoring anti-PLA2R antibody titres to predict the likelihood of spontaneous remission of membranous nephropathy. [PDF]
Clin Kidney J, 2021 ABSTRACT Background In anti-phospholipase A2 receptor (PLA2R) membranous nephropathy (MN) there is controversy whether spontaneous remission (SR) can be predicted using a single titre or by assessing the dynamic changes in anti-PLA2R antibody (ab) titres.
Jatem-Escalante E +8 more
europepmc +7 more sources
Serum and urine anti-PLA2R antibody correlation with albuminuria in idiopathic membranous nephropathy [PDF]
Frontiers in ImmunologyObjectiveThis study aimed to investigate the correlation between anti-phospholipase A2 receptor (PLA2R) levels in serum and urine with clinical parameters, particularly albuminuria, in patients with idiopathic membranous nephropathy (IMN).MethodsWe ...
Xiaogang Liu +4 more
doaj +4 more sources
Clinical value of a serum anti-PLA2R antibody in the diagnosis and monitoring of primary membranous nephropathy in adults [PDF]
International Journal of Nephrology and Renovascular Disease, 2018 Xueping Wu,1 Lei Liu,1 Yaling Guo,1 Lijuan Yang2 1Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, People’s Republic of China; 2Department of Physiology, Bengbu Medical College, Bengbu, Anhui, People&
Wu X, Liu L, Guo Y, Yang L
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Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy. [PDF]
Clin J Am Soc Nephrol, 2023 Background The 2021 Kidney Disease Improving Global Outcomes (KDIGO) guidelines recommend following anti-phospholipase A2 receptor (PLA2R) antibody levels as a marker of treatment response in membranous nephropathy; however, the optimal timing to evaluate antibody levels and how to combine them with other clinical variables are
Barbour SJ +14 more
europepmc +3 more sources
Urine anti-PLA2R antibody is a novel biomarker of idiopathic membranous nephropathy. [PDF]
Oncotarget, 2018 Since urine samples more directly reflect kidney alterations and damage than blood samples, we investigated whether urine anti-PLA2R antibody (uPLA2R-Ab) could be utilized similarly to serum anti-PLA2R antibody (sPLA2R-Ab) as a noninvasive biomarker of idiopathic membranous nephropathy (IMN).
Wang Y +12 more
europepmc +4 more sources
Clinica Chimica Acta, 2023 This study aimed to compare the performance of enzyme-linked immunosorbent assay (ELISA) and magnetic particle chemiluminescence immunoassay (MP-CLIA) for detecting anti-phospholipase A2 receptor (PLA2R) antibody and their clinical significance in idiopathic membranous nephropathy (IMN) patients.Serum samples from 448 patients with different types of ...
Huangmin Li +2 more
exaly +3 more sources