Results 21 to 30 of about 145,320 (184)

Serum anti-PLA2R antibody and glomerular PLA2R deposition in Chinese patients with membranous nephropathy: A cross-sectional study. [PDF]

open access: yesMedicine (Baltimore), 2017
M-type phospholipase A2 receptor (PLA2R) is the major target antigen in primary membranous nephropathy (PMN). Previous studies have evaluated the diagnostic value of serum anti-PLA2R antibody. However, the correlation of serum anti-PLA2R antibody and glomerular PLA2R deposition, and their association with clinical characteristics need to be further ...
Pang L   +7 more
europepmc   +3 more sources

Primary antiphospholipid syndrome associated with anti-phospholipase A2 receptor antibody-positive membranous nephropathy

open access: yesBMC Nephrology, 2020
Background The kidney is a major target in primary antiphospholipid syndrome. Several types of nephropathy have been reported, the most frequent being acute or chronic specific vascular nephropathies and membranous nephropathy.
Maxime Teisseyre   +6 more
doaj   +2 more sources

Anti-phospholipase A2 receptor antibody in idiopathic membranous nephropathy: A report from Iranian population [PDF]

open access: yesJournal of Nephropathology, 2013
Background: Idiopathic Membranous Nephropathy (iMN) is the most common cause of nephrotic syndrome in adults. Approximately one third of patients with iMN progress to end-stage renal disease.
MohammadReza Ardalan   +6 more
doaj   +2 more sources

An Evaluation of the Level of Anti-phospholipase A2 Receptor (PLA2R) Antibody in Different Pathological Types of Glomerulonephritis

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017
BACKGROUND AND OBJECTIVE: Nowadays, anti-phospholipase A2 receptor (PLA2R) antibody is recognized as a diagnostic biomarker for idiopathic membranous nephropathy (iMN) and is also used to assess disease progression.
F Sadadi   +4 more
doaj   +1 more source

Clinical outcomes of immunosuppressive therapy in patients with seronegative anti-PLA2R antibodies and PLA2R-related membranous nephropathy

open access: yesClinical and Experimental Nephrology
Abstract Background Idiopathic membranous nephropathy (IMN) is an autoimmune disease characterized by anti-PLA2R antibodies, which are linked to disease activity, prognosis, and relapse. While guidelines recommend immunosuppressive treatment for high antibody levels, the impact on PLA2R-negative patients remains unclear.
Haofei Hu, Qi-Jun Wan, Su Zhihang
exaly   +3 more sources

Clinical Features and Pathology of PLA2R and THSD7A-Associated Membranous Nephropathy: A Single-Center Study from China

open access: yesImmunoTargets and Therapy
Yan Pan, Wei Dong Chen, Lei Liu, Huijuan Yang, Baochao Chang, Caixia Cui Department of Nephrology, First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui Province, People’s Republic of ChinaCorrespondence: Wei Dong Chen, Email cwd2012@163 ...
Pan Y   +5 more
doaj   +2 more sources

Spontaneous Remission of Late Relapsing Membranous Nephropathy After Previous Immunosuppressant-Induced Remission: Case Report. [PDF]

open access: yesCase Rep Nephrol
This is the first detailed report of spontaneous remission of late relapsing membranous nephropathy (MN) after previous immunosuppressant‐induced remission. In March 2004, a 52‐year‐old Hispanic male presented with severe nephrotic syndrome with proteinuria of 13 g/24 h. The workup for infectious and autoimmune diseases was unrevealing.
Cao Y.
europepmc   +2 more sources

The value of PLA2R antigen and IgG subclass staining relative to anti-PLA2R seropositivity in the differential diagnosis of membranous nephropathy [PDF]

open access: yes, 2023
Background The diagnostic performance of PLA2R and IgG subclass staining of kidney biopsies relative to anti-PLA2R seropositivity in the differentiation of primary and secondary membranous nephropathy (pMN, sMN) was examined.
Béla Iványi   +7 more
core   +2 more sources

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