Results 21 to 30 of about 2,423,946 (178)

An Evaluation of the Level of Anti-phospholipase A2 Receptor (PLA2R) Antibody in Different Pathological Types of Glomerulonephritis

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017
BACKGROUND AND OBJECTIVE: Nowadays, anti-phospholipase A2 receptor (PLA2R) antibody is recognized as a diagnostic biomarker for idiopathic membranous nephropathy (iMN) and is also used to assess disease progression.
F Sadadi, E Taherkhani, Sh Ossareh, T Shoshtarizadeh, HR Khoddami Vishteh   +4 more
doaj   +1 more source

Circulating anti-phospholipase A2 receptor antibodies as a diagnostic and prognostic marker in Greek patients with idiopathic membranous nephropathy – a retrospective cohort study

Romanian Journal of Internal Medicine, 2019
Introduction. Circulating autoantibodies against phospholipase A2 receptor (anti-PLA2R) are recognized as key elements in the pathogenesis of idiopathic membranous nephropathy.
Provatopoulou Simella, Kalavrizioti Dimitra, Stangou Maria, Kouri Maria-Nikoleta, Kalliakmani Pantellitsa, Papasotiriou Marios, Papachristou Evangelos, Goumenos Dimitrios S., Papagianni Aikaterini   +8 more
doaj   +2 more sources

Urine anti-PLA2R antibody is a novel biomarker of idiopathic membranous nephropathy. [PDF]

Oncotarget, 2018
Since urine samples more directly reflect kidney alterations and damage than blood samples, we investigated whether urine anti-PLA2R antibody (uPLA2R-Ab) could be utilized similarly to serum anti-PLA2R antibody (sPLA2R-Ab) as a noninvasive biomarker of idiopathic membranous nephropathy (IMN).
Wang Y, He YX, Diao TT, Wei SY, Qi WR, Wang CC, Song SM, Bi M, Li CM, Zhang CX, Hou YP, Wei QJ, Li B.   +12 more
europepmc   +4 more sources

Clinical Features and Pathology of PLA2R and THSD7A-Associated Membranous Nephropathy: A Single-Center Study from China [PDF]

ImmunoTargets and Therapy
Yan Pan, Wei Dong Chen, Lei Liu, Huijuan Yang, Baochao Chang, Caixia Cui Department of Nephrology, First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui Province, People’s Republic of ChinaCorrespondence: Wei Dong Chen, Email cwd2012@163 ...
Pan Y, Chen WD, Liu L, Yang H, Chang B, Cui C   +5 more
doaj   +1 more source

Anti-PLA2R antibody reduction as a predictor of treatment response in primary membranous nephropathy: a retrospective study. [PDF]

J Bras Nefrol
Abstract Introduction: Primary membranous nephropathy (PMN) is a leading cause of nephrotic syndrome in adults. Although proteinuria has been the conventional guiding parameter in disease monitoring, its limitations as a non-specific and delayed marker have led to the appeal of anti-phospholipase A2 receptor antibodies (PLA2R) as specific and ...
Bashir K, Asghar MR, Saleem N, Shahzil M, Riaz A, Hashmi MN, Sheraz A.   +6 more
europepmc   +4 more sources

Is Rituximab Suitable for Patients with Idiopathic Membranous Nephropathy Who are Seronegative for Anti-PLA2R Antibody? [PDF]

Drug Des Devel Ther
Rituximab (RTX) induces apoptosis in B cells expressing CD20, the efficacy in idiopathic membranous nephropathy (IMN) with seronegative anti-M-type phospholipase A2 receptor (PLA2R) antibody remains unclear.This multicenter retrospective study enrolled 111 adult patients with biopsy-proven, medium-to-high-risk IMN, whose serum anti-PLA2R antibodies ...
Yang Y, Xie X, Yuan F, Zeng F, Wang Y, Zhang R, Yan W, Luo K, Ren D, Xu G.   +9 more
europepmc   +4 more sources

Autoantibodies against phospholipase A2 receptor in Korean patients with membranous nephropathy. [PDF]

PLoS ONE, 2013
The data were presented in abstract form at the 45(th) meeting of the American Society of Nephrology, October 30-November 04 2012, San Diego, CA, USA. Circulating autoantibodies against M-type phospholipase A2 receptor (PLA2R) are important pathogenic ...
Yun Jung Oh, Seung Hee Yang, Dong Ki Kim, Shin-Wook Kang, Yon Su Kim   +4 more
doaj   +1 more source

Serum anti-phospholipase A2 receptor antibody in pathological diagnosis of type 2 diabetes mellitus patients with proteinuria

Scientific Reports, 2023
Patients with diabetes mellitus complicated with proteinuria can be diabetic nephropathy (DN), diabetic complicated with non-diabetic kidney disease (NDKD), or DN with NDKD.
Huanhuan Zhang, Yuanjie Zhu, Zhijuan Hu, Qiong Liu   +3 more
doaj   +1 more source

The characters of antibodies against PLA2R in healthy individuals and in the patient with PLA2R associated membranous nephropathy

European Journal of Medical Research, 2023
Background Most primary membranous nephropathy (MN) is mediated by anti-phospholipase A2 receptor (PLA2R) antibodies. Recently, these antibodies have been revealed months to years before the disease's onset.
Yan-jiao Cheng, Miao Wang, Jia Wang, Zhao Cui, Ming-hui Zhao   +4 more
doaj   +1 more source

Posttransplant membranous nephropathy - A case report

Indian Journal of Transplantation, 2022
Primary membranous nephropathy (PMN) is a common cause of adult-onset nephrotic syndrome. Anti-M-type phospholipase A2 receptor (PLA2R) antibodies are pathogenic and correlate with clinical outcomes. The role of anti-PLA2R in recurrent PMN is unclear. In
Shabna Sullaiman, Prabhat Chauhan, Ashwani Kumar, Ritambhra Nada, Ranjana Minz, Vinod Kumar, Ashish Sharma, Sarbpreet Singh, Vivek Kumar, Manish Rathi, Harbir Singh Kohli, Raja Ramachandran   +11 more
doaj   +1 more source